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Clinical Toxicology Volume 50, 2012 - Issue 5
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Research Articles

Kinetics and metabolism of fomepizole in healthy humans

Kenneth E. McMartinDepartment of Pharmacology, Toxicology and Neuroscience, Lousiana State University Health Sciences Center – Shreveport, Shreveport, LA, USCorrespondence[email protected]
,
C. Simon SebastianDepartment of Psychiatry, Lousiana State University Health Sciences Center – Shreveport, Shreveport, LA, US
,
David DiesDepartment of Internal Medicine, Lousiana State University Health Sciences Center – Shreveport, Shreveport, LA, US
&
Dag JacobsenDepartment of Pharmacology, Toxicology and Neuroscience, Lousiana State University Health Sciences Center – Shreveport, Shreveport, LA, US;Department of Acute Medicine, Division of Medicine, Oslo University Hospital, Oslo, Norway
Pages 375-383 | Received 17 Feb 2012, Accepted 02 Apr 2012, Published online: 04 May 2012

Citations (18)

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Yvonne E. Lao, Trond Vartdal, Sten Froeyshov, Brian Latimer, Christiane Kvaerner, Marija Mataric, Peter Holm, Siri Foreid, Dag Jacobsen, Kenneth McMartin & Knut Erik Hovda. (2022) Fomepizole dosing during continuous renal replacement therapy – an observational study. Clinical Toxicology 60:4, pages 451-457.
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Garrett Rampon, Haley Wartman, Stephen Osmon & Anthony Scalzo. (2020) Use of fomepizole as an adjunct in the treatment of acetaminophen overdose: a case series. Toxicology Communications 4:1, pages 1-4.
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Jeffrey A. Kraut. (2015) Diagnosis of toxic alcohols: limitations of present methods. Clinical Toxicology 53:7, pages 589-595.
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Chen-Yen Lee, Eileen Kevyn Chang, Ja-Liang Lin, Cheng-Hao Weng, Shen-Yang Lee, Kuo-Chang Juan, Huang-Yu Yang, Chemin Lin, Shwu-Hua Lee, I-Kwan Wang & Tzung-Hai Yen. (2014) Risk factors for mortality in Asian Taiwanese patients with methanol poisoning. Therapeutics and Clinical Risk Management 10, pages 61-67.
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Rebeca Gracia, Brian Latimer & Kenneth E. McMartin. (2012) Kinetics of fomepizole in pregnant rats. Clinical Toxicology 50:8, pages 743-748.
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Articles from other publishers (13)

Ali Mohammad Pourbagher-Shahri, Jonathan Schimmel, Farshad M. Shirazi, Samaneh Nakhaee & Omid Mehrpour. (2022) Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning: A scoping review. Toxicology Letters 355, pages 47-61.
Crossref
Kenneth E. McMartin. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology 213 230 .
Kenneth McMartin & Jeffrey Brent. (2021) Analysis of Fomepizole Elimination in Methanol- and Ethylene Glycol-Poisoned Patients. Journal of Medical Toxicology 18:1, pages 19-29.
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Omid Mehrpour, Farhad Saeedi, Ali Hadianfar, Bruno Mégarbane & Christopher Hoyte. (2021) Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,000 patients. Human & Experimental Toxicology 40:12_suppl, pages S814-S825.
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Miroslav Pohanka. (2019) Antidotes Against Methanol Poisoning: A Review. Mini-Reviews in Medicinal Chemistry 19:14, pages 1126-1133.
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Ravi Kumar Jairam, Sadanand Rangnathrao Mallurwar, Suresh P. Sulochana, Devaraj V. Chandrasekhar, Umesh Todmal, Ravi Kanth Bhamidipati, Wolfgang Richter, Nuggehally R. Srinivas & Ramesh Mullangi. (2019) Prediction of Human Pharmacokinetics of Fomepizole from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles. AAPS PharmSciTech 20:6.
Crossref
Vaibhav A. Dixit, L. Arun Lal & Simran R. Agrawal. (2017) Recent advances in the prediction of non‐ CYP450 ‐mediated drug metabolism . WIREs Computational Molecular Science 7:6.
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Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 2829 2842 .
Kenneth McMartin, Dag Jacobsen & Knut Erik Hovda. (2016) Antidotes for poisoning by alcohols that form toxic metabolites. British Journal of Clinical Pharmacology 81:3, pages 505-515.
Crossref
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Deep Pandya, Marisa Mariani, Mark McHugh, Mirko Andreoli, Steven Sieber, Shiquan He, Candice Dowell-Martino, Paul Fiedler, Giovanni Scambia & Cristiano Ferlini. (2014) Herpes Virus MicroRNA Expression and Significance in Serous Ovarian Cancer. PLoS ONE 9:12, pages e114750.
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Anastasia V. Shindyapina, Igor V. Petrunia, Tatiana V. Komarova, Ekaterina V. Sheshukova, Vyacheslav S. Kosorukov, Gleb I. Kiryanov & Yuri L. Dorokhov. (2014) Dietary Methanol Regulates Human Gene Activity. PLoS ONE 9:7, pages e102837.
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