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Research Article

Uncovering amyotrophic lateral sclerosis phenotypes: Clinical features and long-term follow-up of upper motor neuron-dominant ALS

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Pages 278-282 | Received 01 Feb 2011, Accepted 09 Apr 2011, Published online: 27 Jun 2011

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Christian Marques Couto, Elisa de Melo Queiroz, Renata Nogueira, Ana Paula Pires Duarte Küsel & Osvaldo J. M. Nascimento. (2022) A Brazilian multicentre study on the clinical and epidemiological profiles of 1116 patients with amyotrophic lateral sclerosis and its phenotypic variants. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23:5-6, pages 353-362.
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Matthew S. Devine, Emma Ballard, Peter O’Rourke, Matthew C. Kiernan, Pamela A. Mccombe & Robert D. Henderson. (2016) Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 17:3-4, pages 184-190.
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Jing Ma, Xiaomin Pang, Shan Huang, Jing Zhang, Juan Wang, Rongjuan Zhao, Xueli Chang, Junhong Guo & Wei Zhang. (2021) Genetic analysis in Chinese patients with familial or young-onset amyotrophic lateral sclerosis. Neurological Sciences 43:4, pages 2579-2587.
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Graziella Donatelli, Mauro Costagli, Paolo Cecchi, Gianmichele Migaleddu, Francesca Bianchi, Paolo Frumento, Gabriele Siciliano & Mirco Cosottini. (2022) Motor cortical patterns of upper motor neuron pathology in amyotrophic lateral sclerosis: A 3 T MRI study with iron-sensitive sequences. NeuroImage: Clinical 35, pages 103138.
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Justin R Abbatemarco, Austin Griffin, Noble G Jones, Jennifer Hartman, Keith McKee, Zhini Wang, Sean J Nagel, Andre G Machado & Francois Bethoux. (2020) Long-term outcomes of intrathecal baclofen in ambulatory multiple sclerosis patients: A single-center experience. Multiple Sclerosis Journal 27:6, pages 933-941.
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Serena Lattante & Mario Sabatelli. 2021. Spectrums of Amyotrophic Lateral Sclerosis. Spectrums of Amyotrophic Lateral Sclerosis 1 16 .
Lu Chen, Yong Chen, Mingming Zhao, Lemin Zheng & Dongsheng Fan. (2020) Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis. Scientific Reports 10:1.
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Laura Libonati, Tommaso Francesco Barone, Marco Ceccanti, Chiara Cambieri, Giorgio Tartaglia, Emanuela Onesti, Antonio Petrucci, Vittorio Frasca & Maurizio Inghilleri. (2019) Heteronymous H reflex in temporal muscle as sign of hyperexcitability in ALS patients. Clinical Neurophysiology 130:8, pages 1455-1459.
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Hongxia Lei, Elisabeth Dirren, Carole Poitry-Yamate, Bernard L Schneider, Rolf Gruetter & Patrick Aebischer. (2018) Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. Journal of Cerebral Blood Flow & Metabolism 39:7, pages 1283-1298.
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W.B.V.R. Pinto, R. Debona, P.P. Nunes, A.C.D. Assis, C.G. Lopes, T. Bortholin, R.B. Dias, F.G.M. Naylor, M.A.T. Chieia, P.V.S. Souza & A.S.B. Oliveira. (2019) Atypical Motor Neuron Disease variants: Still a diagnostic challenge in Neurology. Revue Neurologique 175:4, pages 221-232.
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William Huynh, Thanuja Dharmadasa, Steve Vucic & Matthew C. Kiernan. (2019) Functional Biomarkers for Amyotrophic Lateral Sclerosis. Frontiers in Neurology 9.
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Qian-Qian Wei, Yongping Chen, Xueping Chen, Bei Cao, RuWei Ou, Lingyu Zhang, Yanbing Hou & Huifang Shang. (2018) Clinical and prognostic features of ALS/MND in different phenotypes–data from a hospital-based registry. Brain Research Bulletin 142, pages 403-408.
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Katharine Nicholson, Alyssa Murphy, Erin McDonnell, Jordan Shapiro, Ericka Simpson, Jonathan Glass, Hiroshi Mitsumoto, Dallas Forshew, Robert Miller & Nazem Atassi. (2017) Improving symptom management for people with amyotrophic lateral sclerosis. Muscle & Nerve 57:1, pages 20-24.
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C. Tard, L. Defebvre, C. Moreau, D. Devos & V. Danel-Brunaud. (2017) Clinical features of amyotrophic lateral sclerosis and their prognostic value. Revue Neurologique 173:5, pages 263-272.
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Andrea Calvo, Cristina Moglia, Christian Lunetta, Kalliopi Marinou, Nicola Ticozzi, Gianluca Drago Ferrante, Carlo Scialo, Gianni Sorarù, Francesca Trojsi, Amelia Conte, Yuri M. Falzone, Rosanna Tortelli, Massimo Russo, Adriano Chiò, Valeria Ada Sansone, Gabriele Mora, Vincenzo Silani, Paolo Volanti, Claudia Caponnetto, Giorgia Querin, Maria Rosaria Monsurrò, Mario Sabatelli, Nilo Riva, Giancarlo Logroscino, Sonia Messina, Nicola Fini & Jessica Mandrioli. (2016) Factors predicting survival in ALS: a multicenter Italian study. Journal of Neurology 264:1, pages 54-63.
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William Huynh, Neil G. Simon, Julian Grosskreutz, Martin R. Turner, Steve Vucic & Matthew C. Kiernan. (2016) Assessment of the upper motor neuron in amyotrophic lateral sclerosis. Clinical Neurophysiology 127:7, pages 2643-2660.
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Mario Sabatelli, Giuseppe Marangi, Amelia Conte, Giorgio Tasca, Marcella Zollino & Serena Lattante. (2016) New ALS-Related Genes Expand the Spectrum Paradigm of Amyotrophic Lateral Sclerosis . Brain Pathology 26:2, pages 266-275.
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Huub Creemers, Hepke Grupstra, Frans Nollet, Leonard H. van den Berg & Anita Beelen. (2014) Prognostic factors for the course of functional status of patients with ALS: a systematic review. Journal of Neurology 262:6, pages 1407-1423.
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Jeffrey Rosenfeld & Michael J. Strong. (2015) Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease. Neurotherapeutics 12:2, pages 317-325.
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Neil G. Simon, Martin R. Turner, Steve Vucic, Ammar Al‐Chalabi, Jeremy Shefner, Catherine Lomen‐Hoerth & Matthew C. Kiernan. (2014) Quantifying disease progression in amyotrophic lateral sclerosis. Annals of Neurology 76:5, pages 643-657.
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Francois Bethoux, Nicholas Boulis, Shearwood McClellandIIIIII, Mary Alissa Willis, Mariam Hussain, Andre Machado, Lydia Mychkovsky, Darlene Stough, Matt Sutliff & Erik P. Pioro. (2013) Use of Intrathecal Baclofen for Treatment of Severe Spasticity in Selected Patients With Motor Neuron Disease. Neurorehabilitation and Neural Repair 27:9, pages 828-833.
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M Sabatelli, A Conte & M Zollino. (2013) Clinical and genetic heterogeneity of amyotrophic lateral sclerosis. Clinical Genetics 83:5, pages 408-416.
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Martin R Turner, Orla Hardiman, Michael Benatar, Benjamin R Brooks, Adriano Chio, Mamede de Carvalho, Paul G Ince, Cindy Lin, Robert G Miller, Hiroshi Mitsumoto, Garth Nicholson, John Ravits, Pamela J Shaw, Michael Swash, Kevin Talbot, Bryan J Traynor, Leonard H Van den Berg, Jan H Veldink, Steve Vucic & Matthew C Kiernan. (2013) Controversies and priorities in amyotrophic lateral sclerosis. The Lancet Neurology 12:3, pages 310-322.
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Marco Luigetti, Amelia Conte, Alessandra Del Grande, Giulia Bisogni, Angela Romano & Mario Sabatelli. (2011) Sural nerve pathology in ALS patients: a single-centre experience. Neurological Sciences 33:5, pages 1095-1099.
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Serena LattanteAmelia ConteMarcella ZollinoMarco LuigettiAlessandra Del GrandeGiuseppe MarangiAngela RomanoAlessandro MarcaccioEmiliana MeleoGiulia BisogniPaolo Maria RossiniMario Sabatelli. (2012) Contribution of major amyotrophic lateral sclerosis genes to the etiology of sporadic disease. Neurology 79:1, pages 66-72.
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