1,515
Views
48
CrossRef citations to date
0
Altmetric
ARTICLE

Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained Males

, PhD, &

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Callum S. Harnden, JOSEPH Agu & TOM Gascoyne. (2023) Effects of citrulline on endurance performance in young healthy adults: a systematic review and meta-analysis. Journal of the International Society of Sports Nutrition 20:1.
Read now
Matthew T. Stratton, Madelin R. Siedler, Patrick S. Harty, Christian Rodriguez, Jake R. Boykin, Jacob J. Green, Dale S. Keith, Sarah J. White, Brielle DeHaven, Abegale D. Williams & Grant M. Tinsley. (2022) The influence of caffeinated and non-caffeinated multi-ingredient pre-workout supplements on resistance exercise performance and subjective outcomes. Journal of the International Society of Sports Nutrition 19:1, pages 126-149.
Read now
Laura Meimoun, Émilie Pecchi, Christophe Vilmen, David Bendahan & Benoît Giannesini. (2022) Effect of citrulline malate supplementation on muscle function and bioenergetics during short-term repeated bouts of fatiguing exercise. Journal of Sports Sciences 40:17, pages 1981-1990.
Read now
Eric T. Trexler, Dale S. Keith, Adam A. Lucero, Lee Stoner, Todd A. Schwartz, Adam M. Persky, Eric D. Ryan & Abbie E. Smith-Ryan. (2020) Effects of Citrulline Malate and Beetroot Juice Supplementation on Energy Metabolism and Blood Flow During Submaximal Resistance Exercise. Journal of Dietary Supplements 17:6, pages 698-717.
Read now
Kara Blohm, Joshua Beidler, Phil Rosen, Jochen Kressler & Mee Young Hong. (2020) Effect of acute watermelon juice supplementation on post-submaximal exercise heart rate recovery, blood lactate, blood pressure, blood glucose and muscle soreness in healthy non-athletic men and women. International Journal of Food Sciences and Nutrition 71:4, pages 482-489.
Read now
Andrew J. Chappell, Daniel M. Allwood & Trevor N. Simper. (2020) Citrulline Malate Fails to Improve German Volume Training Performance in Healthy Young Men and Women. Journal of Dietary Supplements 17:3, pages 249-260.
Read now
Jeffrey M. Rogers, Joshua Gills & Michelle Gray. (2020) Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults. Journal of the International Society of Sports Nutrition 17:1.
Read now
Andrew J. Chappell, Daniel M. Allwood, Rebecca Johns, Samantha Brown, Kiran Sultana, Annie Anand & Trevor Simper. (2018) Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females. Journal of the International Society of Sports Nutrition 15:1.
Read now
Chad M. Kerksick, Colin D. Wilborn, Michael D. Roberts, Abbie Smith-Ryan, Susan M. Kleiner, Ralf Jäger, Rick Collins, Mathew Cooke, Jaci N. Davis, Elfego Galvan, Mike Greenwood, Lonnie M. Lowery, Robert Wildman, Jose Antonio & Richard B. Kreider. (2018) ISSN exercise & sports nutrition review update: research & recommendations. Journal of the International Society of Sports Nutrition 15:1.
Read now
Paul Hwang, Flor E. Morales Marroquín, Josh Gann, Tom Andre, Sarah McKinley-Barnard, Caelin Kim, Masahiko Morita & Darryn S. Willoughby. (2018) Eight weeks of resistance training in conjunction with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained males. Journal of the International Society of Sports Nutrition 15:1.
Read now
Ascensión Martínez-Sánchez, Domingo J. Ramos-Campo, Bárbara Fernández-Lobato, Jacobo A. Rubio-Arias, Fernando Alacid & Encarna Aguayo. (2017) Biochemical, physiological, and performance response of a functional watermelon juice enriched in L-citrulline during a half-marathon race. Food & Nutrition Research 61:1.
Read now
Jordan M. Glenn, Michelle Gray, Austen Jensen, Matthew S. Stone & Jennifer L. Vincenzo. (2016) Acute citrulline-malate supplementation improves maximal strength and anaerobic power in female, masters athletes tennis players. European Journal of Sport Science 16:8, pages 1095-1103.
Read now

Articles from other publishers (34)

Jerry Mayo, Brian C. Lyons, W. Steven Tucker & Benjamin Wax. (2023) Acute Citrulline Malate Supplementation Does Not Improve Anaerobic Capacity in Healthy Young Adults: A Pilot Study. Journal of Exercise and Nutrition 6:1.
Crossref
Adam M. Gonzalez, Yang Yang, Gerald T. Mangine, Anthony G. Pinzone, Jamie J. Ghigiarelli & Katie M. Sell. (2023) Acute Effect of L-Citrulline Supplementation on Resistance Exercise Performance and Muscle Oxygenation in Recreationally Resistance Trained Men and Women. Journal of Functional Morphology and Kinesiology 8:3, pages 88.
Crossref
Joshua L. Gills, Blake Spliker, Jordan M. Glenn, David Szymanski, Braden Romer, Ho-Cheng Lu & Michelle Gray. (2023) Acute Citrulline-Malate Supplementation Increases Total Work in Short Lower-Body Isokinetic Tasks for Recreationally Active Females During Menstruation. Journal of Strength and Conditioning Research 37:6, pages 1225-1230.
Crossref
Hun-Young Park, Sung-Woo Kim, Jisoo Seo, Yanghoon P. Jung, Hyunji Kim, Ah-Jin Kim, Sonwoo Kim & Kiwon Lim. (2023) Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review. Nutrients 15:5, pages 1268.
Crossref
Adam M. Gonzalez, Jeremy R. Townsend, Anthony G. Pinzone & Jay R. Hoffman. (2023) Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature. Nutrients 15:3, pages 660.
Crossref
Eduard Bezuglov, Ryland Morgans, Artemii Lazarev, Evgeny Kalinin, Mikhail Butovsky, Evgeny Savin, Eduard Tzgoev, Bekzhan Pirmakhanov, Anton Emanov, Andrey Zholinsky & Oleg Talibov. (2022) The Effect of a Single Dose of Citrulline on the Physical Performance of Soccer-Specific Exercise in Adult Elite Soccer Players (A Pilot Randomized Double-Blind Trial). Nutrients 14:23, pages 5036.
Crossref
Siphamandla Nyawose, Rowena Naidoo, Nenad Naumovski & Andrew J. McKune. (2022) The Effects of Consuming Amino Acids L-Arginine, L-Citrulline (and Their Combination) as a Beverage or Powder, on Athletic and Physical Performance: A Systematic Review. Beverages 8:3, pages 48.
Crossref
Adam M. Gonzalez, Anthony G. Pinzone, Shaina E. Lipes, Gerald T. Mangine, Jeremy R. Townsend, Timothy D. Allerton, Katie M. Sell & Jamie J. Ghigiarelli. (2022) Effect of watermelon supplementation on exercise performance, muscle oxygenation, and vessel diameter in resistance-trained men. European Journal of Applied Physiology 122:7, pages 1627-1638.
Crossref
Manuel I. López-Martínez, Marta Miguel & Marta Garcés-Rimón. (2022) Protein and Sport: Alternative Sources and Strategies for Bioactive and Sustainable Sports Nutrition. Frontiers in Nutrition 9.
Crossref
José Burgos, Aitor Viribay, Julio Calleja-González, Diego Fernández-Lázaro, Jurgi Olasagasti-Ibargoien, Jesús Seco-Calvo & Juan Mielgo-Ayuso. (2022) Long-Term Combined Effects of Citrulline and Nitrate-Rich Beetroot Extract Supplementation on Recovery Status in Trained Male Triathletes: A Randomized, Double-Blind, Placebo-Controlled Trial. Biology 11:1, pages 75.
Crossref
José Burgos, Aitor Viribay, Diego Fernández-Lázaro, Julio Calleja-González, Josefa González-Santos & Juan Mielgo-Ayuso. (2021) Combined Effects of Citrulline Plus Nitrate-Rich Beetroot Extract Co-Supplementation on Maximal and Endurance-Strength and Aerobic Power in Trained Male Triathletes: A Randomized Double-Blind, Placebo-Controlled Trial. Nutrients 14:1, pages 40.
Crossref
Lewis A. Gough, S. Andy Sparks, Lars R. McNaughton, Matthew F. Higgins, Josh W. Newbury, Eric Trexler, Mark A. Faghy & Craig A. Bridge. (2021) A critical review of citrulline malate supplementation and exercise performance. European Journal of Applied Physiology 121:12, pages 3283-3295.
Crossref
Fredrik Tonstad Vårvik, Thomas Bjørnsen & Adam M. Gonzalez. (2021) Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis. International Journal of Sport Nutrition and Exercise Metabolism 31:4, pages 350-358.
Crossref
Alyssa N. Fick, Robert J. Kowalsky, Matthew S. Stone, Christopher M. Hearon & Tyler M. Farney. (2021) Acute and Chronic Citrulline Malate Supplementation on Muscle Contractile Properties and Fatigue Rate of the Quadriceps. International Journal of Sport Nutrition and Exercise Metabolism, pages 1-7.
Crossref
Hye Chang Rhim, Sung Jong Kim, Jewel Park & Ki-Mo Jang. (2020) Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis. Journal of Sport and Health Science 9:6, pages 553-561.
Crossref
Adam M. GonzalezDavid D. ChurchJeremy R. Townsend & Reza Bagheri. (2020) Emerging Nutritional Supplements for Strength and Hypertrophy: An Update of the Current Literature. Strength & Conditioning Journal 42:5, pages 57-70.
Crossref
Adam M. Gonzalez & Eric T. Trexler. (2020) Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Journal of Strength and Conditioning Research 34:5, pages 1480-1495.
Crossref
Jin A. Yang, Kyung Eun Lee, Ji Hyun Park, Jeong Yee, Jae Youn Kim & Hye Sun Gwak. (2019) Effects of Citrulline Supplementation on Body Weight in Patients With Hepatobiliary Pancreatic Surgery. Nutrition in Clinical Practice 35:2, pages 323-330.
Crossref
Eric T. TrexlerDale S. KeithTodd A. Schwartz, Eric D. RyanLee StonerAdam M. Persky & Abbie E. Smith-Ryan. (2019) Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise. Journal of Strength and Conditioning Research 33:9, pages 2321-2329.
Crossref
J. Casonatto, J.V. Cavalari, K.F. Goessler, D.G.D. Christofaro, M.D. Polito, D.M. Enokida & K. Grandolfi. (2019) Citrulline malate supplementation might potentiate post-exercise hypotension in hypertensives: A 24-hour analysis. Science & Sports 34:4, pages 261.e1-261.e9.
Crossref
Juma Iraki, Peter Fitschen, Sergio Espinar & Eric Helms. (2019) Nutrition Recommendations for Bodybuilders in the Off-Season: A Narrative Review. Sports 7:7, pages 154.
Crossref
Mochammad Rizal, Calista Segalita & Trias Mahmudiono. (2019) The Effect of Watermelon Beverage Ingestion on Fatigue Index in Young-Male, Recreational Football Players. Asian Journal of Sports Medicine 10:2.
Crossref
Eric T. Trexler, Adam M. Persky, Eric D. Ryan, Todd A. Schwartz, Lee Stoner & Abbie E. Smith-Ryan. (2019) Acute Effects of Citrulline Supplementation on High-Intensity Strength and Power Performance: A Systematic Review and Meta-Analysis. Sports Medicine 49:5, pages 707-718.
Crossref
Jason Cholewa, Eric Trexler, Fernanda Lima-Soares, Kassiana de Araújo Pessôa, Rayssa Sousa-Silva, Azenildo Moura Santos, Xia Zhi, Humberto Nicastro, Christian Emmanuel Torres Cabido, Marcelo Conrado de Freitas, Fabricio Rossi & Nelo Eidy Zanchi. (2019) Effects of dietary sports supplements on metabolite accumulation, vasodilation and cellular swelling in relation to muscle hypertrophy: A focus on “secondary” physiological determinants. Nutrition 60, pages 241-251.
Crossref
Álvaro Huerta Ojeda, Andreina Domínguez de Hanna & Guillermo Barahona-Fuentes. (2019) The effect of supplementation with L-arginine and L-citrulline on physical performance: a systematic review. Nutrición Hospitalaria.
Crossref
Syafira Kandinasti & Farapti Farapti. (2018) Obesitas: Pentingkah Memperhatikan Konsumsi Makanan di Akhir Pekan?. Amerta Nutrition 2:4, pages 307.
Crossref
Mochammad Rizal & Calista Segalita. (2018) Peran Asam Amino Sitrulin dalam Meningkatkan Performa Olahraga Pada Atlet. Amerta Nutrition 2:4, pages 299.
Crossref
Kamila GRANDOLFI, João Vagner CAVALARI, Renata Cristina GÓES, Marcos Doederlein POLITO & Juliano CASONATTO. (2018) Acute citrulline oral supplementation induces greater post-exercise hypotension response in hypertensive than normotensive individuals. Revista de Nutrição 31:6, pages 509-521.
Crossref
Adam M. Gonzalez, Robert W. Spitz, Jamie J. Ghigiarelli, Katie M. Sell & Gerald T. Mangine. (2018) Acute Effect of Citrulline Malate Supplementation on Upper-Body Resistance Exercise Performance in Recreationally Resistance-Trained Men. Journal of Strength and Conditioning Research 32:11, pages 3088-3094.
Crossref
Arthur Goron & Christophe Moinard. (2018) Amino acids and sport: a true love story?. Amino Acids 50:8, pages 969-980.
Crossref
Fatih Kiyici, Hüseyin Eroğlu, N. Fazil Kishali & Guleda Burmaoglu. (2017) The Effect of Citrulline/Malate on Blood Lactate Levels in Intensive Exercise. Biochemical Genetics 55:5-6, pages 387-394.
Crossref
Douglas da Silva, Jeferson Jacinto, Walquiria de Andrade, Mirela Roveratti, José Estoche, Mario Balvedi, Douglas de Oliveira, Rubens da Silva & Andreo Aguiar. (2017) Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men. Nutrients 9:10, pages 1132.
Crossref
Ascensión Martínez-Sánchez, Fernando Alacid, Jacobo A. Rubio-Arias, Bárbara Fernández-Lobato, Domingo J. Ramos-Campo & Encarna Aguayo. (2017) Consumption of Watermelon Juice Enriched in l -Citrulline and Pomegranate Ellagitannins Enhanced Metabolism during Physical Exercise . Journal of Agricultural and Food Chemistry 65:22, pages 4395-4404.
Crossref
Jordan M. Glenn, Michelle Gray, Lauren N. Wethington, Matthew S. Stone, Rodger W. StewartJr.Jr. & Nicole E. Moyen. (2015) Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained females. European Journal of Nutrition 56:2, pages 775-784.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.