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Research Article

Isoniazid-induced liver injury and immune response in mice

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Pages 383-392 | Received 12 Aug 2013, Accepted 27 Oct 2013, Published online: 04 Dec 2013

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Violina T. Angelova & Rumyana Simeonova. (2022) Effects of a new 1,2,3-thiadiazole containing hydrazone antimycobacterial agent on serum and liver biochemical parameters in female mice. Drug and Chemical Toxicology 45:1, pages 113-119.
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Tiffany Cho, Xijin Wang & Jack Uetrecht. (2019) Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury. Chemical Research in Toxicology 32:7, pages 1423-1431.
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Yingying Pan, Mingzhu Cao, Danming You, Genggeng Qin & Zhi Liu. (2019) Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives. BioMed Research International 2019, pages 1-12.
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Triyanta Yuli Pramana, Bambang Poerwanto, Suroto & Ambar Mudigdo. The effect of Garcinia mangostana L rind ethanol extract on transminase liver enzymes and Bilirubin on liver fibrosis rat model. The effect of Garcinia mangostana L rind ethanol extract on transminase liver enzymes and Bilirubin on liver fibrosis rat model.
Yuhong Li, Qi Ren, Lingyan Zhu, Yingshu Li, Jinfeng Li, Yiyang Zhang, Guoying Zheng, Tiesheng Han, Shufeng Sun & Fumin Feng. (2018) Involvement of methylation of MicroRNA-122, −125b and -106b in regulation of Cyclin G1, CAT-1 and STAT3 target genes in isoniazid-induced liver injury. BMC Pharmacology and Toxicology 19:1.
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Osama Abdel-Ghaf, Atef Abdel-Mone & Sara Abdel-Mohs. (2018) Protective Effect of Naringenin Against Isoniazid-induced Adverse Reactions in Rats. International Journal of Pharmacology 14:5, pages 667-680.
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Yu Chen, Peng Ye, Chongwu Ren, Pengfei Ren, Zheng Ma, Lin Zhang, Wenliang Zhou & Changjie Jiang. (2018) Pharmacoeconomics of three therapeutic schemes for anti-tuberculosis therapy induced liver injury in China. Open Medicine 13:1, pages 53-63.
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Chaitanya K. Jaladanki, Akbar Shaikh & Prasad V. Bharatam. (2017) Biotransformation of Isoniazid by Cytochromes P450: Analyzing the Molecular Mechanism using Density Functional Theory. Chemical Research in Toxicology 30:11, pages 2060-2073.
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Sisi Wang, Jian Zhang, Liyan Sui, Hao Xu, Qianling Piao, Ying Liu, Xinglong Qu, Ying Sun, Lei Song, Dan Li, Liping Peng, Shucheng Hua, Guangan Hu & Jianzhu Chen. (2017) Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis. Scientific Reports 7:1.
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Christopher Vinnard, Shruthi Ravimohan, Neo Tamuhla, Vijay Ivaturi, Jotam Pasipanodya, Shashikant Srivastava, Chawangwa Modongo, Nicola M. Zetola, Drew Weissman, Tawanda Gumbo & Gregory P. Bisson. (2016) Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation. British Journal of Clinical Pharmacology 83:4, pages 801-811.
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Hozeifa Mohamed Hassan, Hongli Guo, Bashir Alsiddig Yousef, Mounia Guerram, Aida Mejda Hamdi, Luyong Zhang & Zhenzhou Jiang. (2016) Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment. Antimicrobial Agents and Chemotherapy 60:9, pages 5285-5293.
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Imir Metushi, Jack Uetrecht & Elizabeth Phillips. (2016) Mechanism of isoniazid-induced hepatotoxicity: then and now. British Journal of Clinical Pharmacology 81:6, pages 1030-1036.
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Yilin Yang, Lulu Jiang, Shuo Wang, Tao Zeng & Keqin Xie. (2016) Diallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells. Toxicology Research 5:3, pages 954-962.
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Alastair Mak & Jack Uetrecht. (2015) The Combination of Anti-CTLA-4 and PD1–/– Mice Unmasks the Potential of Isoniazid and Nevirapine To Cause Liver Injury. Chemical Research in Toxicology 28:12, pages 2287-2291.
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Hozeifa M. Hassan, Hong-li Guo, Bashir A. Yousef, Zhang Luyong & Jiang Zhenzhou. (2015) Hepatotoxicity mechanisms of isoniazid: A mini-review. Journal of Applied Toxicology 35:12, pages 1427-1432.
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François Ballet. (2015) Preventing Drug-Induced Liver Injury: How Useful Are Animal Models?. Digestive Diseases 33:4, pages 477-485.
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Imir G. Metushi, Xu Zhu & Jack Uetrecht. (2014) D-penicillamine-induced granulomatous hepatitis in brown Norway rats. Molecular and Cellular Biochemistry 393:1-2, pages 229-235.
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Imir G. Metushi, William M. Lee & Jack Uetrecht. (2014) IgG 3 Is the Dominant Subtype of Anti-isoniazid Antibodies in Patients with Isoniazid-Induced Liver Failure . Chemical Research in Toxicology 27:5, pages 738-740.
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Imir G. Metushi, Xu Zhu, Xin Chen, Michael A. Gardam & Jack Uetrecht. (2014) Mild Isoniazid-Induced Liver Injury in Humans Is Associated with an Increase in Th17 Cells and T Cells Producing IL-10. Chemical Research in Toxicology 27:4, pages 683-689.
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Urs A Boelsterli & Kang Kwang Lee. (2014) Mechanisms of isoniazid-induced idiosyncratic liver injury: Emerging role of mitochondrial stress. Journal of Gastroenterology and Hepatology 29:4, pages 678-687.
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