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Journal of Immunotoxicology Volume 7, 2010 - Issue 3
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Research Article

Toxic effects of d-galactose on thymus and spleen that resemble aging

Mohammad Nizam UddinDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya, Japan
,
Naomi NishioDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya, Japan
,
Sachiko ItoDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya, Japan
,
Haruhiko SuzukiDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya, Japan
&
Ken-ichi IsobeDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya, JapanCorrespondence[email protected]
Pages 165-173 | Received 10 Sep 2009, Accepted 25 Nov 2009, Published online: 06 Jan 2010

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Jing Zhou, Xue Li, Yanping Wang, Yan Zhang, Xusen Jia, Jingmin Fan, Qiannian Zhang, Fangdi Hu & Wen Li. (2021) Interventional effect of Codonopsis pilosula oligosaccharides against d-galactose-induced aging in SD rats via suppression of oxidative stress, inflammation, and apoptosis. Journal of Carbohydrate Chemistry 40:1-3, pages 115-134.
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Articles from other publishers (22)

Xiaojuan Peng, Mingqian Hao, Yingchun Zhao, Yuan Cai, Xueyan Chen, Huiying Chen, Yue Zhang, Ling Dong, Xinglong Liu, Chuanbo Ding, Wencong Liu, Min Yang & Yunqing Luo. (2021) Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota. Phytomedicine 93, pages 153772.
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Federica Conte, Nicole van Buuringen, Nicol C. Voermans & Dirk J. Lefeber. (2021) Galactose in human metabolism, glycosylation and congenital metabolic diseases: Time for a closer look. Biochimica et Biophysica Acta (BBA) - General Subjects 1865:8, pages 129898.
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Cong Li & Song Shi. (2019) Neuroprotective Effect of Huperzine A on d -Galactose-Induced Hearing Dysfunction . Ear, Nose & Throat Journal 100:3_suppl, pages 269S-276S.
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Ting‐ting Wei, Yuan‐kang Feng, Jia‐hui Cao, Jie‐han Li, Shu‐liang Yuan, Yi Ding & Yu‐rong Chai. (2021) Dosage effects of resveratrol on thymus involution in D‐galactose‐treated mice. Journal of Food Biochemistry 45:5.
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Jie-han Li, Ting-ting Wei, Li Guo, Jia-hui Cao, Yuan-kang Feng, Shu-ning Guo, Guo-hong Liu, Yi Ding & Yu-rong Chai. (2020) Curcumin protects thymus against D-galactose-induced senescence in mice. Naunyn-Schmiedeberg's Archives of Pharmacology 394:2, pages 411-420.
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Koji Kawata, Takato Suzuki, Kazunori Ozawa & Miho Sekiguchi. (2021) Features of T-cell subset composition in a D-galactose-induced senescence mouse model. Experimental Animals 70:3, pages 284-292.
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Zhiqing Chen, Jie Xiao, Han Liu, Kangfei Yao, Xiaoning Hou, Yong Cao & Xiaojuan Liu. (2020) Astaxanthin attenuates oxidative stress and immune impairment in d -galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway . Food & Function 11:9, pages 8099-8111.
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Ting‐ting Wei, Meng‐jie Li, Li Guo, Yan‐dong Xie, Wen‐hui Chen, Yun Sun, Guo‐hong Liu, Yi Ding & Yu‐rong Chai. (2020) Resveratrol ameliorates thymus senescence changes in D‐galactose induced mice. Microbiology and Immunology 64:9, pages 620-629.
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Zhihong Wang, Yun Lin, Shang Jin, Tiannan Wei, Zhihai Zheng & Weimin Chen. (2020) Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. Aging 12:12, pages 11386-11397.
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Khairunnuur Fairuz Azman & Rahimah Zakaria. (2019) d-Galactose-induced accelerated aging model: an overview. Biogerontology 20:6, pages 763-782.
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Yerin Kim, Eunju Kim & Yuri Kim. (2019) l-histidine and l-carnosine accelerate wound healing via regulation of corticosterone and PI3K/Akt phosphorylation in d-galactose-induced aging models in vitro and in vivo. Journal of Functional Foods 58, pages 227-237.
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H. M. Du, Y. J. Wang, X. Liu, S. L. Wang, S. M. Wu, Z. Yuan & X. K. Zhu. (2019) Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging. Biochemistry (Moscow) 84:6, pages 617-626.
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Xie Zhang, Jia-Zhen Wu, Zhi-Xiu Lin, Qiu-Ju Yuan, Yu-Cui Li, Jia-Li Liang, Janis Ya-Xian Zhan, You-Liang Xie, Zi-Ren Su & Yu-Hong Liu. (2019) Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. Journal of Ethnopharmacology 234, pages 44-56.
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Wei Wu, Cui-Lan Hou, Xue-Pan Mu, Chen Sun, Yi-Chun Zhu, Ming-Jie Wang & Qian-Zhou Lv. (2017) H 2 S Donor NaHS Changes the Production of Endogenous H 2 S and NO in D-Galactose-Induced Accelerated Ageing . Oxidative Medicine and Cellular Longevity 2017, pages 1-14.
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ZHENGDE DU, SHUO LI, LIN LIU, QIONG YANG, HONGWEI ZHANG & CHUNSHENG GAO. (2015) NADPH oxidase 3-associated oxidative stress and caspase 3-dependent apoptosis in the cochleae of D-galactose-induced aged rats. Molecular Medicine Reports 12:6, pages 7883-7890.
Crossref
Faheem Ullah, Tahir Ali, Najeeb Ullah & Myeong Ok Kim. (2015) Caffeine prevents d-galactose-induced cognitive deficits, oxidative stress, neuroinflammation and neurodegeneration in the adult rat brain. Neurochemistry International 90, pages 114-124.
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Onno J. Arntz, Bartijn C.H. Pieters, Marina C. Oliveira, Mathijs G.A. Broeren, Miranda B. Bennink, Marieke de Vries, Peter L.E.M. van Lent, Marije I. Koenders, Wim B. van den Berg, Peter M. van der Kraan & Fons A.J. van de Loo. (2015) Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Molecular Nutrition & Food Research 59:9, pages 1701-1712.
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Ying Lu, Ming Ye, Sheng Song, Lan Li, Farnaz Shaikh & Junhong Li. (2014) Isolation, Purification, and Anti-Aging Activity of Melanin from Lachnum singerianum. Applied Biochemistry and Biotechnology 174:2, pages 762-771.
Crossref
Yan-Ying Liu, Bhushan Vijay Nagpure, Peter T.-H Wong & Jin-Song Bian. (2013) Hydrogen sulfide protects SH-SY5Y neuronal cells against d-galactose induced cell injury by suppression of advanced glycation end products formation and oxidative stress. Neurochemistry International 62:5, pages 603-609.
Crossref
C. Frieke Kuper, Christine Ruehl-Fehlert, Susan A. Elmore & George A. Parker. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 1795 1862 .
Yi Zhong, Yujuan Hu, Wei Peng, Yu Sun, Yang Yang, Xueyan Zhao, Xiang Huang, Honglian Zhang & Weijia Kong. (2012) Age-related decline of the cytochrome c oxidase subunit expression in the auditory cortex of the mimetic aging rat model associated with the common deletion. Hearing Research 294:1-2, pages 40-48.
Crossref
Mohammad Nizam Uddin, Naomi Nishio, Sachiko Ito, Haruhiko Suzuki & Ken-ichi Isobe. (2011) Autophagic activity in thymus and liver during aging. AGE 34:1, pages 75-85.
Crossref

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