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Case Reports

Methotrexate toxicity presenting as cutaneous ulcerations on psoriatic plaques

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Pages 333-335 | Received 06 Jan 2013, Accepted 19 Feb 2013, Published online: 28 Mar 2013

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Nupur Parnami, Tarun Garg, Goutam Rath & Amit K. Goyal. (2014) Development and characterization of nanocarriers for topical treatment of psoriasis by using combination therapy. Artificial Cells, Nanomedicine, and Biotechnology 42:6, pages 406-412.
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Sahim Aziz Hazari, Harsimran Kaur, Ritu Karwasra, Mohammed A.S. Abourehab, Asim Ali Khan & Prashant Kesharwani. (2023) An overview of topical lipid-based and polymer-based nanocarriers for treatment of psoriasis. International Journal of Pharmaceutics 638, pages 122938.
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Shelly Rivas & Allireza Alloo. 2022. Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology. Interdisciplinary Approaches to Overlap Disorders in Dermatology & Rheumatology 271 281 .
Ismaiel A. Tekko, Andi Dian Permana, Lalitkumar Vora, Taher Hatahet, Helen O. McCarthy & Ryan F. Donnelly. (2020) Localised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis. European Journal of Pharmaceutical Sciences 152, pages 105469.
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Mahdiyeh Bahramizadeh, Maryam Bahramizadeh, Bita Kiafar, Amir Hossein Jafarian, Amin Reza Nikpoor, Mahdi Hatamipour, Habibollah Esmaily, Zari Rezaeemehr, Shiva Golmohammadzadeh, Seyedeh Alia Moosavian & Mahmoud Reza Jafari. (2019) Development, characterization and evaluation of topical methotrexate-entrapped deformable liposome on imiquimod-induced psoriasis in a mouse model. International Journal of Pharmaceutics 569, pages 118623.
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Abdulaziz M. Al-mahallawi, Ahmed R. Fares & Wessam H. Abd-Elsalam. (2019) Enhanced Permeation of Methotrexate via Loading into Ultra-permeable Niosomal Vesicles: Fabrication, Statistical Optimization, Ex Vivo Studies, and In Vivo Skin Deposition and Tolerability. AAPS PharmSciTech 20:5.
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Zeineb Alaya, Sana Mokni, Marwa Guerfala, Chaker Ben Salem, Badreddine Sriha, Rafiaa Nouira & Elyès Bouajina. (2018) Acute severe cutaneous methotrexate toxicity in a patient with rheumatoid arthritis: Report of a rare side effect. The Egyptian Rheumatologist 40:4, pages 281-284.
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Paula Valentina Estrada Alarcon, Silvia García-Díaz, Marta Oña & Hèctor Corominas. (2015) Superficial Tissue Necrosis Related to Methotrexate Injection in a Patient With Rheumatoid Arthritis. JCR: Journal of Clinical Rheumatology 21:7, pages 370.
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Julie Delyon, Nicolas Ortonne, Emmanuel Benayoun, Julien Moroch, Pierre Wolkenstein, Emilie Sbidian & Olivier Chosidow. (2015) Low-dose methotrexate-induced skin toxicity: Keratinocyte dystrophy as a histologic marker. Journal of the American Academy of Dermatology 73:3, pages 484-490.
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. (2013) Methotrexate. Reactions Weekly 1470:1, pages 30-30.
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