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Journal of Toxicology: Clinical Toxicology Volume 31, 1993 - Issue 2
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Research Article

Clinical Features and Management of Digitalis Poisoning — Rationale for Immunotherapy

Pierre Taboulet Hopital Fernand Widal, Université Paris VII, Paris, France
,
Frederic J. Baud Hopital Fernand Widal, Université Paris VII, Paris, France
&
Chantal Bismuth Hopital Fernand Widal, Université Paris VII, Paris, France
Pages 247-260 | Published online: 25 Sep 2008

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Betty S. Chan, Geoffrey K. Isbister, Margaret O’Leary, Angela Chiew & Nicholas A. Buckley. (2016) Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1). Clinical Toxicology 54:6, pages 488-494.
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B. S. H. Chan & N. A. Buckley. (2014) Digoxin-specific antibody fragments in the treatment of digoxin toxicity. Clinical Toxicology 52:8, pages 824-836.
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. (2005) Abstracts of the European Association of Poisons Centres and Clinical Toxicologists XXV International Congress. Clinical Toxicology 43:5, pages 387-538.
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Michael Eddleston & Hans Persson. (2003) Acute Plant Poisoning and Antitoxin Antibodies. Journal of Toxicology: Clinical Toxicology 41:3, pages 309-315.
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Articles from other publishers (41)

Tejas Naik, Anant Kuchik, Pranav Bhor, Utkarsha Ghanwat, Disha Lamkhade & Sandesh Sande. (2023) Digitalis Historical Background and Current Status. International Journal of Advanced Research in Science, Communication and Technology, pages 173-178.
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Uğur KÜÇÜK, Bahadır KIRILMAZ, H. Fatih AŞGÜN & Ercan AKŞİT. (2022) Digoxin Intoxication. Troia Medical Journal.
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Robert Garnier & Bruno Mégarbane. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology 431 439 .
Mohamed A. Salem, Ahmed Serag, Hesham R. El-Seedi, Dalia I. Hamdan, Shahira M. Ezzat & Ahmed Zayed. 2021. Phytochemistry, the Military and Health. Phytochemistry, the Military and Health 443 479 .
Hooman Arbabian, Hwee Min Lee & Andis Graudins. (2018) Elderly patients with suspected chronic digoxin toxicity: A comparison of clinical characteristics of patients receiving and not receiving digoxin‐Fab. Emergency Medicine Australasia 30:2, pages 242-248.
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A. Fieni & M. Arcade. (2016) Bradycardie sinusale au cours d’une intoxication volontaire au laurier roseSinus bradycardia during Nerium oleander self-poisoning. Annales françaises de médecine d'urgence 7:1, pages 38-41.
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Bruno Mégarbane. 2017. Critical Care Toxicology. Critical Care Toxicology 1 10 .
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Darren M. Roberts, Gamini Gallapatthy, Asunga Dunuwille & Betty S. Chan. (2016) Pharmacological treatment of cardiac glycoside poisoning. British Journal of Clinical Pharmacology 81:3, pages 488-495.
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Bruno Mégarbane. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Bruno Mégarbane. 2016. Critical Care Toxicology. Critical Care Toxicology 1 10 .
H. Haouache & F. Lapostolle. (2015) Antidoti. EMC - Urgenze 19:3, pages 1-14.
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Ariful Basher & Quazi Tarikul Islam. 2015. Clinical Toxinology in Asia Pacific and Africa. Clinical Toxinology in Asia Pacific and Africa 609 631 .
Ariful Basher & Quazi Tarikul Islam. 2013. Clinical Toxinology. Clinical Toxinology 1 19 .
Nicholas J. Johnson, David F. Gaieski, Steven R. Allen, Jeanmarie Perrone & Francis DeRoos. (2012) A Review of Emergency Cardiopulmonary Bypass for Severe Poisoning by Cardiotoxic Drugs. Journal of Medical Toxicology 9:1, pages 54-60.
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Kirilmaz Bahadir, Saygi Serkan, Gungor Hasan, Turk Ugur Onsel, Alioğlu Emin, Akyuz Serdar, Asgun Fatih, Tengiz Istemihan & Ercan Ertugrul. (2012) Digoxin intoxication: An old enemy in modern era. Journal of Geriatric Cardiology 9:3, pages 237-242.
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V. Mazy, L. Rousseau, D. Glorieux & P. Duez. (2012) Manger de la salade n’est pas sans risque : une cause rare d’intoxication digitalique familiale. Journal Européen des Urgences et de Réanimation 24:3, pages 187-190.
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J. F. Cade. 2011. Acute Medicine. Acute Medicine 114 136 .
Hossein Sanaei-Zadeh, Zahra Valian, Nasim Zamani, Hoorvash Farajidana & Babak Mostafazadeh. (2011) Clinical features and successful management of suicidal digoxin toxicity without use of digoxin-specific antibody (Fab) fragments – is it possible?. Tropical Doctor 41:2, pages 108-110.
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Stefano Maffè, Lorenzo Cucchi, Franco Zenone, Cristina Bertoncelli, Federico Beldì, Maria Laura Colombo, Massimo Bielli, Anna Maria Paino, Umberto Parravicini, Paola Paffoni, Pierfranco Dellavesa, Antonello Perucca, Nicolò Franchetti Pardo, Fabiana Signorotti, Claudio Didino & Marco Zanetta. (2009) Digitalis must be banished from the table: a rare case of acute accidental Digitalis intoxication of a whole family. Journal of Cardiovascular Medicine 10:9, pages 727-732.
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Pascal Bilbault, Rachid Oubaassine, Hassene Rahmani, Thomas Lavaux, Vincent Castelain, Philippe Sauder & Francis Schneider. (2009) Emergency step-by-step specific immunotherapy in severe digoxin poisoning: an observational cohort study. European Journal of Emergency Medicine 16:3, pages 145-149.
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Frédéric Lapostolle, Stephen W. Borron, Carine Verdier, Pierre Taboulet, Gilles Guerrier, Frédéric Adnet, Jean-Luc Clemessy, Chantal Bismuth & Frédéric J. Baud. (2008) Digoxin-specific Fab fragments as single first-line therapy in digitalis poisoning. Critical Care Medicine 36:11, pages 3014-3018.
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Frédéric Lapostolle, Stephen W. Borron, Carine Verdier, Fabrice Arnaud, James Couvreur, Bruno Mégarbane, Frédéric Baud & Frédéric Adnet. (2008) Assessment of digoxin antibody use in patients with elevated serum digoxin following chronic or acute exposure. Intensive Care Medicine 34:8, pages 1448-1453.
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B. Mégarbane & F. Baud. (2008) Intossicazioni acute da farmaci. EMC - AKOS - Trattato di Medicina 10:3, pages 1-10.
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B. Mégarbane & F. Baud. (2008) Intoxications médicamenteuses aiguës. EMC - Traité de médecine AKOS 3:2, pages 1-10.
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N. Deye, A. Mohebbi Amoli, B. Cholley & F.-J. Baud. 2008. Échocardiographie Doppler chez le patient en état critique. Échocardiographie Doppler chez le patient en état critique 245 276 .
Jean-Louis VincentB. Mégarbane, N. Deye & F. J. Baud. 2008. Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine 179 189 .
Bruno Mégarbane, Nicolas Deye & Frédéric J. Baud. 2008. Acute Heart Failure. Acute Heart Failure 348 358 .
B. Mégarbane, N. Deye & F. J. Baud. 2008. Intensive Care Medicine. Intensive Care Medicine 179 189 .
FRÉDÉRIC LAPOSTOLLE & STEPHEN W. BORRON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 949 962 .
Darren M Roberts & Nick Buckley. (2006) Antidotes for acute cardenolide (cardiac glycoside) poisoning. Cochrane Database of Systematic Reviews 2010:1.
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Christopher P. Holstege & Stephen Dobmeier. (2005) Cardiovascular Challenges in Toxicology. Emergency Medicine Clinics of North America 23:4, pages 1195-1217.
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David Roberts, David Rees, Jo Howard, Chris Hyde & Susan Brunskill. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
P. Taboulet. (2004) Prise en charge de la fibrillation auriculaire par l?urgentiste. Journal Europ?en des Urgences 17:1, pages 4-14.
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P. Chillet, J.M. Korach, D. Petitpas, N. Vincent, L. Poiron, B. Barbier, M. Boazis & PH. Berger. (2018) Digoxin Poisoning and Anuric Acute Renal Failure: Efficiency of the Treatment Associating Digoxin-Specific Antibodies (Fab) and Plasma Exchanges. The International Journal of Artificial Organs 25:6, pages 538-541.
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Jeffrey R. Tucker. (2000) Toxin-induced cardiovascular emergencies in the pediatric patient. Clinical Pediatric Emergency Medicine 1:3, pages 200-206.
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Vicente L. González Andrés. (2000) Revisión sistemática sobre la efectividad e indicaciones de los anticuerpos antidigoxina en la intoxicación digitálica. Revista Española de Cardiología 53:1, pages 49-58.
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Chantal Bismuth, Stephen W Borron, Frédéric J Baud, Pierre Taboulet & Jean-Michel Scherrmann. (2016) Immunotoxicotherapy: Successes, disappointments and hopes. Human & Experimental Toxicology 16:10, pages 602-608.
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Ch. Bismuth, F. J. Baud, S. W. Borron & J. M. Scherrmann. 1996. Toxicology - From Cells to Man. Toxicology - From Cells to Man 321 332 .
Alan Woolf. (2012) Digitalis Intoxication. Clinical Immunotherapeutics 4:4, pages 312-330.
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