Advanced search
Publication Cover
Dialogues in Clinical Neuroscience Volume 11, 2009 - Issue 4
Submit an article Journal homepage
672
Views
48
CrossRef citations to date
0
Altmetric
Pharmacological Aspects

Major depression during interferon-α treatment: vulnerability and prevention

Depresión mayor durante el tratamiento con α-interferón: vulnerabilidad y prevención

Dépression majeure au cours d'un traitement par interféron-α: ulnérabilité et prévention

Francis E. LotrichWestern Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USACorrespondence[email protected]
Pages 417-425 | Published online: 01 Apr 2022

Citations (48)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Kimberley J Smith, Suzanne Norris, Cliona O’Farrelly & Shane M O’Mara. (2011) Risk factors for the development of depression in patients with hepatitis C taking interferon-α. Neuropsychiatric Disease and Treatment 7, pages 275-292.
Read now

Articles from other publishers (47)

Karl Savonije, Autumn Meek & Donald F. Weaver. (2023) Indoleamine 2,3-Dioxygenase as a Therapeutic Target for Alzheimer’s Disease and Geriatric Depression. Brain Sciences 13:6, pages 852.
Crossref
K. Yu. Kalitin, A. A. Spasov & O. Yu. Mukha. (2023) Models of neuroinflammation for the assessment of kappa-opioid receptor ligands. Pharmacy & Pharmacology 11:1, pages 4-18.
Crossref
Kristen K. Baumann, W. Sandy Liang, Daniel V. Quaranta, Miranda L. Wilson, Helina S. Asrat, Jarl A. Thysell, Angelo V. Sarchi, William A. Banks & Michelle A. Erickson. (2023) Effects of Ozone on Sickness and Depressive-like Behavioral and Biochemical Phenotypes and Their Regulation by Serum Amyloid A in Mice. International Journal of Molecular Sciences 24:2, pages 1612.
Crossref
Rose E. Presby, Renee A. Rotolo, Sydney Katz, Zoha Sarwat, Merce Correa & John D. Salamone. (2023) Lipopolysaccharide-induced changes in effort-related motivational function: Interactions with 2-deoxyglucose. Physiology & Behavior 258, pages 114005.
Crossref
Shayam Suseelan & Graziano Pinna. 2023. 1 67 .
Barbara Polityńska, Olga Pokorska, Anna M. Wojtukiewicz, Magdalena Sawicka, Marta Myśliwiec, Kenneth V. Honn, Stephanie C. Tucker & Marek Z. Wojtukiewicz. (2022) Is depression the missing link between inflammatory mediators and cancer?. Pharmacology & Therapeutics 240, pages 108293.
Crossref
Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Bright S. Addy, Sian Lant, Rebecca P. Sumner, Carlos Maluquer de Motes, Gordon A. Awandare, Charles Ansah & Mohamed Mutocheluh. (2022) The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways. Journal of Immunology Research 2022, pages 1-13.
Crossref
Steven E. Massey. (2021) Host Manipulation Mechanisms of SARS-CoV-2. Acta Biotheoretica 70:1.
Crossref
Hyunjung Oh, Dwight Newton, David Lewis & Etienne Sibille. (2022) Lower Levels of GABAergic Function Markers in Corticotropin-Releasing Hormone-Expressing Neurons in the sgACC of Human Subjects With Depression. Frontiers in Psychiatry 13.
Crossref
Galen Missig, Emma L. Fritsch, Niyati Mehta, Miles E. Damon, Erica M. Jarrell, Andrew A. Bartlett, F. Ivy Carroll & William A. CarlezonJrJr. (2022) Blockade of kappa-opioid receptors amplifies microglia-mediated inflammatory responses. Pharmacology Biochemistry and Behavior 212, pages 173301.
Crossref
Noha Althubaity, Julia Schubert, Daniel Martins, Tayyabah Yousaf, Maria A. Nettis, Valeria Mondelli, Carmine Pariante, Neil A. Harrison, Edward T. Bullmore, Danai Dima, Federico E. Turkheimer & Mattia Veronese. (2022) Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression. NeuroImage: Clinical 33, pages 102926.
Crossref
Alish B. Palmos, Raymond Chung, Souci Frissa, Laura Goodwin, Matthew Hotopf, Stephani L. Hatch, Gerome Breen & Timothy R. Powell. (2021) Reconsidering the reasons for heightened inflammation in major depressive disorder. Journal of Affective Disorders 282, pages 434-441.
Crossref
Aleksander Nobis, Daniel Zalewski & Napoleon Waszkiewicz. (2020) Peripheral Markers of Depression. Journal of Clinical Medicine 9:12, pages 3793.
Crossref
Benjamin M. Seitz, Athena AktipisDavid M. BussJoe AlcockPaul BloomMichele Gelfand, Sam HarrisDebra Lieberman, Barbara N. HorowitzSteven Pinker, David Sloan Wilson & Martie G. Haselton. (2020) The pandemic exposes human nature: 10 evolutionary insights. Proceedings of the National Academy of Sciences 117:45, pages 27767-27776.
Crossref
Joel T. Parkinson, Éimear M. Foley, Deepak R. Jadon & Golam M. Khandaker. (2020) Depression in patients with spondyloarthritis: prevalence, incidence, risk factors, mechanisms and management. Therapeutic Advances in Musculoskeletal Disease 12, pages 1759720X2097002.
Crossref
Svetlana Frenkel, Charles N. Bernstein, Michael Sargent, Wenxin Jiang, Qin Kuang, Wei Xu & Pingzhao Hu. (2020) Copy number variation-based gene set analysis reveals cytokine signalling pathways associated with psychiatric comorbidity in patients with inflammatory bowel disease. Genomics 112:1, pages 683-693.
Crossref
Alessia Mastrodonato, Omid Cohensedgh, Christina T. LaGamma, Josephine C. McGowan, Holly C. Hunsberger & Christine A. Denny. (2020) Prophylactic (R,S)-ketamine selectively protects against inflammatory stressors. Behavioural Brain Research 378, pages 112238.
Crossref
Bogna Grygiel‐Górniak, Nattakarn Limphaibool & Mariusz Puszczewicz. (2019) Cytokine secretion and the risk of depression development in patients with connective tissue diseases. Psychiatry and Clinical Neurosciences 73:6, pages 302-316.
Crossref
Daniyal Aleem & Hassaan Tohid. (2018) Pro-inflammatory Cytokines, Biomarkers, Genetics and the Immune System: A Mechanistic Approach of Depression and Psoriasis. Revista Colombiana de Psiquiatría (English ed.) 47:3, pages 177-186.
Crossref
Daniyal Aleem & Hassaan Tohid. (2018) Pro-inflammatory Cytokines, Biomarkers, Genetics and the Immune System: A Mechanistic Approach of Depression and Psoriasis. Revista Colombiana de Psiquiatría 47:3, pages 177-186.
Crossref
Błażej Misiak, Jan Aleksander Beszłej, Kamila Kotowicz, Monika Szewczuk-Bogusławska, Jerzy Samochowiec, Jolanta Kucharska-Mazur & Dorota Frydecka. (2018) Cytokine alterations and cognitive impairment in major depressive disorder: From putative mechanisms to novel treatment targets. Progress in Neuro-Psychopharmacology and Biological Psychiatry 80, pages 177-188.
Crossref
Giulia Malaguarnera, Gaetano Bertino, Carmela Greco, Caterina Gagliano, Massimo Motta, Giuseppe Chisari, Venerando Rapisarda, Giuseppe Nunnari, Michele Vecchio, Filippo Drago & Michele Malaguarnera. (2017) Job performance in chronic hepatitis C virus patients treated with pegylated interferon-α2b plus ribavirin: an observational study. Translational Medicine Communications 2:1.
Crossref
Charles L Raison & Andrew H Miller. (2016) Pathogen–Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance. Neuropsychopharmacology 42:1, pages 5-27.
Crossref
Samantha E. Yohn, Yumna Arif, Allison Haley, Guiseppe Tripodi, Younis Baqi, Christa E. Müller, Noemi San Miguel, Mercè Correa & John D. Salamone. (2016) Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization. Psychopharmacology 233:19-20, pages 3575-3586.
Crossref
John D. Salamone, Samantha E. Yohn, Laura López-Cruz, Noemí San Miguel & Mercè Correa. (2016) Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology. Brain 139:5, pages 1325-1347.
Crossref
Francis E. Lotrich, Barry Sears & Robert K. McNamara. (2016) Polyunsaturated fatty acids moderate the effect of poor sleep on depression risk. Prostaglandins, Leukotrienes and Essential Fatty Acids 106, pages 19-25.
Crossref
Proteesh Rana, Amit K. Sharma, Smita Jain, Pravin Deshmukh, S.K. Bhattacharya, B.D. Banerjee & Pramod K. Mediratta. (2016) Comparison of fluoxetine and 1-methyl-L-tryptophan in treatment of depression-like illness in Bacillus Calmette-Guerin-induced inflammatory model of depression in mice. Journal of Basic and Clinical Physiology and Pharmacology 27:6.
Crossref
Charles L. Raison. 2017. Inflammation-Associated Depression: Evidence, Mechanisms and Implications. Inflammation-Associated Depression: Evidence, Mechanisms and Implications 287 302 .
Isabelle Granville Smith, Gordon Parker, Erin Cvejic & Uté Vollmer-Conna. (2015) Acute coronary syndrome-associated depression: The salience of a sickness response analogy?. Brain, Behavior, and Immunity 49, pages 18-24.
Crossref
Laurence Zitvogel, Lorenzo Galluzzi, Oliver Kepp, Mark J. Smyth & Guido Kroemer. (2015) Type I interferons in anticancer immunity. Nature Reviews Immunology 15:7, pages 405-414.
Crossref
David J Allison & David S Ditor. (2014) The common inflammatory etiology of depression and cognitive impairment: a therapeutic target. Journal of Neuroinflammation 11:1.
Crossref
Viktoria Stelzhammer, Frieder Haenisch, Man K. Chan, Jason D. Cooper, Johann Steiner, Hannah Steeb, Daniel Martins-de-Souza, Hassan Rahmoune, Paul C. Guest & Sabine Bahn. (2014) Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients. The International Journal of Neuropsychopharmacology 17:10, pages 1599-1608.
Crossref
Alicia K. Smith, Karen N. Conneely, Thaddeus W.W. Pace, Donna Mister, Jennifer C. Felger, Varun Kilaru, Mary J. Akel, Paula M. Vertino, Andrew H. Miller & Mylin A. Torres. (2014) Epigenetic changes associated with inflammation in breast cancer patients treated with chemotherapy. Brain, Behavior, and Immunity 38, pages 227-236.
Crossref
Rachel H.B. Mitchell & Benjamin I. Goldstein. (2014) Inflammation in Children and Adolescents With Neuropsychiatric Disorders: A Systematic Review. Journal of the American Academy of Child & Adolescent Psychiatry 53:3, pages 274-296.
Crossref
Flavia Macchi, Judith R Homberg, Francesca Calabrese, Claudia Zecchillo, Giorgio Racagni, Marco A Riva & Raffaella Molteni. (2013) Altered inflammatory responsiveness in serotonin transporter mutant rats. Journal of Neuroinflammation 10:1.
Crossref
Pramudie Gunaratne, Andrew R Lloyd & Ute Vollmer-Conna. (2013) Mood disturbance after infection. Australian & New Zealand Journal of Psychiatry 47:12, pages 1152-1164.
Crossref
Francis E. Lotrich, Barry Sears & Robert K. McNamara. (2013) Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids. Journal of Psychosomatic Research 75:5, pages 475-483.
Crossref
J.C. Felger & F.E. Lotrich. (2013) Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications. Neuroscience 246, pages 199-229.
Crossref
Francis E Lotrich, Salwa Albusaysi & Robert E Ferrell. (2012) Brain-Derived Neurotrophic Factor Serum Levels and Genotype: Association with Depression during Interferon-α Treatment. Neuropsychopharmacology 38:6, pages 985-995.
Crossref
Bernardo Dell'OssoGianmaria PratiM. Carlotta PalazzoMaria Grazia RumiFlaminia CavallaroAlessio AghemoMassimo ColomboA. Carlo Altamura. (2013) Predictors of Psychopathological Outcome During Peg-Interferon and Ribavirin Therapy in Patients with Chronic HCV-Correlated Hepatitis. Journal of Interferon & Cytokine Research 33:1, pages 9-14.
Crossref
J. C. Felger, S. W. Cole, T. W. W. Pace, F. Hu, B. J. Woolwine, G. H. Doho, C. L. Raison & A. H. Miller. (2011) Molecular signatures of peripheral blood mononuclear cells during chronic interferon-α treatment: relationship with depression and fatigue. Psychological Medicine 42:8, pages 1591-1603.
Crossref
Charles F. ReynoldsIIIIIIPim Cuijpers, Vikram Patel, Alex Cohen, Amit Dias, Neerja Chowdhary, Olivia I. Okereke, Mary Amanda DewStewart J. AndersonSati MazumdarFrank LotrichSteven M. Albert. (2012) Early Intervention to Reduce the Global Health and Economic Burden of Major Depression in Older Adults. Annual Review of Public Health 33:1, pages 123-135.
Crossref
D Martins-de-Souza, P C Guest, L W Harris, N Vanattou-Saifoudine, M J Webster, H Rahmoune & S Bahn. (2012) Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients. Translational Psychiatry 2:3, pages e87-e87.
Crossref
Mauro García-Toro, Angels Vilella Martorell, María Carral Martínez, Teresa Jimeno Beltrán, Yolanda Román Ruiz del Moral, Carmen Pradas Guerrero, Margalida Gili Planas & Miguel Roca Bennasar. (2011) Uso de ansiolíticos y antidepresivos pre y postratamiento con interferón-alfa y ribavirina en pacientes con hepatitis C. Gastroenterología y Hepatología 34:4, pages 307-308.
Crossref
Karen Wager-Smith & Athina Markou. (2011) Depression: A repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?. Neuroscience & Biobehavioral Reviews 35:3, pages 742-764.
Crossref
Yara Dadalti Fragoso, Elizabeth Regina Comini Frota, Juarez Silva Lopes, Janaina Silveira Noal, Maria Cristina Giacomo, Sidney Gomes, Marcus Vinicius Magno Gonçalves, Paulo Diniz da Gama & Alessandro Finkelsztejn. (2010) Severe Depression, Suicide Attempts, and Ideation During the Use of Interferon Beta by Patients With Multiple Sclerosis. Clinical Neuropharmacology 33:6, pages 312-316.
Crossref
Francis Lotrich. (2010) Management of Psychiatric Disease in Hepatitis C Treatment Candidates. Current Hepatitis Reports 9:2, pages 113-118.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.