Advanced search
Publication Cover
Journal of Toxicology: Clinical Toxicology Volume 30, 1992 - Issue 2
Journal homepage
90
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Severe amitriptyline overdose: Relationship between toxicokinetics and toxicodynamics

Bengt-Åke Hultén Poisons Therapy Group, Department of Anaesthesia and Intensive Care, Gothenburg, Sweden
,
Andrew Heath Poisons Therapy Group, Department of Anaesthesia and Intensive Care, Gothenburg, Sweden
,
Kai Knudsen Poisons Therapy Group, Department of Anaesthesia and Intensive Care, Gothenburg, Sweden
,
Gösta Nyberg Lillhagens Hospital, Gothenburg, Sweden
,
Jan-Erik Starmark Department of Neurosurgery, Sahlgrens Hospital, Gothenburg, Sweden
&
Eric Mårtensson Lillhagens Hospital, Gothenburg, Sweden
Pages 171-179 | Published online: 25 Sep 2008

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Alan D. Woolf, Andrew R. Erdman, Lewis S. Nelson, E. Martin Caravati, Daniel J. Cobaugh, Lisa L. Booze, Paul M. Wax, Anthony S. Manoguerra, Elizabeth J. Scharman, Kent R. Olson, Peter A. Chyka, Gwenn Christianson & William G. Troutman. (2007) Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology 45:3, pages 203-233.
Read now
Hans Persson. (1992) European association of poison centres and clinical toxicologists. Journal of Toxicology: Clinical Toxicology 30:2, pages v-vii.
Read now

Articles from other publishers (17)

Motozumi Ando, Ryo Tamura, Shinji Nakasako, Satsuki Takimoto, Koichi Ariyoshi, Marie Yamaguchi, Kenji Sakizono, Masaaki Eto, Shoji Fukushima, Nobuyuki Sugioka & Tohru Hashida. (2020) Plasma concentration of amitriptyline and metabolites after resuscitation from cardiopulmonary arrest following an overdose: A case report. Clinical Case Reports 9:2, pages 805-811.
Crossref
Jonathan Royds, Melissa J. Conroy, Margaret R. Dunne, Connail McCrory & Joanne Lysaght. (2020) An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline. European Neuropsychopharmacology 31, pages 131-144.
Crossref
S Paksu, L Duran, M Altuntas, H Zengin, O Salis, SN Ozsevik, H Albayrak, N Murat, A Guzel & MS Paksu. (2014) Amitriptyline overdose in emergency department of university hospital. Human & Experimental Toxicology 33:9, pages 980-990.
Crossref
Pavan Vajjah, Geoffrey K. Isbister & Stephen B. Duffull. 2012. Computational Toxicology. Computational Toxicology 289 312 .
Gary A Gintant, David J Gallacher & Michael K Pugsley. (2011) The ‘overly-sensitive’ heart: sodium channel block and QRS interval prolongation. British Journal of Pharmacology 164:2, pages 254-259.
Crossref
Baruch S. Fertel, Lewis S. Nelson & David S. Goldfarb. (2010) Extracorporeal Removal Techniques for the Poisoned Patient: A Review for the Intensivist. Journal of Intensive Care Medicine 25:3, pages 139-148.
Crossref
Haşim Olgun, Zuhal Keskin Yldrm, Mehmet Karacan & Naci Ceviz. (2009) Clinical, Electrocardiographic, and Laboratory Findings in Children With Amitriptyline Intoxication. Pediatric Emergency Care 25:3, pages 170-173.
Crossref
KENAN BEK, OZAN ÖZKAYA, BİRGÜL MUTLU, AYHAN DAĞDEMİR, METİN SUNGUR, YONCA AÇIKGÖZ, İSMAİL İŞLEK & KEMAL BAYSAL. (2008) Charcoal haemoperfusion in Amitriptyline poisoning: Experience in 20 children. Nephrology 13:3, pages 193-197.
Crossref
Darren M Roberts & Nick A Buckley. (2007) Pharmacokinetic Considerations in Clinical Toxicology. Clinical Pharmacokinetics 46:11, pages 897-939.
Crossref
Hüseyin Çaksen, Sinan Akbayram, Dursun Odabaş, Hanefi Özbek, Mehmet Erol, Cihangir Akgün, Oguz Tuncer & Cahide Yilmaz. (2016) Acute amitriptyline intoxication: an analysis of 44 children. Human & Experimental Toxicology 25:3, pages 107-110.
Crossref
Paul I Dargan, Mark G Colbridge & Alison L Jones. (2005) The Management of Tricyclic Antidepressant Poisoning. Toxicological Reviews 24:3, pages 187-194.
Crossref
D Nicholas Bateman. (2005) Tricyclic Antidepressant Poisoning. Toxicological Reviews 24:3, pages 181-186.
Crossref
E. J. F. Franssen, P. W. A. Kunst, P. M. Bet, R. J. M. Strack van Schijndel, A. C. van Loenen & A. J. Wilhelm. (2003) Toxicokinetics of Nortriptyline and Amitriptyline: Two Case Reports. Therapeutic Drug Monitoring 25:2, pages 248-251.
Crossref
Karin Svens & Åke Ryrfeldt. (2001) A Study of Mechanisms Underlying Amitriptyline-Induced Acute Lung Function Impairment. Toxicology and Applied Pharmacology 177:3, pages 179-187.
Crossref
Karin L. Dahlin, Lena Låstbom, Bo Blomgren & Åke Ryrfeldt. (1997) Acute Lung Failure Induced by Tricyclic Antidepressants. Toxicology and Applied Pharmacology 146:2, pages 309-316.
Crossref
Sergio E. Cerda, Chuanyao Tong, Dwight D. Deal & James C. Eisenach. (1997) A Physiologic Assessment of Intrathecal Amitriptyline in Sheep. Anesthesiology 86:5, pages 1094-1103.
Crossref
A. J. Heath. 1995. Therapeutic Antibodies. Therapeutic Antibodies 89 108 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.