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Original Articles

PTH 1-34 (teriparatide) may not improve healing in proximal humerus fractures

A randomized, controlled study of 40 patients

Pages 79-82 | Received 14 Jan 2015, Accepted 20 Jun 2015, Published online: 15 Jul 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Håkan Ledin, Lars Good, Torsten Johansson & Per Aspenberg. (2017) No effect of teriparatide on migration in total knee replacement. Acta Orthopaedica 88:3, pages 259-262.
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Letizia Vannucci & Maria Luisa Brandi. (2016) Healing of the bone with anti-fracture drugs. Expert Opinion on Pharmacotherapy 17:17, pages 2267-2272.
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Articles from other publishers (41)

Gigi PG, Ankita Chugh, Kirti Chaudhry, Amanjot Kaur, Pravin Kumar, Shubham Gaur, Shailendra Kumar & Surjit Singh. (2022) Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-label Control Trial. Craniomaxillofacial Trauma & Reconstruction 16:1, pages 23-33.
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Alexandre Hardy, Gabrielle Beetz, Karl Chemali, Margaux Courgeon, Emilie Sandman, David Williamson, Patrick Goetti, Stéphane Leduc, Louis De Beaumont & Dominique M. Rouleau. (2022) Traumatic brain injuries are ignored or discriminated in prospective clinical trials on shoulder fractures: a systematic review. International Orthopaedics 47:1, pages 17-50.
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J.W. Nieves, F. Cosman, D. McMahon, M. Redko, I. Hentschel, R. Bartolotta, M. Loftus, J.J. Kazam, J. Rotman & J. Lane. (2021) Teriparatide and pelvic fracture healing: a phase 2 randomized controlled trial. Osteoporosis International 33:1, pages 239-250.
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Alexander T. Carswell, Katharine G. Eastman, Anna Casey, Matthew Hammond, Lee Shepstone, Estelle Payerne, Andoni P. Toms, James W. MacKay, Ann Marie Swart, Julie P. Greeves & William D. Fraser. (2021) Teriparatide and stress fracture healing in young adults (RETURN – Research on Efficacy of Teriparatide Use in the Return of recruits to Normal duty): study protocol for a randomised controlled trial. Trials 22:1.
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E.A. Gorter, C.R. Reinders, P. Krijnen, N.M. Appelman-Dijkstra & I.B. Schipper. (2021) The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies. Bone Reports 15, pages 101117.
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Liza Osagie-Clouard, Richard Meeson, Anita Sanghani-Kerai, Mathias Bostrom, Timothy Briggs & Gorden Blunn. (2021) The role of intermittent PTH administration in conjunction with allogenic stem cell treatment to stimulate fracture healing. Bone & Joint Research 10:10, pages 659-667.
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Ben Barkham, Hiba Khan & Alex Trompeter. (2021) The use of biological augments in fracture healing: where is the evidence?. Orthopaedics and Trauma 35:5, pages 282-288.
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K. Eastman, M. Gerlach, I. Piec, J. Greeves & W. Fraser. (2021) Effectiveness of parathyroid hormone (PTH) analogues on fracture healing: a meta-analysis. Osteoporosis International 32:8, pages 1531-1546.
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Samuel Shepard, Jake Checketts, Colin Eash, Jennifer Austin, Wade Arthur, Cole Wayant, Mark Johnson, Brent Norris & Matt Vassar. (2021) Evaluation of spin in the abstracts of orthopedic trauma literature: A cross-sectional review. Injury 52:7, pages 1709-1714.
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Arnab Sain, Hemant Bansal, Kirubakaran Pattabiraman & Vijay Sharma. (2021) Present and future scope of recombinant parathyroid hormone therapy in orthopaedics. Journal of Clinical Orthopaedics and Trauma 17, pages 54-58.
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Leopold Henssler, Maximilian Kerschbaum, Moldakulov Z. Mukashevich, Markus Rupp & Volker Alt. (2021) Molecular enhancement of fracture healing - Is there a role for Bone Morphogenetic Protein-2, parathyroid hormone, statins, or sclerostin-antibodies?. Injury 52, pages S49-S57.
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Lei Wang, Linjuan Liu, Sixin Sun, Li Xiao, Qinyi Jiang & Hua Ding. (2021) Effects of Parathyroid Hormone on Osteoporotic Fracture Healing in Mice via Non-Phospholipases C-Dependent Protein Kinase C Signaling Pathway. Journal of Biomaterials and Tissue Engineering 11:5, pages 903-911.
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Junxiong Zhu, Chenggui Zhang, Jialin Jia, Wanqiong Yuan, Min Zhang, Huijie Leng & Chunli Song. (2021) Effect of weekly teriparatide injections on osteoporotic fracture healing: protocol for a double-blind, randomised controlled trial. BMJ Open 11:4, pages e043137.
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Se‐Min Kim, Tony Yuen, Jameel Iqbal, Mishaela R. Rubin & Mone Zaidi. (2020) The NO–cGMP–PKG pathway in skeletal remodeling. Annals of the New York Academy of Sciences 1487:1, pages 21-30.
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Yi-Shan Yang, Yi-Syue Tsou, Wen-Cheng Lo, Yung-Hsiao Chiang & Jiann-Her Lin. (2020) Teriparatide Associated with Fewer Refractures and Higher Body Heights of Cemented Vertebrae after Vertebroplasty: A Matched Cohort Study. Scientific Reports 10:1.
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Meir T. Marmor, Hannah Dailey, Ralph Marcucio & Anthony C. Hunt. (2020) Biomedical research models in the science of fracture healing - Pitfalls & promises. Injury 51:10, pages 2118-2128.
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Jeffery J. Nielsen & Stewart A. Low. (2020) Bone-Targeting Systems to Systemically Deliver Therapeutics to Bone Fractures for Accelerated Healing. Current Osteoporosis Reports 18:5, pages 449-459.
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Esha M. Kapania, Taylor J. Reif, Aaron Tsumura, Jonathan M. Eby & John J. Callaci. (2020) Alcohol‐induced Wnt signaling inhibition during bone fracture healing is normalized by intermittent parathyroid hormone treatment. Animal Models and Experimental Medicine 3:2, pages 200-207.
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Norbert Suhm, Alexander Egger, Christoph Zech, Henrik Eckhardt, Mario Morgenstern & Simon Gratza. (2019) Low acceptance of osteoanabolic therapy with parathyroid hormone in patients with fragility fracture of the pelvis in routine clinical practice: a retrospective observational cohort study. Archives of Orthopaedic and Trauma Surgery 140:3, pages 321-329.
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Nam Hoon Moon, Jae Hoon JangWon Chul ShinSeok Jin Jung. (2020) Effects of Teriparatide on Treatment Outcomes in Osteoporotic Hip and Pelvic Bone Fractures: Meta-analysis and Systematic Review of Randomized Controlled Trials. Hip & Pelvis 32:4, pages 182.
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Elliott N. Schwartz & Clinten P. Edmondson. 2020. Baxter's the Foot and Ankle in Sport. Baxter's the Foot and Ankle in Sport 30 94 .
Junro Yamashita. (2019) The therapeutic potential of parathyroid hormone in dental and oral medicine. Oral Science International 17:1, pages 3-14.
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Junro Yamashita & Laurie K McCauley. (2019) Effects of Intermittent Administration of Parathyroid Hormone and Parathyroid Hormone‐Related Protein on Fracture Healing: A Narrative Review of Animal and Human Studies. JBMR Plus 3:12.
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Kazuma Kitaguchi, Masafumi Kashii, Kosuke Ebina, Satoru Sasaki, Yasunori Tsukamoto, Hideki Yoshikawa & Tsuyoshi Murase. (2019) Effects of Weekly Teriparatide Administration for Vertebral Stability and Bony Union in Patients with Acute Osteoporotic Vertebral Fractures. Asian Spine Journal 13:5, pages 763-771.
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Shasta Henderson, Izuchukwu Ibe, Sean Cahill, Yeon-Ho Chung & Francis Y. Lee. (2019) Bone Quality and Fracture-Healing in Type-1 and Type-2 Diabetes Mellitus. Journal of Bone and Joint Surgery 101:15, pages 1399-1410.
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Frithjof Wagner, Werner Vach, Peter Augat, Patrick A. Varady, Stephanie Panzer, Silke Keiser & Henrik Eckardt. (2019) Daily subcutaneous Teriparatide injection increased bone mineral density of newly formed bone after tibia distraction osteogenesis, a randomized study. Injury 50:8, pages 1478-1482.
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Seung-Ju Kim, Hyun-Soo Park, Dong-Woo Lee & Jae-Won Lee. (2019) Short-term daily teriparatide improve postoperative functional outcome and fracture healing in unstable intertrochanteric fractures. Injury 50:7, pages 1364-1370.
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Andrew C. Clark & Devang Butani. (2019) Percutaneous Sacroplasty for Sacral Insufficiency Fractures: Case Series and Review of Presentation, Diagnosis, and Treatment. American Journal of Interventional Radiology 3, pages 4.
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Hao Hong, Ting Song, Yang Liu, Jun Li, Qilong Jiang, Qizhi Song & Zhongliang Deng. (2019) The effectiveness and safety of parathyroid hormone in fracture healing: A meta-analysis. Clinics 74, pages e800.
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T. J. Blokhuis, P. Patka & W. L. M. Kramer. 2019. Kindertraumachirurgie. Kindertraumachirurgie 671 678 .
Seung-Ju Kim, Hyun-Soo Park, Dong-Woo Lee & Jae-Won Lee. (2018) Does short-term weekly teriparatide improve healing in unstable intertrochanteric fractures?. Journal of Orthopaedic Surgery 26:3, pages 230949901880248.
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Andrea V Haas & Meryl S LeBoff. (2018) Osteoanabolic Agents for Osteoporosis. Journal of the Endocrine Society 2:8, pages 922-932.
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Paul Kostenuik & Faisal M. Mirza. (2017) Fracture healing physiology and the quest for therapies for delayed healing and nonunion. Journal of Orthopaedic Research 35:2, pages 213-223.
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Dong-Hyun LeeJi Wan Kim. (2017) Bone Substitutes and the Advancement for Enhancing Bone Healing. Journal of the Korean Fracture Society 30:2, pages 102.
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Sang-Min KimKyung-Chung KangJi Wan KimSeung-Jae LimMyung Hoon Hahn. (2017) Current Role and Application of Teriparatide in Fracture Healing of Osteoporotic Patients: A Systematic Review. Journal of Bone Metabolism 24:1, pages 65.
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S.M. Ott. 2017. Materials for Bone Disorders. Materials for Bone Disorders 29 82 .
Zhongju Shi, Hengxing Zhou, Bin Pan, Lu Lu, Jun Liu, Yi Kang, Xue Yao & Shiqing Feng. (2016) Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis. PLOS ONE 11:12, pages e0168691.
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Per Aspenberg, Jorge Malouf, Umberto Tarantino, Pedro A. García-Hernández, Costantino Corradini, Søren Overgaard, Jan J. Stepan, Lars Borris, Eric Lespessailles, Frede Frihagen, Kyriakos Papavasiliou, Helmut Petto, José Ramón Caeiro & Fernando Marin. (2016) Effects of Teriparatide Compared with Risedronate on Recovery After Pertrochanteric Hip Fracture. Journal of Bone and Joint Surgery 98:22, pages 1868-1878.
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C. Bartl, D. Stengel, J. Gülke & F. Gebhard. (2016) Klinische Ergebnisse nach konservativer und operativer Therapie der distalen Radiusfraktur beim älteren PatientenClinical results following conservative and surgical treatment of osteoporotic distal radius fractures in the elderly. Der Unfallchirurg 119:9, pages 723-731.
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Shenghan Lou, Houchen Lv, Guoqi Wang, Licheng Zhang, Ming Li, Zhirui Li, Lihai Zhang & Peifu Tang. (2016) The Effect of Teriparatide on Fracture Healing of Osteoporotic Patients: A Meta-Analysis of Randomized Controlled Trials. BioMed Research International 2016, pages 1-10.
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