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ArticlesCritical Care

When do the aminotransferases rise after acute acetaminophen overdose?

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Pages 787-792 | Received 16 Jun 2010, Accepted 10 Sep 2010, Published online: 25 Oct 2010

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Read on this site (15)

Angela L. Chiew & Geoffrey K. Isbister. (2023) Advances in the understanding of acetaminophen toxicity mechanisms: a clinical toxicology perspective. Expert Opinion on Drug Metabolism & Toxicology 0:0, pages 1-16.
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Annabelle S Chidiac, Nicholas A Buckley, Firouzeh Noghrehchi & Rose Cairns. (2023) Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease. Expert Opinion on Drug Metabolism & Toxicology 19:5, pages 297-317.
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J. C. Lewis, M. Lim, L. Lai, E. Mendoza, T. E. Albertson & J. A. Chenoweth. (2022) Evaluation of N-acetylcysteine dose for the treatment of massive acetaminophen ingestion. Clinical Toxicology 60:4, pages 507-513.
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Kamanashis Mahaldar, Amir Hossain, Fahrima Islam, Sharmin Islam, Md. Amirul Islam, Masum Shahriar & Md. Mustafizur Rahman. (2020) Antioxidant and hepatoprotective activity of Piper retrofractum against Paracetamol-induced hepatotoxicity in Sprague-Dawley rat. Natural Product Research 34:22, pages 3219-3225.
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Anselm Wong, Marco L. A. Sivilotti, Naren Gunja, Richard McNulty & Andis Graudins. (2018) Accuracy of the paracetamol-aminotransferase product to predict hepatotoxicity in paracetamol overdose treated with a 2-bag acetylcysteine regimen. Clinical Toxicology 56:3, pages 182-188.
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Anselm Wong & Andis Graudins. (2017) Risk prediction of hepatotoxicity in paracetamol poisoning. Clinical Toxicology 55:8, pages 879-892.
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Dushan Jayaweera, Shawkat Islam, Naren Gunja, Chris Cowie, James Broska, Latesh Poojara, Michael S. Roberts & Geoffrey K. Isbister. (2017) Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations. Clinical Toxicology 55:2, pages 147-150.
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R. Mason Curtis & Marco L. A. Sivilotti. (2016) Reply to Cantrell and Nordt. Clinical Toxicology 54:6, pages 537-537.
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Anselm Wong, Marco L. A. Sivilotti, Paul I. Dargan, David M. Wood & Shaun L. Greene. (2015) Response to Letter to the Editor: External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose. Clinical Toxicology 53:10, pages 1154-1154.
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R. Mason Curtis & Marco L. A. Sivilotti. (2015) A descriptive analysis of aspartate and alanine aminotransferase rise and fall following acetaminophen overdose. Clinical Toxicology 53:9, pages 849-855.
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Anselm Wong, Marco L. A. Sivilotti, Paul I. Dargan, David M. Wood & Shaun L. Greene. (2015) External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose. Clinical Toxicology 53:8, pages 807-814.
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Michael E. Mullins & Allison J. McGovern. (2015) Can AST/ALT ratio indicate recovery after acute paracetamol poisoning? The authors reply. Clinical Toxicology 53:6, pages 581-582.
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James W Dear & Daniel J Antoine. (2014) Stratification of paracetamol overdose patients using new toxicity biomarkers: current candidates and future challenges. Expert Review of Clinical Pharmacology 7:2, pages 181-189.
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W Stephen Waring. (2012) Criteria for acetylcysteine treatment and clinical outcomes after paracetamol poisoning. Expert Review of Clinical Pharmacology 5:3, pages 311-318.
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