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Research Article

A pilot trial of memantine and riluzole in ALS: Correlation to CSF biomarkers

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Pages 514-519 | Received 02 Feb 2010, Accepted 01 Aug 2010, Published online: 14 Sep 2010

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JingSi Jiang, Yan Wang & Min Deng. (2022) New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022. Frontiers in Pharmacology 13.
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Marie Dreger, Robert Steinbach, Markus Otto, Martin R Turner & Julian Grosskreutz. (2022) Cerebrospinal fluid biomarkers of disease activity and progression in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 93:4, pages 422-435.
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Débora Lanznaster, Rudolf C. Hergesheimer, Salah Eddine Bakkouche, Stephane Beltran, Patrick Vourc’h, Christian R. Andres, Diane Dufour-Rainfray, Philippe Corcia & Hélène Blasco. (2020) Aβ1-42 and Tau as Potential Biomarkers for Diagnosis and Prognosis of Amyotrophic Lateral Sclerosis. International Journal of Molecular Sciences 21:8, pages 2911.
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Rangariroyashe Hannah Chipika, Eoin Finegan, Stacey Li Hi Shing, Orla Hardiman & Peter Bede. (2019) Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS. Frontiers in Neurology 10.
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Loqman A. Mohamed, Shashirekha Markandaiah, Silvia Bonanno, Piera Pasinelli & Davide Trotti. (2017) Blood–Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies. The AAPS Journal 19:6, pages 1600-1614.
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Lucas T. Vu & Robert Bowser. (2016) Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis. Neurotherapeutics 14:1, pages 119-134.
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Michael Benatar, Kevin Boylan, Andreas Jeromin, Seward B. Rutkove, James Berry, Nazem Atassi & Lucie Bruijn. (2016) ALS biomarkers for therapy development: State of the field and future directions. Muscle & Nerve 53:2, pages 169-182.
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Nadine Bakkar, Ashley Boehringer & Robert Bowser. (2015) Use of biomarkers in ALS drug development and clinical trials. Brain Research 1607, pages 94-107.
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Brian A. Wall, Janet Wangari-Talbot, Seung S. Shin, Devora Schiff, Jairo Sierra, Lumeng J. Yu, Atif Khan, Bruce Haffty, James S. Goydos & Suzie Chen. (2014) Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells. Pigment Cell & Melanoma Research 27:2, pages 263-274.
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Alida Spalloni, Michele Nutini & Patrizia Longone. (2013) Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:2, pages 312-322.
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Matthew Gladman, Merit Cudkowicz & Lorne Zinman. (2012) Enhancing clinical trials in neurodegenerative disorders. Current Opinion in Neurology 25:6, pages 735-742.
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Todd D. Levine, Robert Bowser, Nicole C. Hank, Stephen Gately, Dietrich Stephan, David S. Saperstein & Kendall Van Keuren-Jensen. (2012) A Pilot Trial of Pioglitazone HCl and Tretinoin in ALS: Cerebrospinal Fluid Biomarkers to Monitor Drug Efficacy and Predict Rate of Disease Progression. Neurology Research International 2012, pages 1-6.
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Paul H. Gordon & Vincent Meininger. (2011) How can we improve clinical trials in amyotrophic lateral sclerosis?. Nature Reviews Neurology 7:11, pages 650-654.
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