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The World Journal of Biological Psychiatry Volume 13, 2012 - Issue 1
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Research Article

Multiscale assessment of treatment efficacy in adults with ADHD: A randomized placebo-controlled, multi-centre study with extended-release methylphenidate

Wolfgang RetzNeurocentre, Saarland University Hospital, University of the Saarland, Homburg, GermanyCorrespondence[email protected]
,
Michael RöslerNeurocentre, Saarland University Hospital, University of the Saarland, Homburg, Germany
,
Claudia OseInstitute for Medical Informatics, Biometry and Epidemiology, University Essen, Essen, Germany
,
André ScheragInstitute for Medical Informatics, Biometry and Epidemiology, University Essen, Essen, Germany
,
Barbara AlmCentral Institute of Mental Health, Mannheim, Germany
,
Alexandra PhilipsenDepartment of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
,
Roland FischerMedice, Arzneimittel Pütter GmbH & Co.KG, Iserlohn, Germany
,
Richard AmmerMedice, Arzneimittel Pütter GmbH & Co.KG, Iserlohn, Germany
& The Study Group show all
Pages 48-59 | Received 16 Aug 2010, Published online: 14 Dec 2010

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Giulio Emilio Brancati, Donatella Acierno, Margherita Barbuti, Camilla Elefante, Samuele Gemignani, Accursio Raia & Giulio Perugi. (2023) Revisiting stimulant use for emotional dysregulation in attention-deficit/hyperactivity disorder (ADHD). Expert Review of Neurotherapeutics 23:11, pages 981-994.
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Lisa L Weyandt, Danielle R Oster, Marisa E Marraccini, Bergljot Gyda Gudmundsdottir, Bailey A Munro, Brynheld Martinez Zavras & Ben Kuhar. (2014) Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants. Psychology Research and Behavior Management 7, pages 223-249.
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Louis S Matza, Mary K Devine, Virginia Sutton Haynes, Evan W Davies, Jacqueline M Kostelec, Foula Televantou & Jessica B Jordan. (2014) Health state utilities associated with adult attention-deficit/hyperactivity disorder. Patient Preference and Adherence 8, pages 997-1006.
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Narong Maneeton, Benchalak Maneeton, Sirijit Suttajit, Jirayu Reungyos, Manit Srisurapanont & Stephen D Martin. (2014) Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD. Drug Design, Development and Therapy 8, pages 1685-1693.
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Josep Antoni Ramos-Quiroga, Viviana Nasillo, Fernando Fernández-Aranda & Miguel Casas. (2014) Addressing the lack of studies in attention-deficit/hyperactivity disorder in adults. Expert Review of Neurotherapeutics 14:5, pages 553-567.
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Wolfgang Retz, Rolf-Dieter Stieglitz, Salvatore Corbisiero, Petra Retz-Junginger & Michael Rösler. (2012) Emotional dysregulation in adult ADHD: what is the empirical evidence?. Expert Review of Neurotherapeutics 12:10, pages 1241-1251.
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Articles from other publishers (48)

Siham Albesisi & Paul G. Overton. (2023) Relationship Between ADHD-Like Traits and Emotion Dysregulation in the Adult General Population. Advances in Neurodevelopmental Disorders.
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José Ramón Gutiérrez-Casares, Cristina Segú-Vergés, Juncal Sabate Chueca, Tamara Pozo-Rubio, Mireia Coma, Carmen Montoto & Javier Quintero. (2023) In silico evaluation of the role of lisdexamfetamine on attention-deficit/hyperactivity disorder common psychiatric comorbidities: mechanistic insights on binge eating disorder and depression. Frontiers in Neuroscience 17.
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José Ramón Gutiérrez-Casares, Javier Quintero, Cristina Segú-Vergés, Pilar Rodríguez Monterde, Tamara Pozo-Rubio, Mireia Coma & Carmen Montoto. (2023) In silico clinical trial evaluating lisdexamfetamine’s and methylphenidate’s mechanism of action computational models in an attention-deficit/hyperactivity disorder virtual patients’ population. Frontiers in Psychiatry 14.
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Iman Idrees, Alessio Bellato, Samuele Cortese & Madeleine J. Groom. (2023) The effects of stimulant and non-stimulant medications on the autonomic nervous system (ANS) functioning in people with ADHD: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 144, pages 104968.
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Craig B. H. Surman & Daniel M. Walsh. (2022) Do Treatments for Adult ADHD Improve Emotional Behavior? A Systematic Review and Analysis. Journal of Attention Disorders 26:14, pages 1822-1832.
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Constantin-Cristian Topriceanu, James C. Moon, Gabriella Captur & Bhathika Perera. (2022) The use of attention-deficit hyperactivity disorder medications in cardiac disease. Frontiers in Neuroscience 16.
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Philip Asherson, Lena Johansson, Rachel Holland, Megan Bedding, Andrew Forrester, Laura Giannulli, Ylva Ginsberg, Sheila Howitt, Imogen Kretzschmar, Stephen Lawrie, Craig Marsh, Caroline Kelly, Megan Mansfield, Clare McCafferty, Khuram Khan, Ulrich Müller-Sedgwick, John Strang, Grace Williamson, Lauren Wilson, Susan Young, Sabine Landau & Lindsay Thomson. (2022) OROS-methylphenidate to reduce ADHD symptoms in male prisoners aged 16–25 years: a RCT. Efficacy and Mechanism Evaluation 9:6, pages 1-114.
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Kim Boesen, Asger Sand Paludan-Müller, Peter C Gøtzsche & Karsten Juhl Jørgensen. (2022) Extended-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database of Systematic Reviews 2022:2.
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Wolfgang Retz. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 2465 2486 .
Michael Rösler, Wolfgang Retz & Daniel Turner. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 4543 4560 .
Maayan Ben-Dor Cohen, Eran Eldar, Adina Maeir & Mor Nahum. (2021) Emotional dysregulation and health related quality of life in young adults with ADHD: a cross sectional study. Health and Quality of Life Outcomes 19:1.
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Danfeng Yuan, Manxue Zhang, Yan Huang, Xinwei Wang, Jian Jiao & Yi Huang. (2021) Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD. Medicine 100:46, pages e27858.
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Wolfgang Retz. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 23 .
Michael Rösler, Wolfgang Retz & Daniel Turner. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 18 .
Jesse Elliott, Amy Johnston, Don Husereau, Shannon E. Kelly, Caroline Eagles, Alice Charach, Shu-Ching Hsieh, Zemin Bai, Alomgir Hossain, Becky Skidmore, Eva Tsakonas, Dagmara Chojecki, Muhammad Mamdani & George A. Wells. (2020) Pharmacologic treatment of attention deficit hyperactivity disorder in adults: A systematic review and network meta-analysis. PLOS ONE 15:10, pages e0240584.
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Wolfgang Retz, Michael Rösler, Roland Fischer, Claudia Ose & Richard Ammer. (2020) Methylphenidate treatment of adult ADHD patients improves the degree of ADHD severity under routine conditions. Journal of Neural Transmission 127:10, pages 1427-1434.
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Gabriele Masi, Pamela Fantozzi, Pietro Muratori, Giulia Bertolucci, Annalisa Tacchi, Arianna Villafranca, Chiara Pfanner & Samuele Cortese. (2020) Emotional dysregulation and callous unemotional traits as possible predictors of short-term response to methylphenidate monotherapy in drug-naïve youth with ADHD. Comprehensive Psychiatry 100, pages 152178.
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W. Retz, P. Retz-Junginger, S. Davydenko & M. Rösler. (2020) Medikamentöse Therapie der Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung im ErwachsenenalterPharmacotherapy of attention deficit hyperactivity disorder in adults. Der Nervenarzt 91:7, pages 583-590.
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Michael Rösler & Wolfgang Retz. (2020) Medikamentöse Therapie der ADHS bei Erwachsenen. PSYCH up2date 14:01, pages 59-75.
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Stefano Pallanti & Luana SalernoStefano Pallanti & Luana Salerno. 2020. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders 61 86 .
Thomas B. Fay & Martin A. Alpert. (2019) Cardiovascular Effects of Drugs Used to Treat Attention-Deficit/Hyperactivity Disorder. Cardiology in Review 27:3, pages 113-121.
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Matej Stuhec, Petar Lukić & Igor Locatelli. (2018) Efficacy, Acceptability, and Tolerability of Lisdexamfetamine, Mixed Amphetamine Salts, Methylphenidate, and Modafinil in the Treatment of Attention-Deficit Hyperactivity Disorder in Adults: A Systematic Review and Meta-analysis. Annals of Pharmacotherapy 53:2, pages 121-133.
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Toivo Zinnow, Tobias Banaschewski, Andreas J. Fallgatter, Carolin Jenkner, Florence Philipp-Wiegmann, Alexandra Philipsen, Wolfgang Retz, Esther Sobanski, Johannes Thome & Michael Rösler. (2018) ESCAlate – Adaptive treatment approach for adolescents and adults with ADHD: study protocol for a randomized controlled trial. Trials 19:1.
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Toivo Zinnow, Tobias Banaschewski, Andreas J. Fallgatter, Carolin Jenkner, Sabina Millenet, Alexandra Philipsen, Wolfgang Retz, Esther Sobanski, Johannes Thome & Michael Rösler. (2018) ESCAlate – Ein adaptiver Behandlungsansatz für Jugendliche und Erwachsene mit ADHS. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 66:4, pages 219-231.
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Lenard A. Adler & Michael J. Silverstein. (2018) Emotional Dysregulation in Adult ADHD. Psychiatric Annals 48:7, pages 318-322.
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Francesca Lenzi, Samuele Cortese, Joseph Harris & Gabriele Masi. (2018) Pharmacotherapy of emotional dysregulation in adults with ADHD: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 84, pages 359-367.
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Michael J. Silverstein, Samuel Alperin, Yonatan Hochstein & Lenard A. Adler. 2018. Moodiness in ADHD. Moodiness in ADHD 161 185 .
Richard Weisler, Lawrence Ginsberg, Bryan Dirks, Patrick Deas, Ben Adeyi & Lenard A. Adler. (2014) Treatment With Lisdexamfetamine Dimesylate Improves Self- and Informant-Rated Executive Function Behaviors and Clinician- and Informant-Rated ADHD Symptoms in Adults: Data From a Randomized, Double-Blind, Placebo-Controlled Study. Journal of Attention Disorders 21:14, pages 1198-1207.
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David R. Coghill, Tobias Banaschewski, César Soutullo, Matthew G. Cottingham & Alessandro Zuddas. (2017) Systematic review of quality of life and functional outcomes in randomized placebo-controlled studies of medications for attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 26:11, pages 1283-1307.
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T.R. Moukhtarian, R.E. Cooper, E. Vassos, P. Moran & P. Asherson. (2020) Effects of stimulants and atomoxetine on emotional lability in adults: A systematic review and meta-analysis. European Psychiatry 44, pages 198-207.
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Rolf-Dieter Stieglitz, Achim Haug, Erdmann Fähndrich, Michael Rösler & Wolfgang Trabert. (2017) Comprehensive Psychopathological Assessment Based on the Association for Methodology and Documentation in Psychiatry (AMDP) System: Development, Methodological Foundation, Application in Clinical Routine, and Research. Frontiers in Psychiatry 8.
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Hsing-Chang Ni, Yu-Ju Lin, Susan Shur-Fen Gau, Hui-Chun Huang & Li-Kuang Yang. (2016) An Open-Label, Randomized Trial of Methylphenidate and Atomoxetine Treatment in Adults With ADHD. Journal of Attention Disorders 21:1, pages 27-39.
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Salvatore Corbisiero, Beatrice Mörstedt, Hannes Bitto & Rolf-Dieter Stieglitz. (2017) Emotional Dysregulation in Adults With Attention-Deficit/Hyperactivity Disorder-Validity, Predictability, Severity, and Comorbidity. Journal of Clinical Psychology 73:1, pages 99-112.
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M. Linden & J. Weddigen. (2016) Teilleistungsstörungen/MCD und ADHS im ErwachsenenalterMinimal cerebral dysfunctions and ADHD in adulthood. Der Nervenarzt 87:11, pages 1175-1184.
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Se-Hoon Shim, Hee-jung Yoon, Jeongjae Bak, Sang-Woo Hahn & Yong-Ku Kim. (2016) Clinical and neurobiological factors in the management of treatment refractory attention-deficit hyperactivity disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 70, pages 237-244.
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Emanuel Bubl, Michael D?rr, Andreas Riedel, Dieter Ebert, Alexandra Philipsen, Michael Bach & Ludger Tebartz van Elst. (2015) Elevated Background Noise in Adult Attention Deficit Hyperactivity Disorder Is Associated with Inattention. PLOS ONE 10:2, pages e0118271.
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Maria Unenge Hallerbäck, Tove Lugnegård & Christopher Gillberg. (2012) ADHD and Nicotine Use in Schizophrenia or Asperger Syndrome. Journal of Attention Disorders 18:5, pages 425-433.
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