Advanced search
Publication Cover
Postgraduate Medicine Volume 126, 2014 - Issue 7
Submit an article Journal homepage
417
Views
56
CrossRef citations to date
0
Altmetric
Clinical Focus: Thrombosis and Cardiovascular Medicine

Overview of Prescription Omega-3 Fatty Acid Products for Hypertriglyceridemia

Howard S. Weintraub Clinical Professor of Medicine, New York University School of Medicine, Clinical Director, NYU Center for the Prevention of Cardiovascular Disease, New York, NYCorrespondence[email protected]
, MD
Pages 7-18 | Published online: 13 Mar 2015

Citations (56)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Samuel N Uwaezuoke, Uzoamaka V Muoneke & Ngozi R Mbanefo. (2020) The Supportive Treatment of IgA Nephropathy and Idiopathic Nephrotic Syndrome: How Useful are Omega-3 Polyunsaturated Fatty Acids?. International Journal of Nephrology and Renovascular Disease 13, pages 27-35.
Read now
Najdat Bazarbashi & Michael Miller. (2020) Icosapent ethyl: drug profile and evidence of reduced residual cardiovascular risk in patients with statin-managed LDL-C cholesterol. Expert Review of Cardiovascular Therapy 18:4, pages 175-180.
Read now
Peter P Toth. (2016) Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease. Vascular Health and Risk Management 12, pages 171-183.
Read now
James R. Crandell, Christina Tartaglia & Joseph Tartaglia. (2016) Lipid effects of switching from prescription EPA+DHA (omega-3-acid ethyl esters) to prescription EPA only (icosapent ethyl) in dyslipidemic patients. Postgraduate Medicine 128:8, pages 859-864.
Read now
Eduardo Filipe Oliveira, Diogo Santos-Martins, António Meireles Ribeiro, Natércia Fernandes Brás, Nuno Sousa Cerqueira, Sérgio Filipe Sousa, Maria João Ramos & Pedro Alexandrino Fernandes. (2016) HMG-CoA Reductase inhibitors: an updated review of patents of novel compounds and formulations (2011-2015). Expert Opinion on Therapeutic Patents 26:11, pages 1257-1272.
Read now
Sephy Philip, Sumita Chowdhury, John R. Nelson, P. Benjamin Everett, Carolyn K. Hulme-Lowe & Jordana K. Schmier. (2016) A novel cost-effectiveness model of prescription eicosapentaenoic acid extrapolated to secondary prevention of cardiovascular diseases in the United States. Journal of Medical Economics 19:10, pages 1003-1010.
Read now
Laurence S. Sperling & John R. Nelson. (2016) History and future of omega-3 fatty acids in cardiovascular disease. Current Medical Research and Opinion 32:2, pages 301-311.
Read now
Anurag W. Kedia & Erin Lynch. (2015) Effects of switching from omega-3-acid ethyl esters to icosapent ethyl in a statin-treated patient with elevated triglycerides. Postgraduate Medicine 127:8, pages 869-873.
Read now

Articles from other publishers (48)

Heba A.S. El-Nashar, Shaden Kocaeli, Mayar Abdallah & Mohamed El-Shazly. 2023. Marine Ecosystems: A Unique Source of Valuable Bioactive Compounds. Marine Ecosystems: A Unique Source of Valuable Bioactive Compounds 355 393 .
Jessica Huston, Hannah Schaffner, Alyssa Cox, Alexander Sperry, Shelby Mcgee, Payeng Lor, Logan Langley, Blake Skrable, Majdi Ashchi, Mohannad Bisharat, Ashwini Gore, Thomas Jones, David Sutton, Mae Sheikh-Ali, Jason Berner & Rebecca Goldfaden. (2023) A Critical Review of Icosapent Ethyl in Cardiovascular Risk Reduction. American Journal of Cardiovascular Drugs 23:4, pages 393-406.
Crossref
Prince Kwaku Akowuah, Ebenezer Owusu, Esther Nutifafa Senanu & Joseph Adjei-Anang. (2023) Association between Dyslipidemia and Meibomian Gland Dysfunction: A Systematic Review and Meta-Analysis. Optometry and Vision Science 100:3, pages 211-217.
Crossref
Volker Schmiedel. (2023) Fette runter mit Omega-3?. Deutsche Heilpraktiker-Zeitschrift 18:03, pages 22-25.
Crossref
Daniel Rodriguez, Carl J. Lavie, Andrew Elagizi & Richard V. Milani. (2022) Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients 14:23, pages 5146.
Crossref
Yunjiao Yang, Wen Deng, Yanmei Wang, Tongyi Li, Yiding Chen, Cong Long, Qing Wen, Yue Wu & Qiu Chen. (2022) The effect of omega-3 fatty acids and its combination with statins on lipid profile in patients with hypertriglyceridemia: A systematic review and meta-analysis of randomized controlled trials. Frontiers in Nutrition 9.
Crossref
Gediz Dogay Us & Sohail Mushtaq. (2022) N-3 fatty acid supplementation mediates lipid profile, including small dense LDL, when combined with statins: a randomized double blind placebo controlled trial. Lipids in Health and Disease 21:1.
Crossref
Onci-Es-Saad, Oussama Lamzouri, Amine Bouchlarhem, Leila Haddar, Aabdi Mohammed, Hamza mimouni, Kaoutar zerouati, Houssam Bkiyar & Brahim Housni. (2022) A very rare case of chylomicronemia revealed by cerebral thrombophlebitis in a 4-month-old infant. Annals of Medicine and Surgery 75, pages 103276.
Crossref
Rosalia Crupi & Salvatore Cuzzocrea. (2022) Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance. Biomolecules 12:2, pages 242.
Crossref
Volker Schmiedel. (2021) Fette runter mit Omega-3? – Der Einfluss von Omega-3-Fettsäuren auf den Lipidstoffwechsel. Erfahrungsheilkunde 70:05, pages 258-263.
Crossref
Thimoteus Speer, Paul M Ridker, Arnold von Eckardstein, Stefan J Schunk & Danilo Fliser. (2021) Lipoproteins in chronic kidney disease: from bench to bedside. European Heart Journal 42:22, pages 2170-2185.
Crossref
Qingxin Cui, Ruibin Bian, Fengbo Xu, Qingshan Li, Wenhu Wang & Qiang Bian. 2021. Bioactive Natural Products. Bioactive Natural Products 371 415 .
Yessica Rodriguez-Santana & Luis Peña-Quintana. 2020. Maternal and Child Health Matters Around the World. Maternal and Child Health Matters Around the World.
Huaizhu Wu, Lu Xu & Christie M Ballantyne. (2020) Dietary and Pharmacological Fatty Acids and Cardiovascular Health. The Journal of Clinical Endocrinology & Metabolism 105:4, pages 1030-1045.
Crossref
Ann C. Skulas-Ray, Peter W.F. Wilson, William S. Harris, Eliot A. Brinton, Penny M. Kris-Etherton, Chesney K. Richter, Terry A. Jacobson, Mary B. Engler, Michael Miller, Jennifer G. Robinson, Conrad B. Blum, Delfin Rodriguez-Leyva, Sarah D. de Ferranti & Francine K. Welty. (2019) Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. Circulation 140:12.
Crossref
Quoc Tran, Thi Le, Minh Pham, Tien Do, Manh Vu, Duy Nguyen, Long Bach, Le Bui & Quoc Pham. (2019) Fatty Acid, Lipid Classes and Phospholipid Molecular Species Composition of the Marine Clam Meretrix lyrata (Sowerby 1851) from Cua Lo Beach, Nghe An Province, Vietnam. Molecules 24:5, pages 895.
Crossref
Yang Jiao, Tanya Watts, Jing Xue, Bethany Hannafon & Wei-Qun Ding. (2018) Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1. BMC Cancer 18:1.
Crossref
Charles J. Ferro, Patrick B. Mark, Mehmet Kanbay, Pantelis Sarafidis, Gunnar H. Heine, Patrick Rossignol, Ziad A. Massy, Francesca Mallamaci, Jose M. Valdivielso, Jolanta Malyszko, Marianne C. Verhaar, Robert Ekart, Raymond Vanholder, Gerard London, Alberto Ortiz & Carmine Zoccali. (2018) Lipid management in patients with chronic kidney disease. Nature Reviews Nephrology 14:12, pages 727-749.
Crossref
Youngyo Kim & Youjin Je. (2018) A modified Mediterranean diet score is inversely associated with metabolic syndrome in Korean adults. European Journal of Clinical Nutrition 72:12, pages 1682-1689.
Crossref
Francisco J. Schopfer, Dario A. Vitturi, Diane K. Jorkasky & Bruce A. Freeman. (2018) Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases. Nitric Oxide 79, pages 31-37.
Crossref
Robin K. Kuriakose & Puneet S. Braich. (2017) Dyslipidemia and its Association with Meibomian Gland Dysfunction: A Systematic Review. International Ophthalmology 38:4, pages 1809-1816.
Crossref
Jacob C Hartz, Sarah de Ferranti & Samuel Gidding. (2018) Hypertriglyceridemia in Diabetes Mellitus: Implications for Pediatric Care. Journal of the Endocrine Society 2:6, pages 497-512.
Crossref
Katya T Potkin & Steven G Potkin. (2018) New directions in therapeutics for Huntington disease. Future Neurology 13:2, pages 101-121.
Crossref
Patricia A. Rouen & Mary L. White. (2018) Dry Eye Disease. Home Healthcare Now 36:2, pages 74-83.
Crossref
Yoshinori Noda, Catarina Nilsson, Hitoshi Shimada, Hyosung Kim, Torbjörn Lundström & Toshitaka Yajima. (2018) Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of an Omega-3-Carboxylic Acid Formulation in Healthy Male Japanese Subjects: A Phase 1 Single-Blind, Randomized, Placebo-Controlled Trial. Clinical Pharmacology in Drug Development 7:2, pages 177-187.
Crossref
Christoph Baumann, Ulla Rakowski & Reiner Buchhorn. (2018) Omega-3 Fatty Acid Supplementation Improves Heart Rate Variability in Obese Children. International Journal of Pediatrics 2018, pages 1-5.
Crossref
Min Cao, Dongmei Wang, Yunxiang Mao, Fanna Kong, Guiqi Bi, Qikun Xing & Zhen Weng. (2017) Integrating transcriptomics and metabolomics to characterize the regulation of EPA biosynthesis in response to cold stress in seaweed Bangia fuscopurpurea. PLOS ONE 12:12, pages e0186986.
Crossref
Eliot A. Brinton & R. Preston Mason. (2017) Prescription omega-3 fatty acid products containing highly purified eicosapentaenoic acid (EPA). Lipids in Health and Disease 16:1.
Crossref
Megan F. Burke, Frances M. Burke & Daniel E. Soffer. (2017) Review of Cardiometabolic Effects of Prescription Omega-3 Fatty Acids. Current Atherosclerosis Reports 19:12.
Crossref
Mark L. Wells, Philippe Potin, James S. Craigie, John A. Raven, Sabeeha S. Merchant, Katherine E. Helliwell, Alison G. Smith, Mary Ellen Camire & Susan H. Brawley. (2016) Algae as nutritional and functional food sources: revisiting our understanding. Journal of Applied Phycology 29:2, pages 949-982.
Crossref
Yang Jiao, Bethany N. Hannafon, Roy R. Zhang, Kar-Ming Fung & Wei-Qun Ding. (2017) Docosahexaenoic acid and disulfiram act in concert to kill cancer cells: a mutual enhancement of their anticancer actions. Oncotarget 8:11, pages 17908-17920.
Crossref
Sung Hee Hwang, Karen Wagner, Jian Xu, Jun Yang, Xichun Li, Zhengyu Cao, Christophe Morisseau, Kin Sing Stephen Lee & Bruce D. Hammock. (2017) Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorganic & Medicinal Chemistry Letters 27:3, pages 620-625.
Crossref
Kristine Scordo & Kim Anne Pickett. (2017) CE. AJN, American Journal of Nursing 117:1, pages 24-31.
Crossref
Yixing Li, Yi Chu, Lin Yu, Huifang Kang & Lei Zhou. (2017) Transcriptomic analysis of Bama pig's liver in various nutritional states reveals a metabolic difference of fatty acids. Food Funct. 8:10, pages 3480-3490.
Crossref
Paulo Ricardo Nazário Viecili, Brenda da Silva, Gabriela E. Hirsch, Fernando G. Porto, Mariana M. Parisi, Alison R. Castanho, Michele Wender & Jonatas Z. Klafke. 2017. 1 44 .
James Backes, Deborah Anzalone, Daniel Hilleman & Julia Catini. (2016) The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia. Lipids in Health and Disease 15:1.
Crossref
Harold E. Bays, Christie M. Ballantyne, Ralph T. DoyleJr.Jr., Rebecca A. Juliano & Sephy Philip. (2016) Icosapent ethyl: Eicosapentaenoic acid concentration and triglyceride-lowering effects across clinical studies. Prostaglandins & Other Lipid Mediators 125, pages 57-64.
Crossref
James E. Talmadge. (2016) Natural product derived immune-regulatory agents. International Immunopharmacology 37, pages 5-15.
Crossref
Giulia Chiesa, Marco Busnelli, Stefano Manzini & Cinzia Parolini. (2016) Nutraceuticals and Bioactive Components from Fish for Dyslipidemia and Cardiovascular Risk Reduction. Marine Drugs 14:6, pages 113.
Crossref
Kota J Reddy & Sumita Chowdhury. (2016) Improving lipids with prescription icosapent ethyl after previous use of fish oil dietary supplements. Future Cardiology 12:3, pages 261-268.
Crossref
Richard S. Castaldo. (2016) Switching statin-treated patients from fenofibrate to the prescription omega-3 therapy icosapent ethyl: a retrospective case series. Drugs & Therapy Perspectives 32:4, pages 162-169.
Crossref
Katherine Lyseng-Williamson, Paul L. McCormack & Esther S. Kim. (2016) Icosapent ethyl in hypertriglyceridaemia: a guide to its use. Drugs & Therapy Perspectives 32:3, pages 91-97.
Crossref
Sokunthea Peou, Brittany Milliard-Hasting & Sachin A. Shah. (2016) Impact of avocado-enriched diets on plasma lipoproteins: A meta-analysis. Journal of Clinical Lipidology 10:1, pages 161-171.
Crossref
Jyothi Maria Veigas & Gabriel Fernandes. 2016. Omega-3 Fatty Acids. Omega-3 Fatty Acids 585 598 .
Karen R. Sando & Michelle Knight. (2015) Nonstatin Therapies for Management of Dyslipidemia: A Review. Clinical Therapeutics 37:10, pages 2153-2179.
Crossref
Matthew K. Ito. (2015) Long-chain omega-3 fatty acids, fibrates and niacin as therapeutic options in the treatment of hypertriglyceridemia: A review of the literature. Atherosclerosis 242:2, pages 647-656.
Crossref
Bruce P. Daggy & Francis C. Lau. 2015. Preventive Nutrition. Preventive Nutrition 823 842 .
Esther S. Kim & Paul L. McCormack. (2014) Icosapent Ethyl: A Review of Its Use in Severe Hypertriglyceridemia. American Journal of Cardiovascular Drugs 14:6, pages 471-478.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.