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Journal of Toxicology: Clinical Toxicology Volume 24, 1986 - Issue 5
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Research Article

Pharmacokinetics of Oral and Intravenous Bromide in Normal Volunteers

Nachum Vaiseman Division of Clinical Nutrition The Department of Pediatrics The Hospital for Sick children, and the Departments of Pediatrics and Pharmacology, The Research Institute, University of Toronto, Ontario, Canada
,
Gideon Koren Clinical Pharmacology The Department of Pediatrics, The Hospital for Sick children, and the Departments of Pediatrics and Pharmacology, The Research Institute, University of Toronto, Ontario, Canada
&
Paul Pencharz Division of Clinical Nutrition The Department of Pediatrics The Hospital for Sick children, and the Departments of Pediatrics and Pharmacology, The Research Institute, University of Toronto, Ontario, Canada
Pages 403-413 | Published online: 25 Sep 2008

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Mariam Sabir, Yen Yi Tan, Aleena Aris & Ali R. Mani. (2019) The role of endogenous bromotyrosine in health and disease. Free Radical Research 53:9-10, pages 1019-1034.
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B. Zane Horowitz. (1997) Bromism from Excessive Cola Consumption. Journal of Toxicology: Clinical Toxicology 35:3, pages 315-320.
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Cécile Derieux, Audrey Léauté, Agathe Brugoux, Déborah Jaccaz, Claire Terrier, Jean-Philippe Pin, Julie Kniazeff, Julie Le Merrer & Jerome A. J. Becker. (2022) Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism. Neuropsychopharmacology 47:9, pages 1680-1692.
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K. J. H. George, S. Borjian, M. C. Cross, J. W. Hicks, P. Schaffer & M. S. Kovacs. (2021) Expanding the PET radioisotope universe utilizing solid targets on small medical cyclotrons. RSC Advances 11:49, pages 31098-31123.
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T. Göen. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 14 .
Martin Holtkamp. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 689 700 .
Yang Zhou, Kwamena E. Baidoo & Martin W. Brechbiel. (2013) Mapping biological behaviors by application of longer-lived positron emitting radionuclides. Advanced Drug Delivery Reviews 65:8, pages 1098-1111.
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T. Göen. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 17 .
J. du Toit & N.H. Casey. (2012) Iodine as an alleviator of bromine toxicity in thyroid, liver and kidney of broiler chickens. Livestock Science 144:3, pages 269-274.
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M. Müller. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 97 112 .
M. Müller. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 14 .
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. (2009) <italic>N</italic>-Acetyl-<italic>S</italic>-(<italic>n</italic>-Propyl)-<sc>L</sc>-Cysteine in Urine from Workers Exposed to 1-Bromopropane in Foam Cushion Spray Adhesives. The Annals of Occupational Hygiene.
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SL Raidal & S Edwards. (2008) Pharmacokinetics of potassium bromide in adult horses. Australian Veterinary Journal 86:5, pages 187-193.
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Monica Aleman, Leah C. Gray, D. Colette Williams, Terrell A. Holliday, John E. Madigan, Richard A. LeCouteur & K. Gary Magdesian. (2008) Juvenile Idiopathic Epilepsy in Egyptian Arabian Foals: 22 Cases (1985–2005). Journal of Veterinary Internal Medicine 20:6, pages 1443-1449.
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Richard L. Braam, Stan H. M. van Uum, Frans G. M. Russel, Dorine W. Swinkels & Theo Thien. (2006) Bromide as a marker to measure adherence to drug therapy. European Journal of Clinical Pharmacology 62:4, pages 285-290.
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Mark Toraason, Dennis W. Lynch, D. Gayle DeBord, Narendra Singh, Edward Krieg, Mary Ann Butler, Christine A. Toennis & Jeffrey B. Nemhauser. (2006) DNA damage in leukocytes of workers occupationally exposed to 1-bromopropane. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 603:1, pages 1-14.
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SL RAIDAL & S. EDWARDS. (2005) Pharmacokinetics of potassium bromide in adult horses. Australian Veterinary Journal 83:7, pages 425-430.
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H. Meierkord. 2004. The Treatment of Epilepsy. The Treatment of Epilepsy 560 567 .
C. Langdon Fielding, K. Gary Magdesian, Denise A. Elliott, Arthur L. Craigmill, W. David Wilson & Gary P. Carlson. (2003) Pharmacokinetics and Clinical Utility of Sodium Bromide (NaBr) as an Estimator of Extracellular Fluid Volume in Horses. Journal of Veterinary Internal Medicine 17:2, pages 213-217.
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P. A. March, M. Podell & R. A. Sams. (2002) Pharmacokinetics and toxicity of bromide following high-dose oral potassium bromide administration in healthy Beagles. Journal of Veterinary Pharmacology and Therapeutics 25:6, pages 425-432.
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Chih‐Hao K. Kao, Mark B. Sassaman, Lawrence P. Szajek, Ying Ma, Atsuo Waki & William C. Eckelman. (2001) The sequential syntheses of [ 76 Br]FBAU 3′,5′‐dibenzoate and [ 76 Br]FBAU . Journal of Labelled Compounds and Radiopharmaceuticals 44:13, pages 889-898.
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Olafur Gudjonssona, Mats Bergström, Stefan Kristjansson, Feng Wu, Gunnar Nyberg, Karl-Johan Fasth & Bengt Långström. (2001) Analysis of 76Br-BrdU in DNA of brain tumors after a PET study does not support its use as a proliferation marker. Nuclear Medicine and Biology 28:1, pages 59-65.
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Olivier Gardelle, Ulrich Roelcke, Peter Vontobel, Nigel E.A. Crompton, Ilonka Guenther, Peter Bläuenstein, August P. Schubiger, Hans Blattmann, Jean E. Ryser, Klaus L. Leenders & Barbara Kaser-Hotz. (2001) [76Br]Bromodeoxyuridine PET in tumor-bearing animals. Nuclear Medicine and Biology 28:1, pages 51-57.
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Lindsay D. Plank & Graham L. Hill. 2001. Surgical Research. Surgical Research 797 812 .
Marieke Dijkgraaf-ten Bolscher, Rob Barto, Daphne A. Voorn, Dirk Compas, J.Coen Netelenbos & Wim J.F. van der Vijgh. (2000) Influence of ovariectomy on extracellular fluid volume in rats: Assessment of extracellular fluid volume by means of bromide. Journal of Laboratory and Clinical Medicine 135:4, pages 303-308.
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Koji Okuda, Akihiro Yasuhara, Atsushi Kamei, Atsushi Araki, Naoyuki Kitamura & Yohnosuke Kobayashi. (2000) Successful control with bromide of two patients with malignant migrating partial seizures in infancy. Brain and Development 22:1, pages 56-59.
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Li Lu, Mats Bergström, Karl-Johan Fasth, Feng Wu, Barbro Eriksson & Bengt Långström. (1999) Elimination of nonspecific radioactivity from [76Br]bromide in PET study with [76Br]bromodeoxyuridine. Nuclear Medicine and Biology 26:7, pages 795-802.
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. (2010) XIIth international symposium on radiopharmaceutical chemistry: Abstracts and programme. Journal of Labelled Compounds and Radiopharmaceuticals 40:5, pages 332-401.
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L.A Trepanier & J.G Babish. (1995) Pharmacokinetic properties of bromide in dogs after the intravenous and oral administration of single doses. Research in Veterinary Science 58:3, pages 248-251.
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Michael Podell & William R. Fenner. (2008) Bromide Therapy in Refractory Canine Idiopathic Epilepsy. Journal of Veterinary Internal Medicine 7:5, pages 318-327.
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