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ORIGINAL RESEARCH

Alpha-1 Antitrypsin Augmentation Therapy and Biomarkers of Elastin Degradation

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Pages 473-481 | Published online: 05 Apr 2013

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Ji-Yong Moon, Fernando Sergio Leitao Filho, Kimeya Shahangian, Hiroto Takiguchi & Don D. Sin. (2018) Blood and sputum protein biomarkers for chronic obstructive pulmonary disease (COPD). Expert Review of Proteomics 15:11, pages 923-935.
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Alessandro N Franciosi, Cormac McCarthy & Noel Gerry McElvaney. (2015) The efficacy and safety of inhaled human α-1 antitrypsin in people with α-1 antitrypsin deficiency-related emphysema. Expert Review of Respiratory Medicine 9:2, pages 143-151.
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James K. Stoller. (2013) Elastin Degradation Products as Biomarkers in Alpha-1 Antitrypsin Deficiency: Lastin’ Impact?. COPD: Journal of Chronic Obstructive Pulmonary Disease 10:4, pages 403-404.
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Articles from other publishers (26)

Igor Barjaktarevic & Michael Campos. (2021) Management of lung disease in alpha-1 antitrypsin deficiency: what we do and what we do not know. Therapeutic Advances in Chronic Disease 12_suppl, pages 204062232110101.
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Noriko M. Matsumoto, Masayo Aoki, Yuri Okubo, Kosuke Kuwahara, Shigeyoshi Eura, Teruyuki Dohi, Satoshi Akaishi & Rei Ogawa. (2020) Gene Expression Profile of Isolated Dermal Vascular Endothelial Cells in Keloids. Frontiers in Cell and Developmental Biology 8.
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Michael E O'Brien, Laura Fee, Niall Browne, Tomás P Carroll, Paula Meleady, Michael Henry, Karen McQuillan, Mark P Murphy, Mark Logan, Cormac McCarthy, Oliver J McElvaney, Emer P Reeves & Noel G McElvaney. (2020) Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency. Thorax 75:4, pages 321-330.
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Alessandro N Franciosi, Tomás P Carroll & Noel G McElvaney. (2019) Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians. The Lancet Respiratory Medicine 7:12, pages 1059-1067.
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Michael A. Campos, Patrick Geraghty, Gregory Holt, Eliana Mendes, Paul R. Newby, Shuren Ma, Landy V. Luna-Diaz, Gerard M. Turino & Robert A. Stockley. (2019) The Biological Effects of Double-Dose Alpha-1 Antitrypsin Augmentation Therapy. A Pilot Clinical Trial. American Journal of Respiratory and Critical Care Medicine 200:3, pages 318-326.
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Shuren Ma, Patrick Geraghty, Abdoulaye Dabo, Cormac McCarthy, N. Gerry McElvaney & Gerard M. Turino. (2019) Cystic fibrosis disease severity correlates with plasma levels of desmosine and isodesmosine, biomarkers of elastin degradation. ERJ Open Research 5:2, pages 00250-2018.
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A.P. Lopes, M.A. Mineiro, F. Costa, J. Gomes, C. Santos, C. Antunes, D. Maia, R. Melo, M. Canotilho, E. Magalhães, I. Vicente, C. Valente, B.G. Gonçalves, B. Conde, C. Guimarães, C. Sousa, J. Amado, M.E. Brandão, M. Sucena, M.J. Oliveira, S. Seixas, V. Teixeira & L. Telo. (2018) Portuguese consensus document for the management of alpha-1-antitrypsin deficiency. Pulmonology 24, pages 1-21.
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Miriam Barrecheguren & Marc Miravitlles. (2018) Tratamiento aumentativo para el enfisema por déficit de alfa-1 antitripsina: Pro. Archivos de Bronconeumología 54:7, pages 363-364.
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Miriam Barrecheguren & Marc Miravitlles. (2018) Augmentation Therapy for Emphysema due to Alpha-1 Antitrypsin Deficiency: Pro. Archivos de Bronconeumología (English Edition) 54:7, pages 363-364.
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Gerard M. Turino. (2018) Chronic Obstructive Pulmonary Disease. A Biomarker and a Potential Therapy. Annals of the American Thoracic Society 15:Supplement_1, pages S15-S17.
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Dieter Köhler. (2017) Alpha-1-Antitrypsin-Mangel: Ist die Substitution ein Mythos?. Deutsches Ärzteblatt Online.
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Ruth Minkin, Gagangeet Sandhu, Horiana Grosu, Lori Tartell, Shuren Ma, Yong Y. Lin, Edward Eden & Gerard M. Turino. (2017) Desmosine and Isodesmosine as a Novel Biomarker for Pulmonary Arterial Hypertension: A Pilot Study. American Journal of Therapeutics 24:4, pages e399-e404.
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Simona Viglio, Monica Di Venere, Maddalena Cagnone, Marco Fumagalli & Paolo Iadarola. 2017. Amino Acid - New Insights and Roles in Plant and Animal. Amino Acid - New Insights and Roles in Plant and Animal.
Michael Campos & Jorge Lascano. 2017. Alpha-1 Antitrypsin Deficiency. Alpha-1 Antitrypsin Deficiency 249 262 .
Umur Hatipoğlu & James K. Stoller. (2016) α1-Antitrypsin Deficiency. Clinics in Chest Medicine 37:3, pages 487-504.
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Gerard M. Turino, Shuren Ma, Jerome O. Cantor & Yong Y. Lin. (2016) Biomarkers in Alpha-1 Antitrypsin Deficiency Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society 13:Supplement_4, pages S336-S340.
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David A. Lomas. (2016) An ECLIPSE View of Alpha-1 Antitrypsin Deficiency. Annals of the American Thoracic Society 13:Supplement_4, pages S326-S331.
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Marni A. Nenke, Mark Holmes, Wayne Rankin, John G. Lewis & David J. Torpy. (2016) Corticosteroid-binding globulin cleavage is paradoxically reduced in alpha-1 antitrypsin deficiency: Implications for cortisol homeostasis. Clinica Chimica Acta 452, pages 27-31.
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Damian Bruce-Hickman, Catherine M. Greene & Bibek Gooptu. 2015. Controversies in COPD. Controversies in COPD 47 84 .
Francisco Casas, Ignacio Blanco, María Teresa Martínez, Ana Bustamante, Marc Miravitlles, Sergio Cadenas, José M. Hernández, Lourdes Lázaro, Esther Rodríguez, Francisco Rodríguez-Frías, María Torres & Beatriz Lara. (2015) Actualización sobre indicaciones de búsqueda activa de casos y tratamiento con alfa-1 antitripsina por vía intravenosa en pacientes con enfermedad pulmonar obstructiva crónica asociada a déficit de alfa-1 antitripsina. Archivos de Bronconeumología 51:4, pages 185-192.
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Francisco Casas, Ignacio Blanco, María Teresa Martínez, Ana Bustamante, Marc Miravitlles, Sergio Cadenas, José M. Hernández, Lourdes Lázaro, Esther Rodríguez, Francisco Rodríguez-Frías, María Torres & Beatriz Lara. (2015) Indications for Active Case Searches and Intravenous Alpha-1 Antitrypsin Treatment for Patients With Alpha-1 Antitrypsin Deficiency Chronic Pulmonary Obstructive Disease: An Update. Archivos de Bronconeumología (English Edition) 51:4, pages 185-192.
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Gabriele GrunigAram BaghdassarianSung-Hyun ParkSerhiy PylawkaBertram BleckJoan ReibmanErika Berman-RosenzweigNedim Durmus. (2016) Challenges and Current Efforts in the Development of Biomarkers for Chronic Inflammatory and Remodeling Conditions of the Lungs. Biomarker Insights 10s4, pages BMI.S29514.
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Patrick Geraghty, Edward Eden, Manju Pillai, Michael Campos, Noel G. McElvaney & Robert F. Foronjy. (2014) α 1 -Antitrypsin Activates Protein Phosphatase 2A to Counter Lung Inflammatory Responses . American Journal of Respiratory and Critical Care Medicine 190:11, pages 1229-1242.
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Michael A. Campos & Jorge Lascano. (2014) α1 Antitrypsin deficiency: current best practice in testing and augmentation therapy. Therapeutic Advances in Respiratory Disease 8:5, pages 150-161.
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Simona Viglio, Jan Stolk, Maurizio Luisetti, Fabio Ferrari, Paolo Piccinini & Paolo Iadarola. (2013) From micellar electrokinetic chromatography to liquid chromatography‐mass spectrometry: R evisiting the way of analyzing human fluids for the search of desmosines, putative biomarkers of chronic obstructive pulmonary disease . ELECTROPHORESIS 35:1, pages 109-118.
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Robert A. Stockley. (2013) Large Chronic Obstructive Pulmonary Disease Cohorts: Advantages and Caution in Biomarker Discovery/Validation. American Journal of Respiratory and Critical Care Medicine 188:12, pages 1387-1388.
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