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Clinical Features

Autologous Platelet-Rich Plasma: A Revolution in Soft Tissue Sports Injury Management?

, MD, , MD, , MD, , PhD & , MD, MS, PhD, FRCS(Orth)
Pages 127-135 | Published online: 13 Mar 2015

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Peter Ueblacker, Lutz Haensel & Hans-Wilhelm Mueller-Wohlfahrt. (2016) Treatment of muscle injuries in football. Journal of Sports Sciences 34:24, pages 2329-2337.
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Tung-Yang YuJong-Hwei S. PangLi-Ping LinJu-Wen ChengShih-Jung LiuWen-Chung Tsai. (2021) Platelet-Rich Plasma Releasate Promotes Early Healing in Tendon After Acute Injury. Orthopaedic Journal of Sports Medicine 9:4, pages 232596712199037.
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S. I. Docking & J. Cook. (2016) Pathological tendons maintain sufficient aligned fibrillar structure on ultrasound tissue characterization (UTC). Scandinavian Journal of Medicine & Science in Sports 26:6, pages 675-683.
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J.-F. Kaux, P. Drion, J.-L. Croisier & J.-M. Crielaard. (2015) Plasma riche en plaquettes pour le traitement de lésions tendineuses. Journal de Réadaptation Médicale : Pratique et Formation en Médecine Physique et de Réadaptation 35:3, pages 181-191.
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Claudia Rizzo, Roberta Vetro, Angelo Vetro, Roberto Mantia, Angelo Iovane, Marco Di Gesù, Sonya Vasto, Laura Di Noto, Giuseppina Mazzola & Calogero Caruso. (2014) The role of platelet gel in osteoarticular injuries of young and old patients. Immunity & Ageing 11:1.
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Adam Weglein, Steve Sampson & Danielle Aufiero. 2014. Platelet-Rich Plasma. Platelet-Rich Plasma 187 201 .
B. Dallaudière, P. Meyer, V. Hummel, A. Perozziello, A. Peuchant, M.-H. Moreau-Durieux, A. Silvestre, E. Pelé, N. Wakim, P. Loriaut, P. Boyer, E. Schouman-Claeys, J.-M. Serfaty & L. Pesquer. (2013) Intérêt d’une deuxième injection rapprochée de plasma enrichi en plaquettes dans la tendinopathie en cas d’efficacité partielle de la première injection : évaluation sur un suivi de trois ans. Journal de Radiologie Diagnostique et Interventionnelle 94:9, pages 882-888.
Crossref
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Crossref
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Crossref
F. MirzatolooeiM. T. AlamdariH. R. Khalkhali. (2013) The impact of platelet-rich plasma on the prevention of tunnel widening in anterior cruciate ligament reconstruction using quadrupled autologous hamstring tendon. The Bone & Joint Journal 95-B:1, pages 65-69.
Crossref
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Crossref
Christopher K. HeeJoshua S. DinesLuis A. SolchagaVivek R. ShahJeffrey O. Hollinger. (2012) Regenerative Tendon and Ligament Healing: Opportunities with Recombinant Human Platelet-Derived Growth Factor BB-Homodimer. Tissue Engineering Part B: Reviews 18:3, pages 225-234.
Crossref
Rocco Papalia, Sebastiano Vasta, Biagio Zampogna, Andrea Tecame, Nicola Maffulli & Vincenzo Denaro. (2012) Platelet-Rich Plasma Injections and Surgery: Short-Term Outcomes and Long-Term Prognosis. Operative Techniques in Orthopaedics 22:2, pages 71-77.
Crossref
Elizaveta Kon, Giuseppe Filardo, Berardo Di Matteo, Alessandro Di Martino & Maurilio Marcacci. (2012) Platelet-Rich Plasma in Sports Medicine: New Treatment for Tendon and Cartilage Lesions. Operative Techniques in Orthopaedics 22:2, pages 78-85.
Crossref
Omer Mei-Dan & Michael R. Carmont. (2012) Novel Applications of Platelet-Rich Plasma Technology in Musculoskeletal Medicine and Surgery. Operative Techniques in Orthopaedics 22:2, pages 56-63.
Crossref
Andre F. Steinert, Kellie K. Middleton, Paulo H. Araujo & Freddie H. Fu. (2012) Platelet-Rich Plasma in Orthopaedic Surgery and Sports Medicine: Pearls, Pitfalls, and New Trends in Research. Operative Techniques in Orthopaedics 22:2, pages 91-103.
Crossref
F. Smets, J.-L. Croisier, B. Forthomme, J.-M. Crielaard & J.-F. Kaux. (2012) Applications cliniques du plasma riche en plaquettes (PRP) dans les lésions tendineuses : revue de la littérature. Science & Sports 27:3, pages 141-153.
Crossref
Eduardo Anitua, Roberto Prado, Mikel Sánchez & Gorka Orive. (2012) Platelet-Rich Plasma: Preparation and Formulation. Operative Techniques in Orthopaedics 22:1, pages 25-32.
Crossref
Giuliana Gobbi & Marco Vitale. (2012) Platelet-Rich Plasma Preparations for Biological Therapy: Applications and Limits. Operative Techniques in Orthopaedics 22:1, pages 10-15.
Crossref
S Jassim & FS Haddad. (2012) Platelet-rich plasma in sports medicine: hot favourite or non-starter?. British Journal of Hospital Medicine 73:2, pages 91-94.
Crossref
Hatim Thaker & Arun K. Sharma. (2012) Engaging Stem Cells for Customized Tendon Regeneration. Stem Cells International 2012, pages 1-12.
Crossref
Francesco Oliva, Alessio Giai Via & Nicola Maffulli. (2011) Role of Growth Factors in Rotator Cuff Healing. Sports Medicine and Arthroscopy Review 19:3, pages 218-226.
Crossref
David M. DeChellis & Megan Helen Cortazzo. (2011) Regenerative medicine in the field of pain medicine: Prolotherapy, platelet-rich plasma therapy, and stem cell therapy—Theory and evidence. Techniques in Regional Anesthesia and Pain Management 15:2, pages 74-80.
Crossref
A. Del Buono, R. Papalia, V. Denaro, G. Maccauro & N. Maffulli. (2011) Platelet Rich Plasma and Tendinopathy: State of the Art. International Journal of Immunopathology and Pharmacology 24:1_suppl2, pages 79-83.
Crossref

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