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The World Journal of Biological Psychiatry Volume 14, 2013 - Issue 2
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Human endogenous retrovirus type W (HERV-W) in schizophrenia: A new avenue of research at the gene–environment interface

Marion LeboyerAP-HP, Henri Mondor-Albert Chenevier Hospitals, Department of Psychiatry, Creteil, France;INSERM, U 955, Psychiatry Genetic team, Creteil, France;University Paris East, Faculty of Medicine, UMR-S 955, Creteil, France;Fondation fondaMental, French National Science Foundation, Creteil, France
,
Ryad TamouzaImmunology and Histocompatibility Department and INSERM, U 940, Saint-Louis Hospital, Paris, France
,
Dominique CharronImmunology and Histocompatibility Department and INSERM, U 940, Saint-Louis Hospital, Paris, France
,
Raphaél FaucardGeNeuro Innovation, Bioparc Lyon-Laënnec, Lyon, France
&
Hervé PerronEcole Doctorale BMIC, Université Claude Bernard, Lyon, France;GeNeuro Innovation, Bioparc Lyon-Laënnec, Lyon, France;GeNeuro, Plan-Les-Ouates, Geneva, SwitzerlandCorrespondence[email protected]
Pages 80-90 | Received 31 Mar 2011, Accepted 21 Jun 2011, Published online: 22 Sep 2011

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Emanuela Balestrieri, Mariabernarda Pitzianti, Claudia Matteucci, Elisa D’Agati, Roberta Sorrentino, Antonia Baratta, Rosa Caterina, Rossella Zenobi, Paolo Curatolo, Enrico Garaci, Paola Sinibaldi-Vallebona & Augusto Pasini. (2014) Human endogenous retroviruses and ADHD. The World Journal of Biological Psychiatry 15:6, pages 499-504.
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Sofia N. Oskolkova. (2022) Schizophrenia: a Narrative Review of Etiological and Diagnostic Issues. Consortium Psychiatricum 3:3, pages 20-35.
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E. M. Johansson, D. Bouchet, R. Tamouza, P. EllulAS. MorrE. Avignone, R. GermiM. Leboyer, H. PerronL. Groc. (2020) Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis. Science Advances 6:29.
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Balestrieri, Matteucci, Cipriani, Grelli, Ricceri, Calamandrei & Vallebona. (2019) Endogenous Retroviruses Activity as a Molecular Signature of Neurodevelopmental Disorders. International Journal of Molecular Sciences 20:23, pages 6050.
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Ellen Kure Fischer & Antonio Drago. (2017) A molecular pathway analysis stresses the role of inflammation and oxidative stress towards cognition in schizophrenia. Journal of Neural Transmission 124:7, pages 765-774.
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Pierre Ellul, Laurent Groc & Marion Leboyer. (2017) Les rétrovirus endogènes humains, une implication dans la schizophrénie et le trouble bipolaire. médecine/sciences 33:4, pages 404-409.
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Emily G. Severance, Robert H. Yolken & William W. Eaton. (2016) Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling. Schizophrenia Research 176:1, pages 23-35.
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Fang Li & Håkan Karlsson. (2016) Expression and regulation of human endogenous retrovirus W elements. APMIS 124:1-2, pages 52-66.
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Yavuz Ayhan, Ross McFarland & Mikhail V. Pletnikov. (2016) Animal models of gene–environment interaction in schizophrenia: A dimensional perspective. Progress in Neurobiology 136, pages 1-27.
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A. L. Sutterland, G. Fond, A. Kuin, M. W. J. Koeter, R. Lutter, T. van Gool, R. Yolken, A. Szoke, M. Leboyer & L. de Haan. (2015) Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta-analysis . Acta Psychiatrica Scandinavica 132:3, pages 161-179.
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Crossref
David H. Dreyfus. 2015. Infection and Autoimmunity. Infection and Autoimmunity 301 317 .
Mamneet Manghera, Jennifer Ferguson & Renée Douville. (2014) Endogenous Retrovirus-K and Nervous System Diseases. Current Neurology and Neuroscience Reports 14:10.
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Monojit Debnath, Dara M. Cannon & Ganesan Venkatasubramanian. (2013) Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: Associations and functional implications. Progress in Neuro-Psychopharmacology and Biological Psychiatry 42, pages 49-62.
Crossref
K. Bechter. (2013) Updating the mild encephalitis hypothesis of schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 42, pages 71-91.
Crossref
H Perron, N Hamdani, R Faucard, M Lajnef, S Jamain, C Daban-Huard, S Sarrazin, E LeGuen, J Houenou, M Delavest, H Moins-Teisserenc, D Bengoufa, R Yolken, A Madeira, M Garcia-Montojo, N Gehin, I Burgelin, G Ollagnier, C Bernard, A Dumaine, A Henrion, A Gombert, K Le Dudal, D Charron, R Krishnamoorthy, R Tamouza & M Leboyer. (2012) Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder. Translational Psychiatry 2:12, pages e201-e201.
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