8,059
Views
45
CrossRef citations to date
0
Altmetric
Original Investigation

Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review

, &
Pages 622-633 | Received 17 Feb 2015, Accepted 18 Jun 2015, Published online: 30 Jul 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Jakub Hort, Thomas Duning & Robert Hoerr. (2023) Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review. Neuropsychiatric Disease and Treatment 19, pages 647-660.
Read now
Qin Li, Tao Ye, Ting Long & Xuemei Peng. (2019) Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury in a rat model via the TLR4/NF-κB signaling pathway. Bioscience, Biotechnology, and Biochemistry 83:4, pages 675-683.
Read now

Articles from other publishers (43)

Lixia Chen, Yilan Zhen, Xuncui Wang, Jingji Wang & Guoqi Zhu. (2023) Neurovascular glial unit: A target of phytotherapy for cognitive impairments. Phytomedicine 119, pages 155009.
Crossref
Ishak Suat Ovey, Ahmet Ozsimsek, Halil Aziz Velioglu, Ozlem Altay, Adil Mardinoglu & Burak Yulug. (2023) EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line. Frontiers in Cellular Neuroscience 17.
Crossref
Ratree Sawangjit, Chorthip Chuenchom, Thanchanok Sanverm, Nathorn Chaiyakunapruk, Jariya Jiranukool, Rodchares Nithipaijit, Saranrat Sadoyu, Chankiat Phianchana & Peerawat Jinatongthai. (2023) Efficacy and safety of herbal medicine on dementia and cognitive function: An umbrella review of systematic reviews and meta‐analysis. Phytotherapy Research 37:6, pages 2364-2380.
Crossref
Priyadarshi Prajjwal, Mohammed Dheyaa Marsool Marsool, Pugazhendi Inban, Bhavya Sharma, Shahnaz Asharaf, Soumya Aleti, Srikanth Gadam, Ahmed Sermed Al Sakini & Dalia Dhia Hadi. (2023) Vascular dementia subtypes, pathophysiology, genetics, neuroimaging, biomarkers, and treatment updates along with its association with Alzheimer's dementia and diabetes mellitus. Disease-a-Month 69:5, pages 101557.
Crossref
Mehtap Sahiner, Aynur Sanem Yilmaz, Buket Gungor & Nurettin Sahiner. (2023) A Review on Phyto-Therapeutic Approaches in Alzheimer’s Disease. Journal of Functional Biomaterials 14:1, pages 50.
Crossref
Mark Obrenovich, Sandeep Kumar Singh, Yi Li, George Perry, Bushra Siddiqui, Waqas Haq & V. Prakash Reddy. (2022) Natural Product Co-Metabolism and the Microbiota–Gut–Brain Axis in Age-Related Diseases. Life 13:1, pages 41.
Crossref
Žarko Kulić, Martin D. Lehner & Gunnar P. H. Dietz. (2022) Ginkgo biloba leaf extract EGb 761® as a paragon of the product by process concept. Frontiers in Pharmacology 13.
Crossref
José María García-Alberca, Silvia Mendoza & Esther Gris. (2022) Benefits of Treatment with Ginkgo Biloba Extract EGb 761 Alone or Combined with Acetylcholinesterase Inhibitors in Vascular Dementia. Clinical Drug Investigation 42:5, pages 391-402.
Crossref
Jean M. Bokelmann. 2022. Medicinal Herbs in Primary Care. Medicinal Herbs in Primary Care 373 384 .
Anne Eckert, Amandine Grimm & Walter E. Müller. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 16 .
Anne Eckert, Amandine Grimm & Walter E. Müller. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 2649 2664 .
David M. Taylor, Thomas R. E. Barnes & Allan H. Young. 2021. The Maudsley Prescribing Guidelines in Psychiatry. The Maudsley Prescribing Guidelines in Psychiatry 601 677 .
Charlotte Kloft & Robert Hoerr. (2021) EGb 761® Does Not Affect Blood Coagulation and Bleeding Time in Patients with Probable Alzheimer’s Dementia—Secondary Analysis of a Randomized, Double-Blind Placebo-Controlled Trial. Healthcare 9:12, pages 1678.
Crossref
Jia Ke, Qinfang Tian, Qixia Xu, Zhenqin Fu & Qiang Fu. (2021) Mitochondrial dysfunction: A potential target for Alzheimer’s disease intervention and treatment. Drug Discovery Today 26:8, pages 1991-2002.
Crossref
Carlo Tomino, Sara Ilari, Vincenzo Solfrizzi, Valentina Malafoglia, Guglielmo Zilio, Patrizia Russo, Stefania Proietti, Federica Marcolongo, Giovanni Scapagnini, Carolina Muscoli & Paolo Maria Rossini. (2021) Mild Cognitive Impairment and Mild Dementia: The Role of Ginkgo biloba (EGb 761®). Pharmaceuticals 14:4, pages 305.
Crossref
Nagaendran Kandiah, Yee Fai Chan, Christopher Chen, Darwin Dasig, Jacqueline Dominguez, Seol‐Heui Han, Jianping Jia, SangYun Kim, Panita Limpawattana, Li‐Ling Ng, Dinh Toan Nguyen, Paulus Anam Ong, Encarnita Raya‐Ampil, Nor'izzati Saedon, Vorapun Senanarong, Siti Setiati, Harjot Singh, Chuthamanee Suthisisang, Tong Mai Trang, Yuda Turana, Narayanaswamy Venketasubramanian, Fee Mann Yong, Yong Chul Youn & Ralf Ihl. (2020) Strategies for the use of Ginkgo biloba extract, EGb 761 ® , in the treatment and management of mild cognitive impairment in Asia: Expert consensus . CNS Neuroscience & Therapeutics 27:2, pages 149-162.
Crossref
Teresa Delerue, M. Fátima Barroso, Mónica Dias-Teixeira, Maria Figueiredo-González, Cristina Delerue-Matos & Clara Grosso. (2021) Interactions between Ginkgo biloba L. and Scutellaria baicalensis Georgi in multicomponent mixtures towards cholinesterase inhibition and ROS scavenging. Food Research International 140, pages 109857.
Crossref
Samuel Ayodele Egieyeh & Elizabeth Oyebola Egieyeh. 2021. Herbal Medicine in Andrology. Herbal Medicine in Andrology 227 235 .
Ying Guo, Caiyun Gao, Mengke Wang, Fang-fang Fu, Yousry A. El-Kassaby, Tongli Wang & Guibin Wang. (2020) Metabolome and transcriptome analyses reveal flavonoids biosynthesis differences in Ginkgo biloba associated with environmental conditions. Industrial Crops and Products 158, pages 112963.
Crossref
Yana Feodorova, Teodora Tomova, Danail Minchev, Valentin Turiyski, Marian Draganov & Mariana Argirova. (2020) Cytotoxic effect of Ginkgo biloba kernel extract on HCT116 and A2058 cancer cell lines. Heliyon 6:9, pages e04941.
Crossref
Li Yan, Xiang He, Yufan Jin, Jiawei Wang, Fengying Liang, Rongrong Pei, Peibo Li, Yonggang Wang & Weiwei Su. (2020) Modulation of the Aβ-Peptide-Aggregation Pathway by Active Compounds From Platycladus orientalis Seed Extract in Alzheimer’s Disease Models. Frontiers in Aging Neuroscience 12.
Crossref
Xiaoxue Li, Liuyi Lu, Jie Chen, Chao Zhang, Hong Chen & Hui Huang. (2020) New Insight into the Mechanisms of Ginkgo Biloba Extract in Vascular Aging Prevention . Current Vascular Pharmacology 18:4, pages 334-345.
Crossref
Miyuan Wang, Hongye Peng, Zexu Peng, Kailin Huang, Tingting Li, Lei Li, Xin Wu & Heyuan Shi. (2020) Efficacy and safety of ginkgo preparation in patients with vascular dementia. Medicine 99:37, pages e22209.
Crossref
Alan Remde & Raymond Teets. 2020. Geriatric Practice. Geriatric Practice 185 199 .
Md. Jakaria, Md. Ezazul Haque, Duk-Yeon Cho, Shofiul Azam, In-Su Kim & Dong-Kug Choi. (2019) Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death. Molecular Neurobiology 56:8, pages 5799-5814.
Crossref
Imane Lejri, Anastasia Agapouda, Amandine Grimm & Anne Eckert. (2019) Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence. Oxidative Medicine and Cellular Longevity 2019, pages 1-26.
Crossref
Onnita Thancharoen, Chulaporn Limwattananon, Onanong Waleekhachonloet, Thananan Rattanachotphanit, Phumtham Limwattananon & Panita Limpawattana. (2019) Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer’s Disease: A Network Meta-Analysis. Drugs & Aging 36:5, pages 435-452.
Crossref
Nagaendran Kandiah, Paulus Anam Ong, Turana Yuda, Li‐Ling Ng, Kaysar Mamun, Reshma Aziz Merchant, Christopher Chen, Jacqueline Dominguez, Simeon Marasigan, Encarnita Ampil, Van Thong Nguyen, Suraya Yusoff, Yee Fai Chan, Fee Mann Yong, Orapitchaya Krairit, Chuthamanee Suthisisang, Vorapun Senanarong, Yong Ji, Ramesh Thukral & Ralf Ihl. (2019) Treatment of dementia and mild cognitive impairment with or without cerebrovascular disease: Expert consensus on the use of Ginkgo biloba extract, EGb 761 ® . CNS Neuroscience & Therapeutics 25:2, pages 288-298.
Crossref
Agata Walkowiak, Łukasz Ledziński, Mariusz Zapadka & Bogumiła Kupcewicz. (2019) Detection of adulterants in dietary supplements with Ginkgo biloba extract by attenuated total reflectance Fourier transform infrared spectroscopy and multivariate methods PLS-DA and PCA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 208, pages 222-228.
Crossref
William James Deardorff & George T. Grossberg. 2019. Psychopharmacology of Neurologic Disease. Psychopharmacology of Neurologic Disease 5 32 .
Armin von Gunten, Eduardo Nogueira, Henk Parmentier & Irênio Gomes. 2019. Primary Care Mental Health in Older People. Primary Care Mental Health in Older People 251 298 .
Zhiming Shu, Akhtar Hussain Sh, Mohamed Shahen, He Wang, Mahmoud Alagawany, Mohamed E. Abd El-Hac, Shahmir Ali Kalhor, Muhammad Rashid & Piar Ali Shar. (2018) Pharmacological Uses of Ginkgo biloba Extracts for Cardiovascular Disease and Coronary Heart Diseases. International Journal of Pharmacology 15:1, pages 1-9.
Crossref
Stefano Bonassi, Giulia Prinzi, Palma Lamonaca, Patrizia Russo, Irene Paximadas, Giuseppe Rasoni, Raffaella Rossi, Marzia Ruggi, Salvatore Malandrino, Maria Sánchez-Flores, Vanessa Valdiglesias, Barbara Benassi, Francesca Pacchierotti, Paola Villani, Martina Panatta & Eugenia Cordelli. (2018) Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]. BMC Complementary and Alternative Medicine 18:1.
Crossref
Jun Cao, Luyao Chen, Mohan Li, Fuliang Cao, Linguo Zhao & Erzheng Su. (2018) Efficient extraction of proanthocyanidin from Ginkgo biloba leaves employing rationally designed deep eutectic solvent-water mixture and evaluation of the antioxidant activity. Journal of Pharmaceutical and Biomedical Analysis 158, pages 317-326.
Crossref
Roman Jirák. (2018) Ginkgo biloba EGb761 extract and its use in psychiatry. Neurologie pro praxi 19:Demence - strašák 21. století, pages 15-18.
Crossref
Carola Stockburger, Schamim Eckert, Gunter P. Eckert, Kristina Friedland & Walter E. Müller. (2018) Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer’s Disease. Journal of Alzheimer's Disease 64:s1, pages S455-S467.
Crossref
Araceli Garrido Barral, Araceli Garrido Barral, M.ª del Canto de Hoyos Alonso & Ana Tentor Viñas. (2018) Protocolo de diagnóstico y tratamiento del deterioro cognitivo. FMC - Formación Médica Continuada en Atención Primaria 25, pages 1-44.
Crossref
Egemen Savaskan, Heiko Mueller, Robert Hoerr, Armin von Gunten & Serge Gauthier. (2017) Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials . International Psychogeriatrics 30:3, pages 285-293.
Crossref
Olivier Pierre Tible, Florian Riese, Egemen Savaskan & Armin von Gunten. (2017) Best practice in the management of behavioural and psychological symptoms of dementia. Therapeutic Advances in Neurological Disorders 10:8, pages 297-309.
Crossref
John T O’Brien, Clive Holmes, Matthew Jones, Roy Jones, Gill Livingston, Ian McKeith, Peter Mittler, Peter Passmore, Craig Ritchie, Louise Robinson, Elizabeth L Sampson, John-Paul Taylor, Alan Thomas & Alistair Burns. (2017) Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology. Journal of Psychopharmacology 31:2, pages 147-168.
Crossref
N. V. Boiko. (2017) Tinnitus: algorithm of diagnostics and clinical management. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 117:9, pages 88.
Crossref
Jie Dong, Song Li, Jing‐Lin Mo, Huai‐Bin Cai & Wei‐Dong Le. (2016) Nurr1‐Based Therapies for Parkinson's Disease. CNS Neuroscience & Therapeutics 22:5, pages 351-359.
Crossref
Shumita Roy, Ralph H. B. Benedict, Allison S. Drake & Bianca Weinstock-Guttman. (2016) Impact of Pharmacotherapy on Cognitive Dysfunction in Patients with Multiple Sclerosis. CNS Drugs 30:3, pages 209-225.
Crossref