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Acta Orthopaedica Volume 83, 2012 - Issue 1

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Research Article

Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats

Yoshihiro NozakiDepartment of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences

Kenji KumagaiDepartment of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical SciencesCorrespondence[email protected]

Noriaki MiyataDepartment of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences

Masami NiwaDepartment of Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Pages 87-92 | Received 29 Oct 2010, Accepted 26 Sep 2011, Published online: 08 Feb 2012

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https://doi.org/10.3109/17453674.2011.641103

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Ao Wang, Ming Ren & Jincheng Wang. (2018) The pathogenesis of steroid-induced osteonecrosis of the femoral head: A systematic review of the literature. Gene 671, pages 103-109.
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Yuan-Hui Li, Fu-Qiang Gao, Li-Ming Cheng, Mian-Dong Zeng, Qin-Ye Qiu & Ming Ding. (2018) Different changes of microarchitectures of cortical and cancellous bones in sheep femoral head after long-term glucocorticoid interventions. Scientific Reports 8:1.
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Jianzhong Xu, Hanpu Gong, Shitao Lu, Matthey J. Deasey & Quanjun Cui. (2018) Animal models of steroid-induced osteonecrosis of the femoral head—a comprehensive research review up to 2018. International Orthopaedics 42:7, pages 1729-1737.
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Ji-Hua Wei, Qun-Qiang Luo, Yu-Jin Tang, Ji-Xia Chen, Chun-Lan Huang, Ding-Gui Lu & Qian-Li Tang. (2018) Upregulation of microRNA-320 decreases the risk of developing steroid-induced avascular necrosis of femoral head by inhibiting CYP1A2 both in vivo and in vitro. Gene 660, pages 136-144.
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Yini Jiang, Yanqiong Zhang, Haojun Zhang, Bin Zhu, Ping Li, Chao Lu, Ying Xu, Weiheng Chen & Na Lin. (2014) Pravastatin prevents steroid-induced osteonecrosis in rats by suppressing PPARγ expression and activating Wnt signaling pathway. Experimental Biology and Medicine 239:3, pages 347-355.
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Alberto Carli, Anthony Albers, Chantal Séguin & Edward J. Harvey. (2014) The Medical and Surgical Treatment of ARCO Stage-I and II Osteonecrosis of the Femoral Head. JBJS Reviews 2:2.
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G.-Y. Li, Y. Feng, T. S. Cheng, J.-M. Yin & C.-Q. Zhang. (2012) Edaravone, a novel free radical scavenger, prevents steroid-induced osteonecrosis in rabbits. Rheumatology 52:3, pages 438-447.
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Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats

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Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats

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