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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 14, 2013 - Issue 1
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Research Article

Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study: Subgroup analysis of demographic and clinical characteristics

Stacy A. RudnickiDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, ArkansasCorrespondence[email protected]
,
James D. BerryDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts
,
Evan IngersollKnopp Biosciences, Pittsburgh, Pennsylvania, and
,
Don ArchibaldKnopp Biosciences, Pittsburgh, Pennsylvania, and
,
Merit E. CudkowiczDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts
,
Douglas A. KerrBiogen Idec, Cambridge, Massachusetts, USA
&
Yingwen DongBiogen Idec, Cambridge, Massachusetts, USA
 show all
Pages 44-51 | Received 31 May 2012, Accepted 19 Aug 2012, Published online: 17 Sep 2012

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Bello Hamidou, Benoit Marin, Geraldine Lautrette, Marie Nicol, William Camu, Philippe Corcia, Marie-Christine Arnes-Bes, Christine Tranchant, Pierre Clavelou, Didier Hannequin, Giroud Maurice, Katell Beauvais, Jean-Christophe Antoine, Véronique Danel-Brunaud, Fausto Viader, Pierre-Marie Preux & Philippe Couratier. (2017) Exploring the diagnosis delay and ALS functional impairment at diagnosis as relevant criteria for clinical trial enrolment*. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18:7-8, pages 519-527.
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H Blasco, F Patin, CR Andres, P Corcia & PH Gordon. (2016) Amyotrophic Lateral Sclerosis, 2016: existing therapies and the ongoing search for neuroprotection. Expert Opinion on Pharmacotherapy 17:12, pages 1669-1682.
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Elizabeth D. Bacci, Dorota Staniewska, Karin S. Coyne, Stacey Boyer, Leigh Ann White, Neta Zach & Jesse M. Cedarbaum. (2016) Item response theory analysis of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised in the Pooled Resource Open-Access ALS Clinical Trials Database. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 17:3-4, pages 157-167.
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. (2015) ALSUntangled No. 30: Methylcobalamin. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16:7-8, pages 536-539.
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Hazuki Watanabe, Naoki Atsuta, Ryoichi Nakamura, Akihiro Hirakawa, Hirohisa Watanabe, Mizuki Ito, Jo Senda, Masahisa Katsuno, Yuishin Izumi, Mitsuya Morita, Hiroyuki Tomiyama, Akira Taniguchi, Ikuko Aiba, Koji Abe, Kouichi Mizoguchi, Masaya Oda, Osamu Kano, Koichi Okamoto, Satoshi Kuwabara, Kazuko Hasegawa, Takashi Imai, Masashi Aoki, Shoji Tsuji, Imaharu Nakano, Ryuji Kaji & Gen Sobue. (2015) Factors affecting longitudinal functional decline and survival in amyotrophic lateral sclerosis patients. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16:3-4, pages 230-236.
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Ettore Beghi, Elisabetta Pupillo, Virginio Bonito, Paolo Buzzi, Claudia Caponnetto, Adriano Chiò, Massimo Corbo, Fabio Giannini, Maurizio Inghilleri, Vincenzo La Bella, Giancarlo Logroscino, Lorenzo Lorusso, Christian Lunetta, Letizia Mazzini, Paolo Messina, Gabriele Mora, Michele Perini, Maria Lidia Quadrelli, Vincenzo Silani, Isabella L. Simone & Lucio Tremolizzo. (2013) Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14:5-6, pages 397-405.
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James D. Berry, Robert Miller, Dan H. Moore, Merit E. Cudkowicz, Leonard H. Van Den Berg, Douglas A. Kerr, Yingwen Dong, Evan W. Ingersoll & Donald Archibald. (2013) The Combined Assessment of Function and Survival (CAFS): A new endpoint for ALS clinical trials. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14:3, pages 162-168.
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Pedro Soares, Catia Silva, Daniel Chavarria, Filomena S.G. Silva, Paulo J. Oliveira & Fernanda Borges. (2023) Drug discovery and amyotrophic lateral sclerosis: Emerging challenges and therapeutic opportunities. Ageing Research Reviews 83, pages 101790.
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Megan Dubowsky, Stephanie R Shepheard & Mary-Louise Rogers. 2022. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1893 1929 .
Megan Dubowsky, Stephanie R Shepheard & Mary-Louise Rogers. 2021. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1 37 .
Elena Obrador, Rosario Salvador-Palmer, Rafael López-Blanch, Ali Jihad-Jebbar, Soraya L. Vallés & José M. Estrela. (2021) The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS. International Journal of Molecular Sciences 22:12, pages 6352.
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Kristiana Salmon & Angela Genge. 2021. Spectrums of Amyotrophic Lateral Sclerosis. Spectrums of Amyotrophic Lateral Sclerosis 161 180 .
Teresa Cunha-Oliveira, Liliana Montezinho, Catarina Mendes, Omidreza Firuzi, Luciano Saso, Paulo J. Oliveira & Filomena S. G. Silva. (2020) Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention. Oxidative Medicine and Cellular Longevity 2020, pages 1-29.
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Rangariroyashe Hannah Chipika, Eoin Finegan, Stacey Li Hi Shing, Orla Hardiman & Peter Bede. (2019) Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS. Frontiers in Neurology 10.
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G. Grolez, C. Moreau, V. Danel-Brunaud, C. Delmaire, R. Lopes, P. F. Pradat, M. M. El Mendili, L. Defebvre & D. Devos. (2016) The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review. BMC Neurology 16:1.
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Vijay Kumar, Asimul Islam, Md. Imtaiyaz Hassan & Faizan Ahmad. (2016) Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning. European Journal of Medicinal Chemistry 121, pages 903-917.
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Conceicao Moura Mirian, Rita Carvalho Garbi Novaes Maria, SSP Zago Yuri, Junio Eduardo Emanoel & Augusto Casulari Luiz. (2016) Efficacy and effectiveness of drug treatments in amyotrophic lateral sclerosis: A systematic review with meta-analysis. African Journal of Pharmacy and Pharmacology 10:13, pages 257-269.
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A. C. Ludolph. (2016) The TUDCA trial - innovative trial designs for amyotrophic lateral sclerosis drugs?. European Journal of Neurology 23:1, pages 11-12.
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Valentin K. Gribkoff. 2015. The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria. The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria 295 321 .
Ching-Hua LuCorrie Macdonald-WallisElizabeth GrayNeil PearceAxel PetzoldNiklas NorgrenGavin GiovannoniPietro FrattaKatie SidleMark FishRichard OrrellRobin HowardKevin TalbotLinda GreensmithJens KuhleMartin R. TurnerAndrea Malaspina. (2015) Neurofilament light chain. Neurology 84:22, pages 2247-2257.
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Sabrina Paganoni, Merit Cudkowicz & James D Berry. (2014) Outcome measures in amyotrophic lateral sclerosis clinical trials. Clinical Investigation 4:7, pages 605-618.
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Ammar Al-Chalabi. (2014) High-calorie diets in amyotrophic lateral sclerosis. The Lancet 383:9934, pages 2028-2030.
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Xiaowei W. Su, James R. Broach, James R. Connor, Glenn S. Gerhard & Zachary Simmons. (2014) Genetic heterogeneity of amyotrophic lateral sclerosis: Implications for clinical practice and research. Muscle & Nerve 49:6, pages 786-803.
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H Muyderman & T Chen. (2014) Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?. British Journal of Pharmacology 171:8, pages 2191-2205.
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Barış Genç & P. Hande Özdinler. (2014) Moving forward in clinical trials for ALS: motor neurons lead the way please. Drug Discovery Today 19:4, pages 441-449.
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Mary-Louise Rogers. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1755 1785 .

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