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Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

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Pages 674-683 | Published online: 23 Jan 2013

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Salvatore Nesci, Alessandra Pagliarani, Cristina Algieri & Fabiana Trombetti. (2020) Mitochondrial F-type ATP synthase: multiple enzyme functions revealed by the membrane-embedded FO structure. Critical Reviews in Biochemistry and Molecular Biology 55:4, pages 309-321.
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Saverio Marchi, Veronica Angela Maria Vitto, Simone Patergnani & Paolo Pinton. (2019) High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP). Cell Cycle 18:8, pages 914-916.
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Carlotta Giorgi, Massimo Bonora & Paolo Pinton. (2015) Inside the tumor: p53 modulates calcium homeostasis. Cell Cycle 14:7, pages 933-934.
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Massimo Bonora, José Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi & Paolo Pinton. (2014) Novel insights into the mitochondrial permeability transition. Cell Cycle 13:17, pages 2666-2670.
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Saverio Marchi, Carlotta Giorgi, Monika Oparka, Jerzy Duszynski, Mariusz R Wieckowski & Paolo Pinton. (2014) Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes. Molecular & Cellular Oncology 1:2.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Ibrahim Damilare Boyenle, Abdulquddus Kehinde Oyedele, Abdeen Tunde Ogunlana, Aishat Folashade Adeyemo, Faith Sunday Oyelere, Olateju Balikis Akinola, Temitope Isaac Adelusi, Leonard Ona Ehigie & Adeola Folasade Ehigie. (2022) Targeting the mitochondrial permeability transition pore for drug discovery: Challenges and opportunities. Mitochondrion 63, pages 57-71.
Crossref
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Crossref
Carlos M. Palmeira, Ivo F. Machado & João Ramalho-Santos. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 1103 1116 .
Samaneh H. Shabani & Azam Bolhassani. 2022. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 517 534 .
Alain Tenenbaum, Andreas Katsambas, Ariel Luksenburg, Athanasios Pavlidis, Daniel de Rossi Fattaccioli, Ercin Ozüntürk, Hana Zelenkova, Juan J. Barcia, Junfeng Du, Khaled Al-Nuaimi, Laura Atzori, Maurizio Ceccarelli, Mauro Tiziani, Róbert Késmárszky, Saad AlSogair & Sergio Noviello. 2022. Atlas of Dermatology, Dermatopathology and Venereology. Atlas of Dermatology, Dermatopathology and Venereology 599 656 .
Maria A. Neginskaya & Evgeny V. Pavlov. 2022. Inorganic Polyphosphates. Inorganic Polyphosphates 15 26 .
Sandeep P. Dumbali & Pamela L. Wenzel. 2023. Cell Biology and Translational Medicine, Volume 18. Cell Biology and Translational Medicine, Volume 18 1 22 .
Pooja Patel, Arielys Mendoza, Dexter J. Robichaux, Meng C. Wang, Xander H. T. Wehrens & Jason Karch. (2021) Inhibition of the Anti-Apoptotic Bcl-2 Family by BH3 Mimetics Sensitize the Mitochondrial Permeability Transition Pore Through Bax and Bak. Frontiers in Cell and Developmental Biology 9.
Crossref
Giampaolo Morciano, Natalia Naumova, Piotr Koprowski, Sara Valente, Vilma A. Sardão, Yaiza Potes, Alessandro Rimessi, Mariusz R. Wieckowski & Paulo J. Oliveira. (2021) The mitochondrial permeability transition pore: an evolving concept critical for cell life and death. Biological Reviews 96:6, pages 2489-2521.
Crossref
Yanguo Xin, Xiaodong Zhang, Jingye Li, Hui Gao, Jiayu Li, Junli Li, Wenyu Hu & Hongwei Li. (2021) New Insights Into the Role of Mitochondria Quality Control in Ischemic Heart Disease. Frontiers in Cardiovascular Medicine 8.
Crossref
Vanessa Checchetto, Luigi Leanza, Diego De Stefani, Rosario Rizzuto, Erich Gulbins & Ildiko Szabo. (2021) Mitochondrial K+ channels and their implications for disease mechanisms. Pharmacology & Therapeutics 227, pages 107874.
Crossref
Wylly Ramsés García-Niño, Cecilia Zazueta, Mabel Buelna-Chontal & Alejandro Silva-Palacios. (2021) Mitochondrial Quality Control in Cardiac-Conditioning Strategies against Ischemia-Reperfusion Injury. Life 11:11, pages 1123.
Crossref
Giuseppe Federico Amodeo, Natalya Krilyuk & Evgeny V. Pavlov. (2021) Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D. International Journal of Molecular Sciences 22:20, pages 11022.
Crossref
Suzanne Angeli, Anna Foulger, Manish Chamoli, Tanuja Harshani Peiris, Akos Gerencser, Azar Asadi Shahmirzadi, Julie Andersen & Gordon Lithgow. (2021) The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging. eLife 10.
Crossref
Sung-Hyun Hwang, Yeseul Yang, Jae-Ha Jung & Yongbaek Kim. (2021) Heterogeneous response of cancer-associated fibroblasts to the glucose deprivation through mitochondrial calcium uniporter. Experimental Cell Research 406:2, pages 112778.
Crossref
Andrea Carrer, Ludovica Tommasin, Justina Šileikytė, Francesco Ciscato, Riccardo Filadi, Andrea Urbani, Michael Forte, Andrea Rasola, Ildikò Szabò, Michela Carraro & Paolo Bernardi. (2021) Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase. Nature Communications 12:1.
Crossref
Paulina Patalas-Krawczyk, Dominika Malinska, Jaroslaw Walczak, Gilles Kratzer, Monika Prill, Bernadeta Michalska, Karolina Drabik, Bjorn Titz, Yvan Eb-Levadoux, Thomas Schneider, Jedrzej Szymanski, Julia Hoeng, Manuel C. Peitsch, Jerzy Duszynski, Joanna Szczepanowska, Marco Van der Toorn, Carole Mathis & Mariusz R. Wieckowski. (2021) Effects of plant alkaloids on mitochondrial bioenergetic parameters. Food and Chemical Toxicology 154, pages 112316.
Crossref
Salvatore Nesci & Speranza Rubattu. (2021) The ATP synthase glycine zipper of the c subunits: From the structural to the functional role in mitochondrial biology of cardiovascular diseases. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:9, pages 119075.
Crossref
Olga Krestinina, Yulia Baburina & Roman Krestinin. (2021) Mitochondrion as a Target of Astaxanthin Therapy in Heart Failure. International Journal of Molecular Sciences 22:15, pages 7964.
Crossref
Alberto Danese, Sara Leo, Alessandro Rimessi, Mariusz R. Wieckowski, Francesco Fiorica, Carlotta Giorgi & Paolo Pinton. (2021) Cell death as a result of calcium signaling modulation: A cancer-centric prospective. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:8, pages 119061.
Crossref
Ishnoor Kaur, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Lotfi Aleya & Simona Bungau. (2021) Connecting the dots between mitochondrial dysfunction and Parkinson’s disorder: focus mitochondria-targeting therapeutic paradigm in mitigating the disease severity. Environmental Science and Pollution Research 28:28, pages 37060-37081.
Crossref
Mille Vissing, John Ploen, Mascha Pervan, Kitt Vestergaard, Mazen Schnefeldt, Stine Krog Frandsen, Søren Rafael Rafaelsen, Christina Louise Lindhardt, Lars Henrik Jensen, Achim Rody & Julie Gehl. (2021) Study protocol designed to investigate tumour response to calcium electroporation in cancers affecting the skin: a non-randomised phase II clinical trial. BMJ Open 11:6, pages e046779.
Crossref
Faustino Mollinedo & Consuelo Gajate. (2021) Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine. Pharmaceutics 13:5, pages 763.
Crossref
Lea K. Seidlmayer, Benjamin J. Hanson, Phung N. Thai, Saul Schaefer, Donald M. Bers & Elena N. Dedkova. (2021) PK11195 Protects From Cell Death Only When Applied During Reperfusion: Succinate-Mediated Mechanism of Action. Frontiers in Physiology 12.
Crossref
Salvatore Nesci & Alessandra Pagliarani. (2021) Ca 2+ as cofactor of the mitochondrial H + ‐translocating F 1 F O ‐ATP (hydrol)ase . Proteins: Structure, Function, and Bioinformatics 89:5, pages 477-482.
Crossref
Giuseppe Federico Amodeo, Brenda Yasie Lee, Natalya Krilyuk, Carina Teresa Filice, Denis Valyuk, Daniel Erik Otzen, Sergey Noskov, Zoya Leonenko & Evgeny V. Pavlov. (2021) C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition. Scientific Reports 11:1.
Crossref
Yulia Baburina, Alexey Lomovsky & Olga Krestinina. (2021) Melatonin as a Potential Multitherapeutic Agent. Journal of Personalized Medicine 11:4, pages 274.
Crossref
Fei Deng, Xiaoping Zheng, Isha Sharma, Yingbo Dai, Yinhuai Wang & Yashpal S. Kanwar. (2021) Regulated cell death in cisplatin-induced AKI: relevance of myo -inositol metabolism . American Journal of Physiology-Renal Physiology 320:4, pages F578-F595.
Crossref
Giampaolo Morciano, Gaia Pedriali, Massimo Bonora, Rita Pavasini, Elisa Mikus, Simone Calvi, Matteo Bovolenta, Magdalena Lebiedzinska-Arciszewska, Mirko Pinotti, Alberto Albertini, Mariusz R. Wieckowski, Carlotta Giorgi, Roberto Ferrari, Lorenzo Galluzzi, Gianluca Campo & Paolo Pinton. (2021) A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients. Cell Reports 35:2, pages 108983.
Crossref
Aleksandra Kaliszewska, Joseph Allison, Matteo Martini & Natalia Arias. (2021) The Interaction of Diet and Mitochondrial Dysfunction in Aging and Cognition. International Journal of Molecular Sciences 22:7, pages 3574.
Crossref
Jana Královičová, Ivana Borovská, Reuben Pengelly, Eunice Lee, Pavel Abaffy, Radek Šindelka, Frank Grutzner & Igor Vořechovský. (2021) Restriction of an intron size en route to endothermy . Nucleic Acids Research 49:5, pages 2460-2487.
Crossref
Salvatore Nesci, Fabiana Trombetti, Alessandra Pagliarani, Vittoria Ventrella, Cristina Algieri, Gaia Tioli & Giorgio Lenaz. (2021) Molecular and Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System: Implications for Pathology. Life 11:3, pages 242.
Crossref
Matthias Kist & Domagoj Vucic. (2021) Cell death pathways: intricate connections and disease implications. The EMBO Journal 40:5.
Crossref
Martijn Kerkhofs, Rita La Rovere, Kirsten Welkenhuysen, Ann Janssens, Peter Vandenberghe, Muniswamy Madesh, Jan B. Parys & Geert Bultynck. (2021) BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening. Cell Calcium 94, pages 102333.
Crossref
Giuseppe F. Amodeo & Evgeny V. Pavlov. (2021) Amyloid β, α-synuclein and the c subunit of the ATP synthase: Can these peptides reveal an amyloidogenic pathway of the permeability transition pore?. Biochimica et Biophysica Acta (BBA) - Biomembranes 1863:3, pages 183531.
Crossref
Andrew C. Kent, Khairat Bahgat Youssef El Baradie & Mark W. Hamrick. (2021) Targeting the Mitochondrial Permeability Transition Pore to Prevent Age-Associated Cell Damage and Neurodegeneration. Oxidative Medicine and Cellular Longevity 2021, pages 1-15.
Crossref
Masami Koushi & Rei Asakai. (2021) Bisindolylpyrrole Induces a Cpr3- and Porin1/2-Dependent Transition in Yeast Mitochondrial Permeability in a Low Conductance State via the AACs-Associated Pore. International Journal of Molecular Sciences 22:3, pages 1212.
Crossref
Jasiel O. Strubbe-Rivera, Jason R. Schrad, Evgeny V. Pavlov, James F. Conway, Kristin N. Parent & Jason N. Bazil. (2021) The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function. Scientific Reports 11:1.
Crossref
Daniela Ramaccini, Vanessa Montoya-Uribe, Femke J. Aan, Lorenzo Modesti, Yaiza Potes, Mariusz R. Wieckowski, Irena Krga, Marija Glibetić, Paolo Pinton, Carlotta Giorgi & Michelle L. Matter. (2021) Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy. Frontiers in Cell and Developmental Biology 8.
Crossref
Elisa Canepa & Silvia Fossati. (2021) Impact of Tau on Neurovascular Pathology in Alzheimer's Disease. Frontiers in Neurology 11.
Crossref
Cristina Algieri, Salvatore Nesci, Fabiana Trombetti, Micaela Fabbri, Vittoria Ventrella & Alessandra Pagliarani. (2021) Mitochondrial F1FO-ATPase and permeability transition pore response to sulfide in the midgut gland of Mytilus galloprovincialis. Biochimie 180, pages 222-228.
Crossref
H. Alves-Figueiredo, C. Silva-Platas, O. Lozano, E. Vázquez-Garza, C.E. Guerrero-Beltrán, A. Zarain-Herzberg & G. García-Rivas. (2021) A systematic review of post-translational modifications in the mitochondrial permeability transition pore complex associated with cardiac diseases. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:1, pages 165992.
Crossref
Roberto Docampo, Anibal E. Vercesi, Guozhong Huang, Noelia Lander, Miguel A. Chiurillo & Mayara Bertolini. 2021. Inter-Organellar Ca2+ Signaling in Health and Disease - Part A. Inter-Organellar Ca2+ Signaling in Health and Disease - Part A 261 289 .
Michela Carraro & Paolo Bernardi. 2021. Encyclopedia of Biological Chemistry III. Encyclopedia of Biological Chemistry III 997 1007 .
Yuting Cui, Mingyue Pan, Jing Ma, Xinhua Song, Weiling Cao & Peng Zhang. (2020) Recent progress in the use of mitochondrial membrane permeability transition pore in mitochondrial dysfunction-related disease therapies. Molecular and Cellular Biochemistry 476:1, pages 493-506.
Crossref
Samaneh H. Shabani & Azam Bolhassani. 2020. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 1 18 .
Edmundo Chávez, Mabel Buelna-Chontal, Arturo Macías-López, Luz Hernández-Esquivel, Francisco Correa & Natalia Pavón. (2020) Interaction of Agaric Acid with the Adenine Nucleotide Translocase Induces Mitochondrial Oxidative Stress. Biochemistry Research International 2020, pages 1-8.
Crossref
Hyunsu Jung, Su Yeon Kim, Fatma Sema Canbakis Cecen, Yongcheol Cho & Seok-Kyu Kwon. (2020) Dysfunction of Mitochondrial Ca2+ Regulatory Machineries in Brain Aging and Neurodegenerative Diseases. Frontiers in Cell and Developmental Biology 8.
Crossref
Nickolay Brustovetsky. (2020) The Role of Adenine Nucleotide Translocase in the Mitochondrial Permeability Transition. Cells 9:12, pages 2686.
Crossref
Ilaria Genovese, Bianca Vezzani, Alberto Danese, Lorenzo Modesti, Veronica Angela Maria Vitto, Virginia Corazzi, Stefano Pelucchi, Paolo Pinton & Carlotta Giorgi. (2020) Mitochondria as the decision makers for cancer cell fate: from signaling pathways to therapeutic strategies. Cell Calcium 92, pages 102308.
Crossref
Manuel Gutiérrez-Aguilar. (2020) Mitochondrial calcium transport and permeability transition as rational targets for plant protection. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1861:12, pages 148288.
Crossref
Rodrigo A. Quntanilla & Carola Tapia-Monsalves. (2020) The Role of Mitochondrial Impairment in Alzheimer´s Disease Neurodegeneration: The Tau Connection. Current Neuropharmacology 18:11, pages 1076-1091.
Crossref
Jasmine A. Nirody, Itay Budin & Padmini Rangamani. (2020) ATP synthase: Evolution, energetics, and membrane interactions. Journal of General Physiology 152:11.
Crossref
Yingying Guo, Kailiang Zhang, Xu Gao, Zhou Zhou, Zhiheng Liu, Kevin Yang, Kai Huang, Qinglin YangQinqiang Long. (2020) Sustained Oligomycin Sensitivity Conferring Protein Expression in Cardiomyocytes Protects Against Cardiac hypertrophy Induced by Pressure Overload via Improving Mitochondrial Function. Human Gene Therapy 31:21-22, pages 1178-1189.
Crossref
Gergely Pinke, Long Zhou & Leonid A. Sazanov. (2020) Cryo-EM structure of the entire mammalian F-type ATP synthase. Nature Structural & Molecular Biology 27:11, pages 1077-1085.
Crossref
Umberto Lucia, Giulia Grisolia & Thomas S. Deisboeck. (2020) Alzheimer’s Disease: A Thermodynamic Perspective. Applied Sciences 10:21, pages 7562.
Crossref
Natalia Naumova & Radek Šachl. (2020) Regulation of Cell Death by Mitochondrial Transport Systems of Calcium and Bcl-2 Proteins. Membranes 10:10, pages 299.
Crossref
Umberto Lucia & Giulia Grisolia. (2020) Seebeck–Peltier Transition Approach to Oncogenesis. Applied Sciences 10:20, pages 7166.
Crossref
Masami Koushi, Yasunori Aoyama, Yoshiko Kamei & Rei Asakai. (2020) Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC1/2 and cyclophilin D-dependent manner via the ANT-associated pore. Scientific Reports 10:1.
Crossref
Nelli Mnatsakanyan & Elizabeth Ann Jonas. (2020) The new role of F1Fo ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection. Experimental Neurology 332, pages 113400.
Crossref
Ines C.M. Simoes, Giampaolo Morciano, Magdalena Lebiedzinska-Arciszewska, Gianluca Aguiari, Paolo Pinton, Yaiza Potes & Mariusz R. Wieckowski. (2020) The mystery of mitochondria-ER contact sites in physiology and pathology: A cancer perspective. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866:10, pages 165834.
Crossref
Umberto Lucia & Giulia Grisolia. (2020) Non-Equilibrium Thermodynamic Approach to Ca2+-Fluxes in Cancer. Applied Sciences 10:19, pages 6737.
Crossref
Tobias E. Spikes, Martin G. Montgomery & John E. Walker. (2020) Structure of the dimeric ATP synthase from bovine mitochondria. Proceedings of the National Academy of Sciences 117:38, pages 23519-23526.
Crossref
Michela Carraro, Kristen Jones, Geppo Sartori, Marco Schiavone, Salvatore Antonucci, Roza Kucharczyk, Jean-Paul di Rago, Cinzia Franchin, Giorgio Arrigoni, Michael Forte & Paolo Bernardi. (2020) The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore. Cell Reports 32:9, pages 108095.
Crossref
Pawel Licznerski, Han-A Park, Harshvardhan Rolyan, Rongmin Chen, Nelli Mnatsakanyan, Paige Miranda, Morven Graham, Jing Wu, Nicole Cruz-Reyes, Nikita Mehta, Sana Sohail, Jorge Salcedo, Erin Song, Charles Effman, Samuel Effman, Lucas Brandao, Gulan N. Xu, Amber Braker, Valentin K. Gribkoff, Richard J. Levy & Elizabeth A. Jonas. (2020) ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome. Cell 182:5, pages 1170-1185.e9.
Crossref
Stephen Hurst, Fabrice Gonnot, Maya Dia, Claire Crola Da Silva, Ludovic Gomez & Shey-Shing Sheu. (2020) Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion. Cell Death & Disease 11:8.
Crossref
Jian‐fei Yan, Wen‐pin Qin, Bo‐cheng Xiao, Qian‐qian Wan, Franklin R. TayLi‐na Niu & Kai Jiao. (2020) Pathological calcification in osteoarthritis: an outcome or a disease initiator?. Biological Reviews 95:4, pages 960-985.
Crossref
Han-A Park & Amy C. Ellis. (2020) Dietary Antioxidants and Parkinson’s Disease. Antioxidants 9:7, pages 570.
Crossref
Michela Carraro, Andrea Carrer, Andrea Urbani & Paolo Bernardi. (2020) Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection. Journal of Molecular and Cellular Cardiology 144, pages 76-86.
Crossref
Nelli Mnatsakanyan & Elizabeth Ann Jonas. (2020) ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration. Journal of Molecular and Cellular Cardiology 144, pages 109-118.
Crossref
Raymond J. Winquist & Valentin K. Gribkoff. (2020) Targeting putative components of the mitochondrial permeability transition pore for novel therapeutics. Biochemical Pharmacology 177, pages 113995.
Crossref
Alejandro Silva-Palacios, Cecilia Zazueta & José Pedraza-Chaverri. (2020) ER membranes associated with mitochondria: Possible therapeutic targets in heart-associated diseases. Pharmacological Research 156, pages 104758.
Crossref
Jiyao Zhang, Luwen Zhu, Hongyu Li & Qiang Tang. (2020) Electroacupuncture Pretreatment as a Novel Avenue to Protect Heart against Ischemia and Reperfusion Injury. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-9.
Crossref
Guozhong Huang & Roberto Docampo. (2020) The Mitochondrial Calcium Uniporter Interacts with Subunit c of the ATP Synthase of Trypanosomes and Humans. mBio 11:2.
Crossref
Devasena Ponnalagu & Harpreet Singh. (2020) Insights Into the Role of Mitochondrial Ion Channels in Inflammatory Response. Frontiers in Physiology 11.
Crossref
Wing-Kee Lee & Frank Thévenod. (2020) Cell organelles as targets of mammalian cadmium toxicity. Archives of Toxicology 94:4, pages 1017-1049.
Crossref
Cristina Algieri, Fabiana Trombetti, Alessandra Pagliarani, Vittoria Ventrella & Salvatore Nesci. (2020) Phenylglyoxal inhibition of the mitochondrial F1FO-ATPase activated by Mg2+ or by Ca2+ provides clues on the mitochondrial permeability transition pore. Archives of Biochemistry and Biophysics 681, pages 108258.
Crossref
Salvatore Nesci. (2020) The mitochondrial permeability transition pore in cell death: A promising drug binding bioarchitecture. Medicinal Research Reviews 40:2, pages 811-817.
Crossref
Michela Carraro & Paolo Bernardi. 2020. Mitochondria, 3rd Edition. Mitochondria, 3rd Edition 369 379 .
Nicolas Rosa, Flore Sneyers, Jan B. Parys & Geert Bultynck. 2020. Cell Death Regulation in Health and Disease - Part A. Cell Death Regulation in Health and Disease - Part A 101 148 .
Pooja Patel & Jason Karch. 2020. Cell Death Regulation In Health And Disease - Part C. Cell Death Regulation In Health And Disease - Part C 153 209 .
Lorenzo Galluzzi, Andreas Linkermann, Oliver Kepp & Guido Kroemer. 2020. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 74 83.e4 .
Alain Tenenbaum, Andreas Katsambas, Ariel Luksenburg, Athanasios Pavlidis, Daniel de Rossi Fattaccioli, Ercin Ozüntürk, Hana Zelenkova, Juan J. Barcia, Junfeng Du, Khaled Al-Nuaimi, Laura Atzori, Maurizio Ceccarelli, Mauro Tiziani, Róbert Késmárszky, Saad AlSogair & Sergio Noviello. 2020. Atlas of Dermatology, Dermatopathology and Venereology. Atlas of Dermatology, Dermatopathology and Venereology 1 58 .
Zdenek Drahota, Marketa Hlavackova & Bohuslav Ostadal. 2020. Sex Differences in Heart Disease. Sex Differences in Heart Disease 257 265 .
Nelli Mnatsakanyan, Marc C. Llaguno, Youshan Yang, Yangyang Yan, Joachim Weber, Fred J. Sigworth & Elizabeth A. Jonas. (2019) A mitochondrial megachannel resides in monomeric F1FO ATP synthase. Nature Communications 10:1.
Crossref
Cristina Algieri, Fabiana Trombetti, Alessandra Pagliarani, Vittoria Ventrella, Chiara Bernardini, Micaela Fabbri, Monica Forni & Salvatore Nesci. (2019) Mitochondrial Ca 2+ ‐activated F 1 F O ‐ATPase hydrolyzes ATP and promotes the permeability transition pore . Annals of the New York Academy of Sciences 1457:1, pages 142-157.
Crossref
Natalia V. Naryzhnaya, Leonid N. Maslov & Peter R. Oeltgen. (2019) Pharmacology of mitochondrial permeability transition pore inhibitors. Drug Development Research 80:8, pages 1013-1030.
Crossref
Yulia Baburina, Roman Krestinin, Irina Odinokova, Linda Sotnikova, Alexey Kruglov & Olga Krestinina. (2019) Astaxanthin Inhibits Mitochondrial Permeability Transition Pore Opening in Rat Heart Mitochondria. Antioxidants 8:12, pages 576.
Crossref
M. V. Dubinin, V. N. Samartsev, A. E. Stepanova, A. A. Semenova, E. I. Khoroshavina & K. N. Belosludtsev. (2020) A Comparative Study of the Effects of Palmitic Acid and ω-Hydroxypalmitic Acid as Inducers of Ca2+-Dependent Permeabilization of Liver Mitochondria and Lecithin Liposomes. Biophysics 64:6, pages 908-916.
Crossref
Luigi Leanza, Vanessa Checchetto, Lucia Biasutto, Andrea Rossa, Roberto Costa, Magdalena Bachmann, Mario Zoratti & Ildiko Szabo. (2019) Pharmacological modulation of mitochondrial ion channels. British Journal of Pharmacology 176:22, pages 4258-4283.
Crossref
Salvatore Nesci, Fabiana Trombetti, Cristina Algieri & Alessandra Pagliarani. (2019) A Therapeutic Role for the F1FO-ATP Synthase. SLAS Discovery 24:9, pages 893-903.
Crossref
Dominic P. Del ReDulguun Amgalan, Andreas LinkermannQinghang LiuRichard N. Kitsis. (2019) Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease. Physiological Reviews 99:4, pages 1765-1817.
Crossref
Benjamin Wacquier, Laurent Combettes & Geneviève Dupont. (2019) Cytoplasmic and Mitochondrial Calcium Signaling: A Two-Way Relationship. Cold Spring Harbor Perspectives in Biology 11:10, pages a035139.
Crossref
Iraj Yazdani, Raheleh Majdani, Morteza Ghasemnejad-berenji & Ahmad Reza Dehpour. (2019) Comparison of multiple doses of cyclosporine A on germ cell apoptosis and epididymal sperm parameters after testicular ischemia/reperfusion in rats. Experimental and Molecular Pathology 110, pages 104271.
Crossref
N. V. Naryzhnaya, L. N. Maslov, Yu. B. Lishmanov, E. A. Nesterov, A. S. Yaggi & M. S. Suleiman. (2019) The Mitochondrial Permeability Transition Pore – a Regulator of the Resistance of the Heart to Reperfusion. Neuroscience and Behavioral Physiology 49:8, pages 943-953.
Crossref
Andrea Urbani, Valentina Giorgio, Andrea Carrer, Cinzia Franchin, Giorgio Arrigoni, Chimari Jiko, Kazuhiro Abe, Shintaro Maeda, Kyoko Shinzawa-Itoh, Janna F. M. Bogers, Duncan G. G. McMillan, Christoph Gerle, Ildikò Szabò & Paolo Bernardi. (2019) Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore. Nature Communications 10:1.
Crossref
B. OstadalZ. DrahotaJ. HoustekM. MilerovaI. OstadalovaM. HlavackovaF. Kolar. (2019) Developmental and sex differences in cardiac tolerance to ischemia–reperfusion injury: the role of mitochondria. Canadian Journal of Physiology and Pharmacology 97:9, pages 808-814.
Crossref
Jason Karch, Michael J. Bround, Hadi KhalilMichelle A. SargentNadina Latchman, Naohiro TeradaPablo M. Peixoto & Jeffery D. Molkentin. (2019) Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Science Advances 5:8.
Crossref
Michela Carraro, Vanessa Checchetto, Ildikó Szabó & Paolo Bernardi. (2019) F‐ ATP synthase and the permeability transition pore: fewer doubts, more certainties . FEBS Letters 593:13, pages 1542-1553.
Crossref
Joe Carroll, Jiuya He, Shujing Ding, Ian M. Fearnley & John E. Walker. (2019) Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase. Proceedings of the National Academy of Sciences 116:26, pages 12816-12821.
Crossref
Rongmin Chen, Han-A Park, Nelli Mnatsakanyan, Yulong Niu, Pawel Licznerski, Jing Wu, Paige Miranda, Morven Graham, Jack Tang, Agnita J. W. Boon, Giovanni Cossu, Wim Mandemakers, Vincenzo Bonifati, Peter J. S. Smith, Kambiz N. Alavian & Elizabeth A. Jonas. (2019) Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth. Cell Death & Disease 10:6.
Crossref
K. N. Belosludtsev, M. V. Dubinin, N. V. Belosludtseva & G. D. Mironova. (2019) Mitochondrial Ca2+ Transport: Mechanisms, Molecular Structures, and Role in Cells. Biochemistry (Moscow) 84:6, pages 593-607.
Crossref
Roberta Peruzzo & Ildiko Szabo. (2019) Contribution of Mitochondrial Ion Channels to Chemo-Resistance in Cancer Cells. Cancers 11:6, pages 761.
Crossref
Justina Šileikytė & Michael Forte. (2019) The Mitochondrial Permeability Transition in Mitochondrial Disorders. Oxidative Medicine and Cellular Longevity 2019, pages 1-11.
Crossref
Anna Tarocco, Natascia Caroccia, Giampaolo Morciano, Mariusz R. Wieckowski, Gina Ancora, Giampaolo Garani & Paolo Pinton. (2019) Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care. Cell Death & Disease 10:4.
Crossref
Lea K. Seidlmayer, Maria R. Gomez-Garcia, Toshikazu Shiba, George A. PorterJr.Jr., Evgeny V. Pavlov, Donald M. Bers & Elena N. Dedkova. (2019) Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation. Archives of Biochemistry and Biophysics 662, pages 177-189.
Crossref
Qi-Tong Lin & Peter Stathopulos. (2019) Molecular Mechanisms of Leucine Zipper EF-Hand Containing Transmembrane Protein-1 Function in Health and Disease. International Journal of Molecular Sciences 20:2, pages 286.
Crossref
M. V. Dubinin, V. N. Samartsev, V. S. Starinets, E. I. Khoroshavina & K. N. Belosludtsev. (2019) Induction of the Ca2+-Dependent Permeability Transition in Liver Mitochondria by α,ω-Hexadecanedioic Acid is Blocked by Inorganic Phosphate in the Presence of Cyclosporin A. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 13:1, pages 58-66.
Crossref
Massimo Bonora, Mariusz R. Wieckowski, David A. Sinclair, Guido Kroemer, Paolo Pinton & Lorenzo Galluzzi. (2018) Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles. Nature Reviews Cardiology 16:1, pages 33-55.
Crossref
Maria A. Neginskaya, Maria E. Solesio, Elena V. Berezhnaya, Giuseppe F. Amodeo, Nelli Mnatsakanyan, Elizabeth A. Jonas & Evgeny V. Pavlov. (2019) ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore. Cell Reports 26:1, pages 11-17.e2.
Crossref
Wulf Tonnus & Andreas Linkermann. 2019. Clinical Immunology. Clinical Immunology 197 205.e1 .
Pasquale Pagliaro, Saveria Femminò & Claudia Penna. 2019. Oxidative Stress in Heart Diseases. Oxidative Stress in Heart Diseases 289 324 .
George A. PorterJr.Jr. & Gisela Beutner. (2018) Cyclophilin D, Somehow a Master Regulator of Mitochondrial Function. Biomolecules 8:4, pages 176.
Crossref
Anibal E. Vercesi, Roger F. Castilho, Alicia J. Kowaltowski, Helena C.F. de Oliveira, Nadja C. de Souza-Pinto, Tiago R. Figueira & Estela N.B. Busanello. (2018) Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition. Free Radical Biology and Medicine 129, pages 1-24.
Crossref
Komal Kalani, Shi Fang Yan & Shirley ShiDu Yan. (2018) Mitochondrial permeability transition pore: a potential drug target for neurodegeneration. Drug Discovery Today 23:12, pages 1983-1989.
Crossref
Yoshiko Kamei, Masami Koushi, Yasunori Aoyama & Rei Asakai. (2018) The yeast mitochondrial permeability transition is regulated by reactive oxygen species, endogenous Ca2+ and Cpr3, mediating cell death. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1859:12, pages 1313-1326.
Crossref
Valentina De Col, Elisa Petrussa, Valentino Casolo, Enrico Braidot, Giovanna Lippe, Antonio Filippi, Carlo Peresson, Sonia Patui, Alberto Bertolini, Valentina Giorgio, Vanessa Checchetto, Angelo Vianello, Paolo Bernardi & Marco Zancani. (2018) Properties of the Permeability Transition of Pea Stem Mitochondria. Frontiers in Physiology 9.
Crossref
Alice Biosa, Irene Arduini, Maria Eugenia Soriano, Valentina Giorgio, Paolo Bernardi, Marco Bisaglia & Luigi Bubacco. (2018) Dopamine Oxidation Products as Mitochondrial Endotoxins, a Potential Molecular Mechanism for Preferential Neurodegeneration in Parkinson’s Disease. ACS Chemical Neuroscience 9:11, pages 2849-2858.
Crossref
Paolo Bernardi. (2018) Why F-ATP Synthase Remains a Strong Candidate as the Mitochondrial Permeability Transition Pore. Frontiers in Physiology 9.
Crossref
Giuseppe Paradies, Valeria Paradies, Francesca Maria Ruggiero & Giuseppe Petrosillo. (2018) Mitochondrial bioenergetics and cardiolipin alterations in myocardial ischemia-reperfusion injury: implications for pharmacological cardioprotection. American Journal of Physiology-Heart and Circulatory Physiology 315:5, pages H1341-H1352.
Crossref
Pascal Röderer, Lara Klatt, Felix John, Verena Theis, Konstanze F. Winklhofer, Carsten Theiss & Veronika Matschke. (2018) Increased ROS Level in Spinal Cord of Wobbler Mice due to Nmnat2 Downregulation. Molecular Neurobiology 55:11, pages 8414-8424.
Crossref
Ana García-Aguilar & José M. Cuezva. (2018) A Review of the Inhibition of the Mitochondrial ATP Synthase by IF1 in vivo: Reprogramming Energy Metabolism and Inducing Mitohormesis. Frontiers in Physiology 9.
Crossref
Lishu Guo, Michela Carraro, Geppo Sartori, Giovanni Minervini, Ove Eriksson, Valeria Petronilli & Paolo Bernardi. (2018) Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal. Journal of Biological Chemistry 293:38, pages 14632-14645.
Crossref
Salvatore Nesci, Fabiana Trombetti, Vittoria Ventrella & Alessandra Pagliarani. (2018) From the Ca 2+ -activated F 1 F O -ATPase to the mitochondrial permeability transition pore: an overview. Biochimie 152, pages 85-93.
Crossref
Giampaolo Morciano, Delia Preti, Gaia Pedriali, Giorgio Aquila, Sonia Missiroli, Anna Fantinati, Natascia Caroccia, Salvatore Pacifico, Massimo Bonora, Anna Talarico, Claudia Morganti, Paola Rizzo, Roberto Ferrari, Mariusz R. Wieckowski, Gianluca Campo, Carlotta Giorgi, Claudio Trapella & Paolo Pinton. (2018) Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F 1 /F O -Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction . Journal of Medicinal Chemistry 61:16, pages 7131-7143.
Crossref
Kevin J Morris & Anita H Corbett. (2018) The polyadenosine RNA-binding protein ZC3H14 interacts with the THO complex and coordinately regulates the processing of neuronal transcripts. Nucleic Acids Research 46:13, pages 6561-6575.
Crossref
Magdalena Bachmann, Roberto Costa, Roberta Peruzzo, Elena Prosdocimi, Vanessa Checchetto & Luigi Leanza. (2018) Targeting Mitochondrial Ion Channels to Fight Cancer. International Journal of Molecular Sciences 19:7, pages 2060.
Crossref
María J. Pérez, Claudia Jara & Rodrigo A. Quintanilla. (2018) Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration. Frontiers in Neuroscience 12.
Crossref
E.F. Shevtsova, D.V. Vinogradova, M.E. Neganova, P.N. Shevtsov, B.V. Lednev & S.O. Bachurin. (2018) Mitochondria are an Important Target in the Search for new Drugs for the Treatment of Alzheimer′s Disease and Senile Dementia. Biomedical Chemistry: Research and Methods 1:3, pages e00058.
Crossref
Navneet Ammal Kaidery & Bobby Thomas. (2018) Current perspective of mitochondrial biology in Parkinson's disease. Neurochemistry International 117, pages 91-113.
Crossref
Christos Chinopoulos. (2018) Mitochondrial permeability transition pore: Back to the drawing board. Neurochemistry International 117, pages 49-54.
Crossref
Sara I. Zandalinas & Ron Mittler. (2018) ROS-induced ROS release in plant and animal cells. Free Radical Biology and Medicine 122, pages 21-27.
Crossref
Christopher P. Baines & Manuel Gutiérrez-Aguilar. (2018) The still uncertain identity of the channel-forming unit(s) of the mitochondrial permeability transition pore. Cell Calcium 73, pages 121-130.
Crossref
Artyom Y. Baev, Pia A. Elustondo, Alexander Negoda & Evgeny V. Pavlov. (2018) Osmotic regulation of the mitochondrial permeability transition pore investigated by light scattering, fluorescence and electron microscopy techniques. Analytical Biochemistry 552, pages 38-44.
Crossref
Jason Karch & Jeffery D Molkentin. (2018) Identity of the elusive mitochondrial permeability transition pore: what it might be, what it was, and what it still could be. Current Opinion in Physiology 3, pages 57-62.
Crossref
Paolo Bernardi & Giovanna Lippe. (2018) Channel formation by F-ATP synthase and the permeability transition pore: an update. Current Opinion in Physiology 3, pages 1-5.
Crossref
Salvatore Nesci. (2018) A Lethal Channel between the ATP Synthase Monomers. Trends in Biochemical Sciences 43:5, pages 311-313.
Crossref
Petr Pecina, Hana Nůsková, Vendula Karbanová, Vilma Kaplanová, Tomáš Mráček & Josef Houštěk. (2018) Role of the mitochondrial ATP synthase central stalk subunits γ and δ in the activity and assembly of the mammalian enzyme. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1859:5, pages 374-381.
Crossref
Lorenzo Galluzzi, Ilio Vitale, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V. Antonov, Eli Arama, Eric H. Baehrecke, Nickolai A. Barlev, Nicolas G. Bazan, Francesca Bernassola, Mathieu J. M. Bertrand, Katiuscia Bianchi, Mikhail V. Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K.-M. Chan, Navdeep S. Chandel, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gerald M. Cohen, Marcus Conrad, Juan R. Cubillos-Ruiz, Peter E. Czabotar, Vincenzo D’Angiolella, Ted M. Dawson, Valina L. Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J. DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M. Dixit, Scott J. Dixon, Colin S. Duckett, Brian D. Dynlacht, Wafik S. El-Deiry, John W. Elrod, Gian Maria Fimia, Simone Fulda, Ana J. García-Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J. Marie Hardwick, Isaac S. Harris, Michael O. Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J. Jost, Philippe P. Juin, William J. Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N. Kitsis, Daniel J. Klionsky, Richard A. Knight, Sharad Kumar, Sam W. Lee, John J. Lemasters, Beth Levine, Andreas Linkermann, Stuart A. Lipton, Richard A. Lockshin, Carlos López-Otín, Scott W. Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J. Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A. Miao, Jeffery D. Molkentin, Ute M. Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M. Penninger, David M. Pereira, Shazib Pervaiz, Marcus E. Peter, Mauro Piacentini, Paolo Pinton, Jochen H.M. Prehn, Hamsa Puthalakath, Gabriel A. Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M.P. Rodrigues, David C. Rubinsztein, Thomas Rudel, Kevin M. Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R. Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W.G. Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G. Vander Heiden, Andreas Villunger, Herbert W. Virgin, Karen H. Vousden, Domagoj Vucic, Erwin F. Wagner, Henning Walczak, David Wallach, Ying Wang, James A. Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino & Guido Kroemer. (2018) Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death & Differentiation 25:3, pages 486-541.
Crossref
Hong Zhu & Aijun Sun. (2018) Programmed necrosis in heart disease: Molecular mechanisms and clinical implications. Journal of Molecular and Cellular Cardiology 116, pages 125-134.
Crossref
Jiekun Xuan, Zhen Ren, Tao Qing, Letha Couch, Leming Shi, William H. Tolleson & Lei Guo. (2018) Mitochondrial dysfunction induced by leflunomide and its active metabolite. Toxicology 396-397, pages 33-45.
Crossref
Susana Cadenas. (2018) ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection. Free Radical Biology and Medicine 117, pages 76-89.
Crossref
Valentina Giorgio, Lishu Guo, Claudio Bassot, Valeria Petronilli & Paolo Bernardi. (2018) Calcium and regulation of the mitochondrial permeability transition. Cell Calcium 70, pages 56-63.
Crossref
Justyna Janikiewicz, Jędrzej Szymański, Dominika Malinska, Paulina Patalas-Krawczyk, Bernadeta Michalska, Jerzy Duszyński, Carlotta Giorgi, Massimo Bonora, Agnieszka Dobrzyn & Mariusz R. Wieckowski. (2018) Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics. Cell Death & Disease 9:3.
Crossref
Manuela Antoniel, Kristen Jones, Salvatore Antonucci, Barbara Spolaore, Federico Fogolari, Valeria Petronilli, Valentina Giorgio, Michela Carraro, Fabio Di Lisa, Michael Forte, Ildikó Szabó, Giovanna Lippe & Paolo Bernardi. (2017) The unique histidine in OSCP subunit of F‐ATP synthase mediates inhibition of the permeability transition pore by acidic pH. EMBO reports 19:2, pages 257-268.
Crossref
Katarzyna Niedzwiecka, Renata Tisi, Sara Penna, Malgorzata Lichocka, Danuta Plochocka & Roza Kucharczyk. (2018) Two mutations in mitochondrial ATP6 gene of ATP synthase, related to human cancer, affect ROS, calcium homeostasis and mitochondrial permeability transition in yeast. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:1, pages 117-131.
Crossref
J.C. Davila, S. Levin & Z.A. Radi. 2018. Comprehensive Toxicology. Comprehensive Toxicology 404 453 .
Claudia Morganti, Massimo Bonora, Luigi Sbano, Giampaolo Morciano, Giorgio Aquila, Gianluca Campo, Mariusz R. Wieckowski, Carlotta Giorgi & Paolo Pinton. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics 47 73 .
Filomena S. G. Silva, Cláudio F. Costa, Ricardo J. Marques, Paulo J. Oliveira & Gonçalo C. Pereira. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics 423 490 .
Giuseppe Federico Amodeo, Maria E. Solesio & Evgeny V. Pavlov. (2017) From ATP synthase dimers to C-ring conformational changes: unified model of the mitochondrial permeability transition pore. Cell Death & Disease 8:12.
Crossref
Gisela Beutner, Ryan E. Alanzalon & George A. PorterJr.Jr.. (2017) Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes. Scientific Reports 7:1.
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