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Research Article

Colorimetric and Gas Chromatographic Procedures for Glycolic Acid in Serum: The Major Toxic Metabolite of Ethylene Glycol

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Pages 397-405 | Published online: 25 Sep 2008

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Darren M. Roberts, Robert S. Hoffman, Jeffrey Brent, Valéry Lavergne, Knut Erik Hovda, William H. Porter, Kenneth E. McMartin & Marc Ghannoum. (2022) The serum glycolate concentration: its prognostic value and its correlation to surrogate markers in ethylene glycol exposures. Clinical Toxicology 60:7, pages 798-807.
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Christina L. Moreau, William Kerns, Christian A. Tomaszewski, Kenneth E. McMartin, S. Ruddy Rose, Marsha D. Ford & Jeffrey Brent. (1998) Glycolate Kinetics and Hemodialysis Clearance in Ethylene Glycol Poisoning. Journal of Toxicology: Clinical Toxicology 36:7, pages 659-666.
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Articles from other publishers (25)

Marc Ghannoum, Sophie Gosselin, Robert S. Hoffman, Valery Lavergne, Bruno Mégarbane, Hossein Hassanian-Moghaddam, Maria Rif, Siba Kallab, Steven Bird, David M. Wood, Darren M. Roberts, Badria Alhatali, Kurt Anseeuw, Ingrid Berling, Josée Bouchard, Timothy E. Bunchman, Diane P. Calello, Paul K. Chin, Kent Doi, Tais Galvao, David S. Goldfarb, Lotte C. G. Hoegberg, Sofia Kebede, Jan T. Kielstein, Andrew Lewington, Yi Li, Etienne M. Macedo, Rob MacLaren, James B. Mowry, Thomas D. Nolin, Marlies Ostermann, Ai Peng, Jean-Philippe Roy, Greene Shepherd, Anitha Vijayan, Steven J. Walsh, Anselm Wong & Christopher Yates. (2023) Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup. Critical Care 27:1.
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A.W. Jones, F. Musshoff, T. Krämer, A. E. Steuer, D. Gerostamoulos, O.H. Drummer, G. Drasch, M. Balikova, J. Beyer, H. Teixeira, M. Thevis, W. Schänzer, H. Druid & G. Skopp. 2022. Handbook of Forensic Medicine. Handbook of Forensic Medicine 1167 1312 .
Víctor Pérez Medina Martínez, Carlos Eduardo Espinosa de la Garza, Antonio Germán Hernández-García & Néstor O. Pérez. (2020) Detection and quantification of leached ethylene glycol in biopharmaceuticals by RP-UHPLC. Analytical and Bioanalytical Chemistry 412:8, pages 1795-1806.
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Daniel Sejer Pedersen, Patrick Bélanger, Mikael Frykman, Kirsten Andreasen, Danielle Goudreault, Henrik Pedersen, Peter Hindersson & Torben Breindahl. (2019) Ethylene glycol: Evidence of glucuronidation in vivo shown by analysis of clinical toxicology samples . Drug Testing and Analysis 11:7, pages 1094-1108.
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Hua-Yin Zhang, Ping-Ping Zhang, Xiao-Xin Tan, Ze-Ze Wang, Kao-Qi Lian, Xiang-Dong Xu & Wei-Jun Kang. (2018) Derivatization method for the quantification of lactic acid in cell culture media via gas chromatography and applications in the study of cell glycometabolism. Journal of Chromatography B 1090, pages 1-6.
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James Robson, Stephen Townsend, Paul Bowdler & Kevin C. Honeychurch. (2018) Direct thermal desorption gas chromatographic determination of toxicologically relevant concentrations of ethylene glycol in whole blood. The Analyst 143:4, pages 963-969.
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Adrien Chétioui, Alexis Pillant, Patricia Rullier, Mustapha Sebbane & Amadou Konaté. (2017) Intoxication à l’éthylène-glycol et ivresse aiguë : la prise concomitante d’un poison et de son antidote. Anesthésie & Réanimation 3:2, pages 186-188.
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Kelly W. Hall. 2015. Hamilton & Hardy's Industrial Toxicology. Hamilton & Hardy's Industrial Toxicology 419 444 .
Laurent Imbert, Elodie Saussereau & Christian Lacroix. (2014) Analysis of Eight Glycols in Serum Using LC-ESI–MS-MS. Journal of Analytical Toxicology 38:9, pages 676-680.
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Alan Wayne Jones, Frank Musshoff, Thomas Kraemer, Andrea E. Schwaninger, Dimitri Gerostamoulos, Olaf H. Drummer, Gustav Drasch, Marie A. Balíková, Jochen Beyer, Helena Teixeira, Mario Thevis & Wilhelm Schänzer. 2014. Handbook of Forensic Medicine. Handbook of Forensic Medicine 900 993 .
Petr Kubáň, Pavol Ďurč, Miroslava Bittová & František Foret. (2014) Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection. Journal of Chromatography A 1325, pages 241-246.
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Koen Poesen, Simon Degandt, Juul Boes, Florent Vanstapel, Koen Desmet & Pieter Vermeersch. (2012) Interference of ethylene glycol with lactate measurement: A comparison study on new generation cassette-based blood gas analyzers. Clinica Chimica Acta 414, pages 18-19.
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William H. Porter. (2012) Ethylene glycol poisoning: Quintessential clinical toxicology; analytical conundrum. Clinica Chimica Acta 413:3-4, pages 365-377.
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Loralie Langman, Laura Bechtel & Christopher P. Holstege. 2012. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 1109 1188 .
Yu-Cai He, You-Yan Liu, Cui-Luan Ma & Jian-He Xu. (2011) Modified ferric hydroxamate spectrophotometry for assaying glycolic acid from the hydrolysis of glycolonitrile by Rhodococcus sp. CCZU10-1. Biotechnology and Bioprocess Engineering 16:5, pages 901-907.
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Heather E. Connally, Mary Anna Thrall & Dwayne W. Hamar. (2010) Safety and efficacy of high-dose fomepizole compared with ethanol as therapy for ethylene glycol intoxication in cats. Journal of Veterinary Emergency and Critical Care 20:2, pages 191-206.
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Jean-Pierre Anger, Henri Malandain & Anne Nicolas. (2006) Glycols et ?thers de glycols. EMC - Biologie M?dicale 1:1, pages 1-11.
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Albert D. Fraser. (2002) Clinical Toxicologic Implications of Ethylene Glycol and Glycolic Acid Poisoning. Therapeutic Drug Monitoring 24:2, pages 232-238.
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Karen Pien, Bruno van Vlem, Rudy van Coster, Georges Dacremont & Michel Piette. (2002) An Inherited Metabolic Disorder Presenting as Ethylene Glycol Intoxication in a Young Adult. The American Journal of Forensic Medicine and Pathology 23:1, pages 96-100.
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L. H. Couch & P. C. Howard. (2002) Quantification of glycolic acid in cosmetic products using reversed phase high performance liquid chromatography. International Journal of Cosmetic Science 24:2, pages 89-95.
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Sylvie Saivin, Michel Lavit & Georges Houin. (2000) Les glycols. Revue Française des Laboratoires 2000:322, pages 65-69.
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Jeffrey Brent, Kenneth McMartin, Scott Phillips, Keith K. Burkhart, J. Ward Donovan, Melanie Wells & Ken Kulig. (1999) Fomepizole for the Treatment of Ethylene Glycol Poisoning. New England Journal of Medicine 340:11, pages 832-838.
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Daniel P. Davis, Kenneth J. Bramwell, Robert S. Hamilton & Saralyn R. Williams. (1997) Ethylene glycol poisoning: Case report of a record-high level and a review. The Journal of Emergency Medicine 15:5, pages 653-667.
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M. Roth. 1997. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists.
Howard Wine, Daniel Savitt & J. Gary Abuelo. (2007) Poisonings & Intoxications. Seminars in Dialysis 7:5, pages 338-345.
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