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Original Article

Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes

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Pages 104-111 | Received 29 Nov 2011, Accepted 08 Mar 2012, Published online: 02 Jan 2014

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Yoshiaki Suzuki, Masahiro Hasegawa, Yuriyo Matsui, Hironori Unno, Takahiro Iino, Toshimichi Yoshida & Akihiro Sudo. (2020) Intra-articular injection of rebamipide prevents articular cartilage degeneration in murine post-traumatic osteoarthritis models. Modern Rheumatology 30:4, pages 765-772.
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Articles from other publishers (20)

Tiantian Tian, Chung-Nga Ko, Wenya Luo, Dan Li & Chao Yang. (2023) The anti-aging mechanism of ginsenosides with medicine and food homology. Food & Function 14:20, pages 9123-9136.
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Hongtao Li, Xiaoqiang Wang, Hongyu Pan, Changming Xiao, Chenglong Wang, Sheng Guo, Longhai Long, Houyin Shi, Hui Chen & Sen Li. (2023) The mechanisms and functions of IL-1β in intervertebral disc degeneration. Experimental Gerontology 177, pages 112181.
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Wen-Tao Sun, Cindy L. H. Yang, Terry C. T. Or, Dan Luo & James C. B. Li. (2022) Ginsenoside Rb1 from Panax notoginseng Suppressed TNF-α-Induced Matrix Metalloproteinase-9 via the Suppression of Double-Strand RNA-Dependent Protein Kinase (PKR)/NF-κB Pathway. Molecules 27:22, pages 8050.
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Ching-Hou Ma, Wan-Ching Chou, Chin-Hsien Wu, I-Ming Jou, Yuan-Kun Tu, Pei-Ling Hsieh & Kun-Ling Tsai. (2021) Ginsenoside Rg3 Attenuates TNF-α-Induced Damage in Chondrocytes through Regulating SIRT1-Mediated Anti-Apoptotic and Anti-Inflammatory Mechanisms. Antioxidants 10:12, pages 1972.
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Ha-Ri Lee, Joon Min Jung, Ji-Yeon Seo, Sung Eun Chang & Youngsup Song. (2021) Anti-melanogenic property of ginsenoside Rf from Panax ginseng via inhibition of CREB/MITF pathway in melanocytes and ex vivo human skin. Journal of Ginseng Research 45:5, pages 555-564.
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Yongjie Wang, Mingxue Che, Jingguo Xin, Zhi Zheng, Jiangbi Li & Shaokun Zhang. (2020) The role of IL-1β and TNF-α in intervertebral disc degeneration. Biomedicine & Pharmacotherapy 131, pages 110660.
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Linzi Han, Yuying Zhang, Mingming Zhang, Liyu Guo, Jun Wang, Fanjun Zeng, Deping Xu, Zongzhi Yin, Yuanhong Xu, Deguang Wang & Haisheng Zhou. (2020) Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells. Kidney and Blood Pressure Research 45:2, pages 314-330.
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Young-Su Yi. (2019) Ameliorative effects of ginseng and ginsenosides on rheumatic diseases. Journal of Ginseng Research 43:3, pages 335-341.
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Yoo Kyoung Han, Seo Yul Kim, Jae Young Ahn & Jin Ung Baek. (2017) An analysis of the combination frequencies of constituent medicinal herbs in prescriptions for the treatment of bone and joint disorder in Korean medicine: determination of a group of candidate prescriptions for universal use. Integrative Medicine Research.
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Y. Fu, Z.-H. Yin & C.-Y. Yin. (2017) Biotransformation of ginsenoside Rb1 to ginsenoside Rg3 by endophytic bacterium Burkholderia sp. GE 17-7 isolated from Panax ginseng . Journal of Applied Microbiology 122:6, pages 1579-1585.
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Emeric Limagne, Allan Lançon, Dominique Delmas, Mustapha Cherkaoui-Malki & Norbert Latruffe. (2016) Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages. Nutrients 8:5, pages 280.
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Mauro Provinciali, Elisa Pierpaoli, Francesco Piacenza, Robertina Giacconi, Laura Costarelli, Andrea Basso, Rina Recchioni, Fiorella Marcheselli, Dorothy Bray, Khadija Benlhassan & Marco Malavolta. 2016. Molecular Basis of Nutrition and Aging. Molecular Basis of Nutrition and Aging 293 312 .
Wei Yang, Xiao-Hua Yu, Cheng Wang, Wen-Si He, Shu-Jun Zhang, Yi-Guo Yan, Jian Zhang, Yong-Xiao Xiang & Wen-Jun Wang. (2015) Interleukin-1β in intervertebral disk degeneration. Clinica Chimica Acta 450, pages 262-272.
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Seung Jae Lee, Woo Jin Lee, Sung Eun Chang & Ga-Young Lee. (2015) Antimelanogenic effect of ginsenoside Rg3 through extracellular signal-regulated kinase-mediated inhibition of microphthalmia-associated transcription factor. Journal of Ginseng Research 39:3, pages 238-242.
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Yun Jong LeeKye Yong SongEun Young LeeHeun Soo KangYeong Wook Song. (2015) Compound K, a Metabolite of Ginsenosides, Attenuates Collagen-induced Arthritis in Mice. Journal of Rheumatic Diseases 22:3, pages 154.
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Je Hyeong Lee, Omer Shehzad, Sung Kwon Ko, Yeong Shik Kim & Hyun Pyo Kim. (2015) Matrix metalloproteinase-13 downregulation and potential cartilage protective action of the Korean Red Ginseng preparation. Journal of Ginseng Research 39:1, pages 54-60.
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Marco Malavolta, Laura Costarelli, Robertina Giacconi, Francesco Piacenza, Andrea Basso, Elisa Pierpaoli, Francesca Marchegiani, Maurizio Cardelli, Mauro Provinciali & Eugenio Mocchegiani. (2014) Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds. Nutrition Research 34:12, pages 1017-1035.
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Yi Zhu, Jacqueline L. Armstrong, Tamara Tchkonia & James L. Kirkland. (2014) Cellular senescence and the senescent secretory phenotype in age-related chronic diseases. Current Opinion in Clinical Nutrition and Metabolic Care 17:4, pages 324-328.
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Yumin Huang, Dongying Wu & Weimin Fan. (2014) Protection of ginsenoside Rg1 on chondrocyte from IL-1β-induced mitochondria-activated apoptosis through PI3K/Akt signaling. Molecular and Cellular Biochemistry 392:1-2, pages 249-257.
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Je Hyeong Lee, Hyun Lim, Omer Shehzad, Yeong Shik Kim & Hyun Pyo Kim. (2014) Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation. European Journal of Pharmacology 724, pages 145-151.
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