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Human Vaccines & Immunotherapeutics Volume 9, 2013 - Issue 10
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Research Paper

NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses

Maarten A Ligtenberg Immune and Gene Therapy Laboratory; Cancer Center Karolinska; Department of Oncology and Pathology; Karolinska Institutet; Stockholm, Sweden
,
Nicole Rojas-Colonelli Laboratory of Gene Immunotherapy; Fundación Ciencia & Vida; Santiago, Chile; Facultad de Ciencias Biológicas; Universidad Andrés Bello; Santiago, Chile
,
Rolf Kiessling Immune and Gene Therapy Laboratory; Cancer Center Karolinska; Department of Oncology and Pathology; Karolinska Institutet; Stockholm, Sweden
&
Alvaro Lladser Laboratory of Gene Immunotherapy; Fundación Ciencia & Vida; Santiago, Chile; Programa de Biomedicina; Universidad San Sebastián; Santiago, ChileCorrespondence[email protected]
Pages 2189-2195 | Received 25 Mar 2013, Accepted 10 Jul 2013, Published online: 24 Jul 2013

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Yu Wang, Weiwei Song, Qiang Xu, Yachao Liu, Hezhong Liu, Runzi Guo, Chuang-Jiun Chiou, Kun Gao, Baofeng Jin, Changfeng Chen, Zhongming Li, Jinqi Yan & Jiyun Yu. (2023) Adjuvant DNA vaccine pNMM promotes enhanced specific immunity and anti-tumor effects. Human Vaccines & Immunotherapeutics 19:1.
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M. A. Ligtenberg, K. Witt, F. Galvez-Cancino, A. Sette, A. Lundqvist, A. Lladser & R. Kiessling. (2016) Cripto-1 vaccination elicits protective immunity against metastatic melanoma. OncoImmunology 5:5.
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Kenneth Ugen & David B Weiner. (2013) DNA vaccines onward and upward! 20 years and counting! Highlights of the DNA Vaccines 2012 Meeting. Human Vaccines & Immunotherapeutics 9:10, pages 2038-2040.
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Pablo Cáceres-Morgado & Alvaro Lladser. 2021. DNA Vaccines. DNA Vaccines 225 239 .
Lucille Adam, Nicolas Tchitchek, Biliana Todorova, Pierre Rosenbaum, Candie Joly, Candice Poux, Catherine Chapon, Anna-Lena Spetz, Mart Ustav, Roger Le Grand & Frédéric Martinon. (2020) Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination. The Journal of Immunology 204:12, pages 3375-3388.
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Yao-Hua Liu, I-Jeng Yeh, Ming-Derg Lai, Kuan-Ting Liu, Po-Lin Kuo & Meng-Chi Yen. (2019) Cancer Immunotherapy: Silencing Intracellular Negative Immune Regulators of Dendritic Cells. Cancers 11:1, pages 108.
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Tamara TyrinovaOlga LeplinaSergey MishinovMarina TikhonovaAnton KalinovskiySergey ChernovEvgeniya DolgovaVyacheslav StupakEvgeniya VoroninaSergey BogachevEkaterina ShevelaAlexander OstaninElena Chernykh. (2018) Defective Dendritic Cell Cytotoxic Activity of High-Grade Glioma Patients' Results from the Low Expression of Membrane TNFα and Can Be Corrected In Vitro by Treatment with Recombinant IL-2 or Exogenic Double-Stranded DNA . Journal of Interferon & Cytokine Research 38:7, pages 298-310.
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Mariela A. Moreno Ayala, María Florencia Gottardo, María Soledad Gori, Alejandro Javier Nicola Candia, Carla Caruso, Andrea De Laurentiis, Mercedes Imsen, Slobodanka Klein, Elisa Bal de Kier Joffé, Gabriela Salamone, Maria G. Castro, Adriana Seilicovich & Marianela Candolfi. (2017) Dual activation of Toll-like receptors 7 and 9 impairs the efficacy of antitumor vaccines in murine models of metastatic breast cancer. Journal of Cancer Research and Clinical Oncology 143:9, pages 1713-1732.
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Felipe Gálvez-Cancino, Jonathan Roco, Nicole Rojas-Colonelli, Camila Flores, Paola Murgas, Sebastián Cruz-Gómez, César Oyarce, Manuel Varas-Godoy, Daniela Sauma & Alvaro Lladser. (2017) A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination. Vaccine 35:33, pages 4148-4154.
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Dionisia Quiroga, Yasser A. Aldhamen, Sarah Godbehere, Laura Harding & Andrea Amalfitano. (2017) Decreased Vector Gene Expression from E2b Gene-Deleted Adenovirus Serotype 5 Vaccines Intensifies Proinflammatory Immune Responses. Clinical and Vaccine Immunology 24:6.
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Haifeng Wang, Kan Gao, Ke Wen, Irving Coy Allen, Guohua Li, Wenming Zhang, Jacob Kocher, Xingdong Yang, Ernawati Giri-Rachman, Guan-Hong Li, Sherrie Clark-Deener & Lijuan Yuan. (2016) Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. BMC Microbiology 16:1.
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Kristen P. Zeligs, Monica K. Neuman & Christina M. Annunziata. (2016) Molecular Pathways: The Balance between Cancer and the Immune System Challenges the Therapeutic Specificity of Targeting Nuclear Factor-κB Signaling for Cancer Treatment. Clinical Cancer Research 22:17, pages 4302-4308.
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Angeliki Tiptiri-Kourpeti, Katerina Spyridopoulou, Aglaia Pappa & Katerina Chlichlia. (2016) DNA vaccines to attack cancer: Strategies for improving immunogenicity and efficacy. Pharmacology & Therapeutics 165, pages 32-49.
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Mohammad Alsaggar & Dexi Liu. 2015. Nonviral Vectors for Gene Therapy - Physical Methods and Medical Translation. Nonviral Vectors for Gene Therapy - Physical Methods and Medical Translation 1 24 .
Kenneth Lundstrom. 2015. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 15 39 .

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