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Special Focus Review

A case-study investigating the physicochemical characteristics that dictate the function of a liposomal adjuvant

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Pages 1374-1381 | Received 27 Mar 2013, Accepted 27 Mar 2013, Published online: 12 Apr 2013

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Sameer Joshi, Swapnil Bawage, Pooja Tiwari, Daniel Kirby, Yvonne Perrie, Vida Dennis & Shree R Singh. (2019) Liposomes: a promising carrier for respiratory syncytial virus therapeutics. Expert Opinion on Drug Delivery 16:9, pages 969-980.
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Wenjing Qu, Na Li, Rui Yu, Wenbao Zuo, Tingting Fu, Wenling Fei, Yanhui Hou, Yanhua Liu & Jianhong Yang. (2018) Cationic DDA/TDB liposome as a mucosal vaccine adjuvant for uptake by dendritic cells in vitro induces potent humoural immunity. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 852-860.
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Carl R. Alving, Zoltan Beck, Gary R. Matyas & Mangala Rao. (2016) Liposomal adjuvants for human vaccines. Expert Opinion on Drug Delivery 13:6, pages 807-816.
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Marcelle Carolina Colhone, Izaltina Silva-Jardim, Rodrigo Guerino Stabeli & Pietro Ciancaglini. (2015) Nanobiotechnologic approach to a promising vaccine prototype for immunisation against leishmaniasis: a fast and effective method to incorporate GPI-anchored proteins of Leishmania amazonensis into liposomes. Journal of Microencapsulation 32:2, pages 143-150.
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Aneesh Thakur, Abishek Wadhwa, Abhijeet Lokras, Olivia Amanda Oest Müllertz, Dennis Christensen, Henrik Franzyk & Camilla Foged. (2023) Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins. European Journal of Pharmaceutics and Biopharmaceutics 189, pages 84-97.
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R.J.T. Leboux, N. Benne, W.L. van Os, J. Bussmann, A. Kros, W. Jiskoot & B. Slütter. (2021) High-affinity antigen association to cationic liposomes via coiled coil-forming peptides induces a strong antigen-specific CD4+ T-cell response. European Journal of Pharmaceutics and Biopharmaceutics 158, pages 96-105.
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Cui Song, Feng Li, Shuang Wang, Jianghua Wang, Wei Wei & Guanghui Ma. (2019) Recent Advances in Particulate Adjuvants for Cancer Vaccination. Advanced Therapeutics 3:5, pages 1900115.
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Ellen K. Wasan, Jaweria Syeda, Stacy Strom, Jacqueline Cawthray, Robert E. Hancock, Kishor M. Wasan & Volker Gerdts. (2019) A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice. Vaccine 37:11, pages 1503-1515.
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Maria Chountoulesi, Nikolaos Naziris, Natassa Pippa, Stergios Pispas & Costas Demetzos. 2019. Thermodynamics and Biophysics of Biomedical Nanosystems. Thermodynamics and Biophysics of Biomedical Nanosystems 297 337 .
Sameer Joshi, Atul Chaudhari, Vida Dennis, Daniel Kirby, Yvonne Perrie & Shree Singh. (2018) Anti-RSV Peptide-Loaded Liposomes for the Inhibition of Respiratory Syncytial Virus. Bioengineering 5:2, pages 37.
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Raj Badhan, Swapnil Khadke & Yvonne Perrie. (2017) Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System. Pharmaceutics 9:4, pages 57.
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Ana Maria Carmona-Ribeiro. 2017. Application and Characterization of Surfactants. Application and Characterization of Surfactants.
Sonia Alavi, Azadeh Haeri & Simin Dadashzadeh. (2017) Utilization of chitosan-caged liposomes to push the boundaries of therapeutic delivery. Carbohydrate Polymers 157, pages 991-1012.
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Azadeh Haeri, Saeed Sadeghian, Shahram Rabbani, Shapour Shirani, Maryam Sotoudeh Anvari & Simin Dadashzadeh. (2017) Physicochemical characteristics of liposomes are decisive for their antirestenosis efficacy following local delivery. Nanomedicine 12:2, pages 131-145.
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Yvonne Perrie, Elisabeth Kastner, Swapnil Khadke, Carla B. Roces & Peter Stone. 2017. Vaccine Adjuvants. Vaccine Adjuvants 127 144 .
Zoltan Beck, Gary R. Matyas, Rashmi Jalah, Mangala Rao, Victoria R. Polonis & Carl R. Alving. (2015) Differential immune responses to HIV-1 envelope protein induced by liposomal adjuvant formulations containing monophosphoryl lipid A with or without QS21. Vaccine 33:42, pages 5578-5587.
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Peter C. Soema, Geert-Jan Willems, Wim Jiskoot, Jean-Pierre Amorij & Gideon F. Kersten. (2015) Predicting the influence of liposomal lipid composition on liposome size, zeta potential and liposome-induced dendritic cell maturation using a design of experiments approach. European Journal of Pharmaceutics and Biopharmaceutics 94, pages 427-435.
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Ruchi R. Shah, Stephanie Dodd, Mary Schaefer, Mildred Ugozzoli, Manmohan Singh, Gillis R. Otten, Mansoor M. Amiji, Derek T. O’hagan & Luis A. Brito. (2015) The Development of Self-Emulsifying Oil-in-Water Emulsion Adjuvant and an Evaluation of the Impact of Droplet Size on Performance. Journal of Pharmaceutical Sciences 104:4, pages 1352-1361.
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D.W. Horohov, J. Dunham, C. Liu, A. Betancourt, J.C. Stewart, A.E. Page & T.M. Chambers. (2015) Characterization of the in situ immunological responses to vaccine adjuvants. Veterinary Immunology and Immunopathology 164:1-2, pages 24-29.
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Catarina Carneiro, Alexandra Correia, Tony Collins, Manuel Vilanova, Célia Pais, Andreia C. Gomes, M. Elisabete C.D. Real Oliveira & Paula Sampaio. (2015) DODAB:monoolein liposomes containing Candida albicans cell wall surface proteins: A novel adjuvant and delivery system. European Journal of Pharmaceutics and Biopharmaceutics 89, pages 190-200.
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Heleen Dewitte, Rein Verbeke, Karine Breckpot, Stefaan C. De Smedt & Ine Lentacker. (2014) Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment. Nano Today 9:6, pages 743-758.
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Mohammed Jubair Hussain, Alexander Wilkinson, Vincent W Bramwell, Dennis Christensen & Yvonne Perrie. (2014) Th1 immune responses can be modulated by varying dimethyldioctadecylammonium and distearoyl-sn-glycero-3-phosphocholine content in liposomal adjuvants. Journal of Pharmacy and Pharmacology 66:3, pages 358-366.
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Christophe Barnier-Quer, Abdelrahman Elsharkawy, Stefan Romeijn, Alexander Kros & Wim Jiskoot. (2013) Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators. Pharmaceutics 5:4, pages 392-410.
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