1,453
Views
39
CrossRef citations to date
0
Altmetric
Original Article

Quality of life benefits and cost impact of prolonged release oxycodone/naloxone versus prolonged release oxycodone in patients with moderate-to-severe non-malignant pain and opioid-induced constipation: a UK cost-utility analysis

, , , &
Pages 564-575 | Accepted 06 Feb 2012, Published online: 23 Feb 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Wojciech Leppert, Renata Zajaczkowska & Jerzy Wordliczek. (2019) The role of oxycodone/naloxone in the management of patients with pain and opioid-induced constipation. Expert Opinion on Pharmacotherapy 20:5, pages 511-522.
Read now
Carsten Bantel, Shiva S Tripathi, David Molony, Tony Heffernan, Susmita Oomman, Vivek Mehta & Sara Dickerson. (2018) Prolonged-release oxycodone/naloxone reduces opioid-induced constipation and improves quality of life in laxative-refractory patients: results of an observational study. Clinical and Experimental Gastroenterology 11, pages 57-67.
Read now
Joseph V Pergolizzi$suffix/text()$suffix/text(), Robert B Raffa, Marco Pappagallo, Charles Fleischer, Joseph Pergolizzi$suffix/text()$suffix/text(), Gianpietro Zampogna, Elizabeth Duval, Janan Hishmeh, Jo Ann LeQuang & Robert Taylor$suffix/text()$suffix/text(). (2017) Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy. Patient Preference and Adherence 11, pages 107-119.
Read now
Stefano De Santis, Cristina Borghesi, Serena Ricciardi, Daniele Giovannoni, Alberto Fulvi, Maria Rita Migliorino & Claudio Marcassa. (2016) Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain: an observational analysis. OncoTargets and Therapy 9, pages 4043-4052.
Read now
Gineke Koopmans-Klein, Michel F.M. Wagemans, Hans C.H. Wartenberg, Yvonne J.B. Van Megen & Frank J.P.M. Huygen. (2016) The efficacy of standard laxative use for the prevention and treatment of opioid induced constipation during oxycodone use: a small Dutch observational pilot study. Expert Review of Gastroenterology & Hepatology 10:4, pages 547-553.
Read now
Wojciech Leppert. (2015) Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction. Drug Design, Development and Therapy 9, pages 2215-2231.
Read now
Sandra L. Kane-Gill, Ellen C. Rubin, Pamela L. Smithburger, Mitchell S. Buckley & Joseph F. Dasta. (2014) The Cost of Opioid-Related Adverse Drug Events. Journal of Pain & Palliative Care Pharmacotherapy 28:3, pages 282-293.
Read now
M. Lazzari, A. F. Sabato, C. Caldarulo, M. Casali, P. Gafforio, C. Marcassa & F. Leonardis. (2014) Effectiveness and tolerability of low-dose oral oxycodone/naloxone added to anticonvulsant therapy for noncancer neuropathic pain: an observational analysis. Current Medical Research and Opinion 30:4, pages 555-564.
Read now
Mellar Davis, Harold W Goforth & Pam Gamier. (2013) Oxycodone combined with opioid receptor antagonists: efficacy and safety. Expert Opinion on Drug Safety 12:3, pages 389-402.
Read now
Sebastiano Mercadante & Antonello Giarratano. (2013) Combined oral prolonged-release oxycodone and naloxone in chronic pain management. Expert Opinion on Investigational Drugs 22:1, pages 161-166.
Read now

Articles from other publishers (27)

Rong Ouyang, Zhongzhuan Li, Shijiang Huang, Jun Liu & Jiean Huang. (2020) Efficacy and Safety of Peripherally Acting Mu-Opioid Receptor Antagonists for the Treatment of Opioid-Induced Constipation: A Bayesian Network Meta-analysis. Pain Medicine 21:11, pages 3224-3232.
Crossref
Insa Backhaus, Alice Mannocci & Giuseppe La Torre. (2019) A Systematic Review of Economic Evaluation Studies of Drug-Based Non-Malignant Chronic Pain Treatment. Current Pharmaceutical Biotechnology 20:11, pages 910-919.
Crossref
Pavit Luthra, Nicholas E Burr, Darren M Brenner & Alexander C Ford. (2019) Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis. Gut 68:3, pages 434-444.
Crossref
Adam D Farmer, Asbjørn M Drewes, Giuseppe Chiarioni, Roberto De Giorgio, Tony O'Brien, Bart Morlion & Jan Tack. (2019) Pathophysiology and management of opioid‐induced constipation: European expert consensus statement. United European Gastroenterology Journal 7:1, pages 7-20.
Crossref
Bart J. Morlion, Stefan A. Mueller‐Lissner, Renato Vellucci, Wojciech Leppert, Benoît C. Coffin, Sara L. Dickerson & Tony O'Brien. (2017) Oral Prolonged‐Release Oxycodone/Naloxone for Managing Pain and Opioid‐Induced Constipation: A Review of the Evidence. Pain Practice 18:5, pages 647-665.
Crossref
Adam D Farmer, Caroline Bruckner Holt, Thomas J Downes, Eugenio Ruggeri, Sara Del Vecchio & Roberto De Giorgio. (2018) Pathophysiology, diagnosis, and management of opioid-induced constipation. The Lancet Gastroenterology & Hepatology 3:3, pages 203-212.
Crossref
Esther S. Kim. (2017) Oxycodone/Naloxone Prolonged Release: A Review in Severe Chronic Pain. Clinical Drug Investigation 37:12, pages 1191-1201.
Crossref
Asbjørn Mohr Drewes. (2017) Opioids and the gut; not only constipation and laxatives. Scandinavian Journal of Pain 15:1, pages 81-82.
Crossref
Richard Lawson, James Ryan, Frederic King, Jo Wern Goh, Eszter Tichy & Kevin Marsh. (2016) Cost Effectiveness of Naloxegol for Opioid-Induced Constipation in the UK. PharmacoEconomics 35:2, pages 225-235.
Crossref
Magdalena Kocot-KępskaRenata ZajączkowskaAnna Przeklasa-MuszyńskaJan Dobrogowski. (2017) The role of oxycodone/naloxone in pain management. BÓL 17:4, pages 26-40.
Crossref
Stefan Müller-Lissner, Gabrio Bassotti, Benoit Coffin, Asbjørn Mohr Drewes, Harald Breivik, Elon Eisenberg, Anton Emmanuel, Françoise Laroche, Winfried Meissner & Bart Morlion. (2016) Opioid-Induced Constipation and Bowel Dysfunction: A Clinical Guideline. Pain Medicine, pages pnw255.
Crossref
Anthony James Hatswell & Stefan Vegter. (2016) Measuring quality of life in opioid-induced constipation: mapping EQ-5D-3 L and PAC-QOL. Health Economics Review 6:1.
Crossref
Frida Hjalte, Gunnel Ragnarson Tennvall, Karl-Olof Welin & Dagmar Westerling. (2016) Treatment of Severe Pain and Opioid-induced Constipation: An Observational Study of Quality of Life, Resource Use, and Costs in Sweden. Pain and Therapy 5:2, pages 227-236.
Crossref
W. Sullivan, M. Hirst, S. Beard, D. Gladwell, F. Fagnani, J. López Bastida, C. Phillips & W. C. N. Dunlop. (2015) Economic evaluation in chronic pain: a systematic review and de novo flexible economic model. The European Journal of Health Economics 17:6, pages 755-770.
Crossref
Claudia Trenkwalder, K Ray Chaudhuri, Pablo Martinez-Martin, Olivier Rascol, Reinhard Ehret, Martin Vališ, Maria Sátori, Anna Krygowska-Wajs, Maria J Marti, Karen Reimer, Alexander Oksche, Mark Lomax, Julia DeCesare & Michael Hopp. (2015) Prolonged-release oxycodone–naloxone for treatment of severe pain in patients with Parkinson's disease (PANDA): a double-blind, randomised, placebo-controlled trial. The Lancet Neurology 14:12, pages 1161-1170.
Crossref
Lourdes Ferreira Laso, Amanda López Picado, Fernando Antoñanzas Villar, Laura Lamata de la Orden, Mar Ceballos Garcia, Carolina Ibañez López, Lorena Pipaon Ruilope, Felix Lamata Hernandez, Cesar Valero Martinez, Felipe Aizpuru & Roberto Hernandez Chaves. (2015) Cost-Effectiveness Analysis of Levobupivacaine 0.5 %, a Local Anesthetic, Infusion in the Surgical Wound After Modified Radical Mastectomy. Clinical Drug Investigation 35:9, pages 575-582.
Crossref
G. S. Sagoo, S. Mohammed, G. Barton, G. Norbury, J. W. Ahn, C. M. Ogilvie & M. Kroese. (2015) Cost Effectiveness of Using Array-CGH for Diagnosing Learning Disability. Applied Health Economics and Health Policy 13:4, pages 421-432.
Crossref
Bart Morlion, Katri Elina Clemens & Will Dunlop. (2014) Quality of Life and Healthcare Resource in Patients Receiving Opioids for Chronic Pain: A Review of the Place of Oxycodone/Naloxone. Clinical Drug Investigation 35:1, pages 1-11.
Crossref
Iftekhar Khan & Stephen Morris. (2014) A non-linear beta-binomial regression model for mapping EORTC QLQ- C30 to the EQ-5D-3L in lung cancer patients: a comparison with existing approaches. Health and Quality of Life Outcomes 12:1.
Crossref
Arturo Cuomo, Gennaro Russo, Gennaro Esposito, Cira Antonietta Forte, Marianna Connola & Claudio Marcassa. (2013) Efficacy and Gastrointestinal Tolerability of Oral Oxycodone/Naloxone Combination for Chronic Pain in Outpatients With Cancer. American Journal of Hospice and Palliative Medicine® 31:8, pages 867-876.
Crossref
V. C. P. C. Dongen, P. J. L. Vanelderen, G. Koopmans‐Klein, Y. J. B. Megen, J. Van Zundert & F. J. P. M. Huygen. (2014) Patient preference with respect to QoL and reduction in opioid‐induced constipation ( OIC ) after treatment with prolonged‐release ( PR ) oxycodone/naloxone compared with previous analgesic therapy [ PREFER study] . International Journal of Clinical Practice 68:11, pages 1364-1375.
Crossref
Anne Z. DePriest & Katie Miller. (2014) Oxycodone/Naloxone: Role in Chronic Pain Management, Opioid-Induced Constipation, and Abuse Deterrence. Pain and Therapy 3:1, pages 1-15.
Crossref
Celeste B. Burness & Gillian M. Keating. (2014) Oxycodone/Naloxone Prolonged-Release: A Review of Its Use in the Management of Chronic Pain While Counteracting Opioid-Induced Constipation. Drugs 74:3, pages 353-375.
Crossref
Richard J. Bodnar. (2013) Endogenous opiates and behavior: 2012. Peptides 50, pages 55-95.
Crossref
Alexander C Ford, Darren M Brenner & Philip S Schoenfeld. (2013) Efficacy of Pharmacological Therapies for the Treatment of Opioid-Induced Constipation: Systematic Review and Meta-Analysis. American Journal of Gastroenterology 108:10, pages 1566-1574.
Crossref
Antonio Gatti, Manuela Casali, Marzia Lazzari, Giuseppe Tufaro, Paolo Gafforio, Claudia Silvestri, Claudio Marcassa & Alessandro F. Sabato. (2012) Prolonged-Release Oxycodone/Naloxone in Nonmalignant Pain: Single-Center Study in Patients with Constipation. Advances in Therapy 30:1, pages 41-59.
Crossref
Guido Schneider, Raymond Voltz & Jan Gaertner. (2012) Cancer Pain Management and Bone Metastases: An Update for the Clinician. Breast Care 7:2, pages 113-120.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.