Advanced search
Publication Cover
Journal of Toxicology: Clinical Toxicology Volume 35, 1997 - Issue 3
Journal homepage
260
Views
70
CrossRef citations to date
0
Altmetric
Research Article

Citalopram Overdose-Review of Cases Treated in Swedish Hospitals

Mark Personne The Swedish Poisons Information Centre, Karolinska Hospital, Stockholm, Sweden
,
Gunilla Sjöberg The Swedish Poisons Information Centre, Karolinska Hospital, Stockholm, Sweden
&
Hans Person The Swedish Poisons Information Centre, Karolinska Hospital, Stockholm, Sweden
Pages 237-240 | Published online: 25 Sep 2008

Citations (70)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

. (2016) 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 24-27 May, 2016, Madrid, Spain. Clinical Toxicology 54:4, pages 344-519.
Read now
Pamela L Smithburger, Amy L Seybert, Michael J Armahizer & Sandra L Kane-Gill. (2010) QT prolongation in the intensive care unit: commonly used medications and the impact of drug–drug interactions. Expert Opinion on Drug Safety 9:5, pages 699-712.
Read now
Zeynep Yilmaz, Alessandro Ceschi, Christine Rauber-Lüthy, Oliver Sauer, Uwe Stedtler, Dagmar Prasa, Carola Seidel, Elisabeth Hackl, Petra Hoffmann-Walbeck, Gabriela Gerber-Zupan, Kathrin Bauer, Hugo Kupferschmidt, Gerd-Achim Kullak-Ublick & Martin Wilks. (2010) Escitalopram causes fewer seizures in human overdose than citalopram. Clinical Toxicology 48:3, pages 207-212.
Read now
Joel S. Holger, Kristin M. Engebretsen & John J. Marini. (2009) High dose insulin in toxic cardiogenic shock. Clinical Toxicology 47:4, pages 303-307.
Read now
Lewis S. Nelson, Andrew R. Erdman, Lisa L. Booze, Daniel J. Cobaugh, Peter A. Chyka, Alan D. Woolf, Elizabeth J. Scharman, Paul M. Wax, Anthony S. Manoguerra, Gwenn Christianson, E. Martin Caravati & William G. Troutman. (2007) Selective serotonin reuptake inhibitor poisoning: An evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology 45:4, pages 315-332.
Read now
Lawrence N. Masullo, Michael A. Miller, S. David Baker, Sudip Bose & Marc Levsky. (2006) Clinical Course and Toxicokinetic Data Following Isolated Citalopram Overdose in an Infant. Clinical Toxicology 44:2, pages 165-168.
Read now
Geoffrey K. Isbister, Steven J. Bowe, Andrew Dawson & Ian M. Whyte. (2004) Relative Toxicity of Selective Serotonin Reuptake Inhibitors (SSRIs) in Overdose. Journal of Toxicology: Clinical Toxicology 42:3, pages 277-285.
Read now
C. A. Kelly, N. Dhaun, W. J. Laing, F. E. Strachan, A. M. Good & D. N. Bateman. (2004) Comparative Toxicity of Citalopram and the Newer Antidepressants After Overdose. Journal of Toxicology: Clinical Toxicology 42:1, pages 67-71.
Read now

Articles from other publishers (62)

Ruitong Chen, Farbod Amirghasemi, Haozheng Ma, Victor Ong, Ava Tran & Maral P. S. Mousavi. (2023) Toward Personalized Treatment of Depression: An Affordable Citalopram Test based on a Solid-Contact Potentiometric Electrode for at-Home Monitoring of the Antidepressant Dosage. ACS Sensors 8:10, pages 3943-3951.
Crossref
Aleksandra Babulovska, Daniela Caparovska, Vesna Velikj Stefanovska, Natasha Simonovska, Zanina Pereska, Lidija Petkovska, Kristin Kostadinoski & Kiril Naumoski. (2023) Comparison of rhabdomyolysis in acutely intoxicated patients with psychotropic and chemical substances. Folia Medica 65:3, pages 407-414.
Crossref
Fatemeh Dalayi, Leila Hajiaghababaei, Alireza Badiei, Elham Boorboor Azimi, Mohammad Reza Ganjali & Ghodsi Mohammadi Ziarani. (2019) Tris (2-aminoethyl) Amine Functionalized Nanoporous Silica SBA-15 as a Potential Drug Carrier for Citalopram. International Journal of Basic Science in Medicine 4:4, pages 155-162.
Crossref
Rachel F. Schult, Anna J. Morris, Lindsey Picard & Timothy J. Wiegand. (2019) Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient. The American Journal of Emergency Medicine 37:10, pages 1993.e5-1993.e6.
Crossref
G.H. Ragab & E.A. Bahgat. (2019) Development of bioanalytical HPLC method for simultaneous determination of the antialzhiemer, donepezil hydrochloride and the antidepressant, citalopram hydrobromide in raw materials, spiked human plasma and tablets dosage form. Annales Pharmaceutiques Françaises 77:2, pages 112-120.
Crossref
Darinka Purg, Andrej Markota, Damjan Grenc & Andreja Sinkovič. (2016) Low-dose intravenous lipid emulsion for the treatment of severe quetiapine and citalopram poisoning. Archives of Industrial Hygiene and Toxicology 67:2, pages 164-166.
Crossref
Thomas RE Barnes, Verity C Leeson, Carol Paton, Céire Costelloe, Judit Simon, Noemi Kiss, David Osborn, Helen Killaspy, Tom KJ Craig, Shôn Lewis, Patrick Keown, Shajahan Ismail, Mike Crawford, David Baldwin, Glyn Lewis, John Geddes, Manoj Kumar, Rudresh Pathak & Simon Taylor. (2016) Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial. Health Technology Assessment 20:29, pages 1-46.
Crossref
Erik P. Kraai & Steven A. Seifert. (2014) Citalopram Overdose: a Fatal Case. Journal of Medical Toxicology 11:2, pages 232-236.
Crossref
Rajesh R. Tampi, Michael Balderas, Kathleen V. Carter, Deena J. Tampi, Marian Moca, Amy Knudsen & Jacquelyn May. (2015) Citalopram, QTc Prolongation, and Torsades de Pointes. Psychosomatics 56:1, pages 36-43.
Crossref
Athena K. Petrides, Joshua Moskowitz, Kamisha L. Johnson-Davis, Paul J. Jannetto, Loralie J. Langman, William Clarke & Mark A. Marzinke. (2014) The development and validation of a turbulent flow-liquid chromatography–tandem mass spectrometric method for the simultaneous quantification of citalopram, sertraline, bupropion and hydroxybupropion in serum. Clinical Biochemistry 47:15, pages 73-79.
Crossref
Christopher Kogut, Ericka Breden Crouse, W. Victor R. Vieweg, Mehrul Hasnain, Adrian Baranchuk, Geneviève C. Digby, Jayanthi N. Koneru, Antony Fernandez, Anand Deshmukh, Jules C. Hancox & Ananda K. Pandurangi. (2013) Selective serotonin reuptake inhibitors and torsade de pointes : new concepts and new directions derived from a systematic review of case reports . Therapeutic Advances in Drug Safety 4:5, pages 189-198.
Crossref
Derrick D. Lung, Alan H.B. Wu & Roy R. Gerona. (2013) Cardiotoxicity in a Citalopram and Olanzapine Overdose. The Journal of Emergency Medicine 45:4, pages 554-558.
Crossref
Susan M. Schreffler, Jeanna M. Marraffa, Christine M. Stork & Jennifer Mackey. (2013) Sodium Channel Blockade With QRS Widening After an Escitalopram Overdose. Pediatric Emergency Care 29:9, pages 998-1001.
Crossref
M. J. Cooke & W. S. Waring. (2012) Citalopram and cardiac toxicity. European Journal of Clinical Pharmacology 69:4, pages 755-760.
Crossref
Shane Darke, Michelle Torok & Johan Duflou. (2012) Contributory and Incidental Blood Concentrations in Deaths Involving Citalopram. Journal of Forensic Sciences 58:2, pages 432-435.
Crossref
Joseph K. Maddry, Klementyna Breyer, Kelly M. Cook & Kennon Heard. (2013) Monomorphic ventricular tachycardia after intentional citalopram overdose. The American Journal of Emergency Medicine 31:2, pages 447.e5-447.e8.
Crossref
Senthil Nachimuthu, Manish D. Assar & Jeffrey M. Schussler. (2012) Drug-induced QT interval prolongation: mechanisms and clinical management. Therapeutic Advances in Drug Safety 3:5, pages 241-253.
Crossref
Derrick Lung, Kelly Yeh & Charlene Kiang. (2012) Delayed, Fatal Cardiotoxicity Associated With Bupropion and Citalopram Overdose. Journal of Clinical Psychopharmacology 32:3, pages 431-434.
Crossref
Jon B. Cole, Samuel J. Stellpflug, Eric A. Gross & Stephen W. Smith. (2011) Wide Complex Tachycardia in a Pediatric Diphenhydramine Overdose Treated With Sodium Bicarbonate. Pediatric Emergency Care 27:12, pages 1175-1177.
Crossref
T. Zilker. (2010) Intoxikationen als Ursachen von BewusstseinsstörungenPoisoning as cause of disturbance of consciousness. Intensivmedizin und Notfallmedizin 47:2, pages 101-108.
Crossref
W. Stephen Waring, Julie A. Gray & Ann Graham. (2008) Predictive factors for generalized seizures after deliberate citalopram overdose. British Journal of Clinical Pharmacology 66:6, pages 861-865.
Crossref
Alexander M. ScharkoJeremy Schumacher. (2008) Prolonged QTc Interval in a 14-Year-Old Girl with Escitalopram Overdose. Journal of Child and Adolescent Psychopharmacology 18:3, pages 297-298.
Crossref
Asim F. Tarabar, Robert S. Hoffman & Lewis S. Nelson. (2008) Citalopram overdose: Late presentation of torsades de pointes (TdP) with cardiac arrest. Journal of Medical Toxicology 4:2, pages 101-105.
Crossref
Erica L. Liebelt. (2008) An Update on Antidepressant Toxicity: An Evolution of Unique Toxicities to Master. Clinical Pediatric Emergency Medicine 9:1, pages 24-34.
Crossref
Robert J. Flanagan. (2008) Fatal toxicity of drugs used in psychiatry. Human Psychopharmacology: Clinical and Experimental 23:S1, pages S43-S51.
Crossref
Geoffrey K. Isbister, Lena E. Friberg, Barrie Stokes, Nicholas A. Buckley, Christopher Lee, Naren Gunja, Simon G. Brown, Ellen MacDonald, Andis Graudins, Anna Holdgate & Stephen B. Duffull. (2007) Activated Charcoal Decreases the Risk of QT Prolongation After Citalopram Overdose. Annals of Emergency Medicine 50:5, pages 593-600.e46.
Crossref
Tracey H. Reilly & Mark A. Kirk. (2007) Atypical Antipsychotics and Newer Antidepressants. Emergency Medicine Clinics of North America 25:2, pages 477-497.
Crossref
WESLEY PALATNICK. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 549 559 .
Geoffrey K. Isbister, Lena E. Friberg & Stephen B. Duffull. (2006) Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdose. Intensive Care Medicine 32:7, pages 1060-1065.
Crossref
Duccio Luchini, Giovanna Morabito & Fabio Centini. (2005) Case Report of a Fatal Intoxication by Citalopram. American Journal of Forensic Medicine & Pathology 26:4, pages 352-354.
Crossref
J. Guy Edwards. (2018) Newer v . older antidepressants in long-term pharmacotherapy: Revisiting… Prevention of relapse and recurrence of depression . Advances in Psychiatric Treatment 11:3, pages 184-194.
Crossref
S L Greene, P I Dargan & A L Jones. (2005) Acute poisoning: understanding 90% of cases in a nutshell. Postgraduate Medical Journal 81:954, pages 204-216.
Crossref
Peter John Cuenca, Kurtis Rex Holt & Jeffrey David Hoefle. (2004) Seizure secondary to citalopram overdose. The Journal of Emergency Medicine 26:2, pages 177-181.
Crossref
Kristin M Engebretsen, Carson R Harris & James E Wood. (2003) Cardiotoxicity and late onset seizures with citalopram overdose. The Journal of Emergency Medicine 25:2, pages 163-166.
Crossref
Michael A. Crouch, Lynn Limon & Angela T. Cassano. (2012) Clinical Relevance and Management of Drug‐Related QT Interval Prolongation. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 23:7, pages 881-908.
Crossref
Abbas Pousti, Golrokh Malihi & Bijan Naghibi. (2002) Effect of citalopram on ouabain‐induced arrhythmia in isolated guinea‐pig atria. Human Psychopharmacology: Clinical and Experimental 18:2, pages 121-124.
Crossref
Harry J. Witchel, Jules C. Hancox & David J. Nutt. (2003) Psychotropic Drugs, Cardiac Arrhythmia, and Sudden Death. Journal of Clinical Psychopharmacology 23:1, pages 58-77.
Crossref
Fredrik C. Kugelberg, Björn Carlsson, Johan Ahlner & Finn Bengtsson. (2003) Stereoselective single‐dose kinetics of citalopram and its metabolites in rats. Chirality 15:7, pages 622-629.
Crossref
Alexander Fisher, Michael Davis, James Croft-Baker, Patrick Purcell & Allan McLean. (2012) Citalopram-Induced Severe Hyponatraemia with Coma and Seizure. Adverse Drug Reactions and Toxicological Reviews 21:4, pages 179-187.
Crossref
Nicole AnastosIain M. McIntyreMatthew J. LynchOlaf H. Drummer. (2002) Postmortem Concentrations of Citalopram. Journal of Forensic Sciences 47:4, pages 15458J.
Crossref
Fredrik C. Kugelberg, Gustav Apelqvist & Finn Bengtsson. (2002) Effects of Chronic Citalopram Treatment on Central and Peripheral Spontaneous Open-Field Behaviours in Rats. Pharmacology & Toxicology 90:6, pages 303-310.
Crossref
Birgitta Jonasson & Tom Saldeen. (2002) Citalopram in fatal poisoning cases. Forensic Science International 126:1, pages 1-6.
Crossref
Francesco Pisani, Giancarla Oteri, Cinzia Costa, Giorgio Di Raimondo & Raoul Di Perri. (2002) Effects of Psychotropic Drugs on Seizure Threshold. Drug Safety 25:2, pages 91-110.
Crossref
G. Laux, A. Eckert, W. E. Müller, U. Breyer-Pfaff, S. Kasper, M. Riedel, N. Müller, H. J. Möller, C. Hiemke, C. Schöchlin & R. R. Engel. 2002. Neuro-Psychopharmaka Ein Therapie-Handbuch. Neuro-Psychopharmaka Ein Therapie-Handbuch 223 363 .
Geoffrey K Isbister, Felicity H Prior & Aidan Foy. (2016) Citalopram-Induced Bradycardia and Presyncope. Annals of Pharmacotherapy 35:12, pages 1552-1555.
Crossref
. 2001. Dreisbach's Handbook of Poisoning. Dreisbach's Handbook of Poisoning 508 531 .
Ian M. Anderson & J. Guy Edwards. (2018) Guidelines for choice of selective serotonin reuptake inhibitor in depressive illness. Advances in Psychiatric Treatment 7:3, pages 170-180.
Crossref
Glenn Catalano, Maria C. Catalano, Melissa A. Epstein & Petros E. Tsambiras. (2001) QTc Interval Prolongation Associated with Citalopram Overdose: A Case Report and Literature Review. Clinical Neuropharmacology 24:3, pages 158-162.
Crossref
Fredrik C Kugelberg, Gustav Apelqvist, Björn Carlsson, Johan Ahlner & Finn Bengtsson. (2009) In vivo steady‐state pharmacokinetic outcome following clinical and toxic doses of racemic citalopram to rats . British Journal of Pharmacology 132:8, pages 1683-1690.
Crossref
Majed Odeh, Arie Oliven & Ahuva Beny. (2001) Severe Symptomatic Hyponatremia during Citalopram Therapy. The American Journal of the Medical Sciences 321:2, pages 159-160.
Crossref
John Sarko. (2000) ANTIDEPRESSANTS, OLD AND NEW. Emergency Medicine Clinics of North America 18:4, pages 637-654.
Crossref
Michael J. Robinson & James L. Levenson. (2000) The use of psychotropics in the medically ill. Current Psychiatry Reports 2:3, pages 247-255.
Crossref
Joseph F. Goldberg. (2000) NEW DRUGS IN PSYCHIATRY. Emergency Medicine Clinics of North America 18:2, pages 211-231.
Crossref
Pál Pacher, Zsolt Bagi, Zoltán Lakó-Futó, Zoltán Ungvári, Péter P. Nánási & Valéria Kecskeméti. (2000) Cardiac electrophysiological effects of citalopram in guinea pig papillary muscle Comparison with clomipramine. General Pharmacology: The Vascular System 34:1, pages 17-23.
Crossref
F Musshoff, P Schmidt & B Madea. (1999) Fatality caused by a combined trimipramine–citalopram intoxication. Forensic Science International 106:2, pages 125-131.
Crossref
Francesco Pisani, Edoardo Spina & Giancarla Oteri. (1999) Antidepressant Drugs and Seizure Susceptibility: From In Vitro Data to Clinical Practice. Epilepsia 40:s10, pages s48-s56.
Crossref
Søren Lind Rasmussen, Kerstin F. Overø & Per Tanghøj. (1999) Cardiac Safety of Citalopram: Prospective Trials and Retrospective Analyses. Journal of Clinical Psychopharmacology 19:5, pages 407-415.
Crossref
Jennifer Y. Tan & Gary M. Levin. (2012) Citalopram in the Treatment of Depression and Other Potential Uses in Psychiatry. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 19:6, pages 675-689.
Crossref
S. Bejerot & O. Bodlund. (1998) Response to high doses of citalopram in treatment-resistant obsessive-compulsive disorder. Acta Psychiatrica Scandinavica 98:5, pages 423-424.
Crossref
A Fromajoux, P Saviuc, V Danel & F Vincent. (1998) Toxicité cardiaque du citalopram lors d'une ingestion volontaire aiguë. Réanimation Urgences 7:5, pages 585-588.
Crossref
Burton J. Goldstein & Paul J Goodnick. (2016) Selective serotonin reuptake inhibitors in the treatment of affective disorders—III. Tolerability, safety and pharmacoeconomics. Journal of Psychopharmacology 12:4_suppl, pages 55-S87.
Crossref
Mark Personne, Hans Persson & Gunilla Sjöberg. (1997) Citalopram toxicity. The Lancet 350:9076, pages 518-519.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.