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Original Article

A comparative study of anti-inflammatory and antidyslipidemic effects of fenofibrate and statins on rheumatoid arthritis

Pages 238-243 | Received 29 Sep 2009, Accepted 25 Nov 2009, Published online: 02 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ehab Mudher Mikhael. (2020) Is fenofibrate the missing piece in COVID-19 management?. Alexandria Journal of Medicine 56:1, pages 132-133.
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Hsien-Feng Lin, Kuan-Fu Liao, Ching-Mei Chang, Cheng-Li Lin & Shih-Wei Lai. (2017) Statin use correlates with reduced risk of chronic osteomyelitis: a nationwide case–control study in Taiwan. Current Medical Research and Opinion 33:12, pages 2235-2240.
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Matthias Hecker, Aniella Behnk, Rory Edward Morty, Natascha Sommer, István Vadász, Susanne Herold, Werner Seeger & Konstantin Mayer. (2015) PPAR-α activation reduced LPS-induced inflammation in alveolar epithelial cells. Experimental Lung Research 41:7, pages 393-403.
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Articles from other publishers (13)

Lucreţia Udrescu, Paul Bogdan, Aimée Chiş, Ioan Ovidiu Sîrbu, Alexandru Topîrceanu, Renata-Maria Văruţ & Mihai Udrescu. (2020) Uncovering New Drug Properties in Target-Based Drug–Drug Similarity Networks. Pharmaceutics 12:9, pages 879.
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Zuo, Prather, Stetskiv, Garrison, Meade, Peace & Zhou. (2019) Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments. International Journal of Molecular Sciences 20:18, pages 4472.
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Rosa Vitale, Enrico D'Aniello, Stefania Gorbi, Andrea Martella, Cristoforo Silvestri, Maria Giuliani, Tariq Fellous, Alessandra Gentile, Marianna Carbone, Adele Cutignano, Laura Grauso, Laura Magliozzi, Gianluca Polese, Biagio D'Aniello, Fanny Defranoux, Serena Felline, Antonio Terlizzi, Antonio Calignano, Francesco Regoli, Vincenzo Di Marzo, Pietro Amodeo & Ernesto Mollo. (2018) Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest. Marine Drugs 16:11, pages 431.
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G. Shyam Prasad, P. Govardhan, G. Deepika, V. Vakdevi & R. B. Sashidhar. (2017) Anti-inflammatory activity of anti-hyperlipidemic drug, fenofibrate, and its phase-I metabolite fenofibric acid: in silico, in vitro, and in vivo studies. Inflammopharmacology 26:4, pages 973-981.
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Ying Cao, Jianbo Cao, Binbin Yu, Shusheng Wang, Lili Liu, Li Tao & Wanping Sun. (2017) Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway. Experimental and Therapeutic Medicine.
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P.S. Kharkar, S. Borhade, A. Dangi & S. Warrier. (2015) In search of novel anti-inflammatory agents: Computational repositioning of approved drugs. Journal of Computational Science 10, pages 217-224.
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Janaína K. Barbiero, Ronise M. Santiago, Daniele Suzete Persike, Maria José da Silva Fernandes, Fernanda S. Tonin, Claudio da Cunha, Suelen Lucio Boschen, Marcelo M.S. Lima & Maria A.B.F. Vital. (2014) Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine. Behavioural Brain Research 274, pages 390-399.
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Nicola Ferri & Alberto Corsini. (2014) Clinical evidence of statin therapy in non-dyslipidemic disorders. Pharmacological Research 88, pages 20-30.
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Ivan V. Shirinsky & Valery S. Shirinsky. (2013) Treatment of erosive osteoarthritis with peroxisome proliferator-activated receptor alpha agonist fenofibrate: a pilot study. Rheumatology International 34:5, pages 613-616.
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Chul-Su Yang, Jae-Min Yuk, Jwa-Jin Kim, Jung Hwan Hwang, Chul-Ho Lee, Jin-Man Kim, Goo Taeg Oh, Hueng-Sik Choi & Eun-Kyeong Jo. (2013) Small Heterodimer Partner-Targeting Therapy Inhibits Systemic Inflammatory Responses through Mitochondrial Uncoupling Protein 2. PLoS ONE 8:5, pages e63435.
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Inge C.M. van Eekeren, Stefan Clockaerts, Yvonne M. Bastiaansen-Jenniskens, Eric Lubberts, Jan A.N. Verhaar, Gerjo J.V.M. van Osch & Sita M. Bierma-Zeinstra. (2013) Fibrates as therapy for osteoarthritis and rheumatoid arthritis? A systematic review. Therapeutic Advances in Musculoskeletal Disease 5:1, pages 33-44.
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Jiatao Ye, James N Kiage, Donna K Arnett, Alfred A Bartolucci & Edmond K Kabagambe. (2011) Short-term effect of fenofibrate on C-reactive protein: A meta-analysis of randomized controlled trials. Diabetology & Metabolic Syndrome 3:1.
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Estíbaliz CastilleroMaría Paz Nieto-Bona, Carmen Fernández-GalazAna Isabel MartínMaría López-MenduiñaMiriam Granado, María Angeles VillanúaAsunción López-Calderón. (2011) Fenofibrate, a PPARα agonist, decreases atrogenes and myostatin expression and improves arthritis-induced skeletal muscle atrophy. American Journal of Physiology-Endocrinology and Metabolism 300:5, pages E790-E799.
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