4,343
Views
92
CrossRef citations to date
0
Altmetric
Review

Monoclonal antibodies in neuro-oncology

Getting past the blood-brain barrier

Pages 153-160 | Received 10 Dec 2010, Accepted 19 Nov 2010, Published online: 01 Mar 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Mariantonia Logozzi, Rossella Di Raimo, Francesca Properzi, Stefano Barca, Daniela F. Angelini, Davide Mizzoni, Mario Falchi, Luca Battistini & Stefano Fais. (2021) Nanovesicles released by OKT3 hybridoma express fully active antibodies. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 175-182.
Read now
Mafalda Oliveira, Laia Garrigós, Juan David Assaf, Santiago Escrivá-de-Romaní & Cristina Saura. (2020) Neratinib plus capecitabine for the treatment of advanced HER2-positive breast cancer. Expert Review of Anticancer Therapy 20:9, pages 731-741.
Read now
Rima Ait-Belkacem, Caroline Berenguer, Claude Villard, L’Houcine Ouafik, Dominique Figarella-Branger, Alain Beck, Olivier Chinot & Daniel Lafitte. (2014) Monitoring therapeutic monoclonal antibodies in brain tumor. mAbs 6:6, pages 1385-1393.
Read now
Hans Skovgaard Poulsen, Thomas Urup, Signe Regner Michaelsen, Mikkel Staberg, Mette Villingshøj & Ulrik Lassen. (2014) The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients. Cancer Management and Research 6, pages 373-387.
Read now
Josée Golay, Gianpietro Semenzato, Alessandro Rambaldi, Robin Foà, Gianluca Gaidano, Enrica Gamba, Fabrizio Pane, Antonello Pinto, Giorgina Specchia, Francesco Zaja & Mario Regazzi. (2013) Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics. mAbs 5:6, pages 826-837.
Read now
Alexey A. Lugovskoy, Janice M. Reichert & Alain Beck. (2012) 7th Annual European Antibody Congress 2011. mAbs 4:2, pages 134-152.
Read now

Articles from other publishers (86)

Iris H. C. Miedema, Jessica E. Wijngaarden, Johanna E. E. Pouw, Gerben J. C. Zwezerijnen, Hylke J. Sebus, Egbert Smit, Adrianus J. de Langen, Idris Bahce, Andrea Thiele, Daniëlle J. Vugts, Ronald Boellaard, Marc C. Huisman & C. Willemien Menke-van der Houven van Oordt. (2023) 89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs. Cancers 15:23, pages 5546.
Crossref
Meaghan McGovern, Michaela Scanlon, Amanda Stanton & Brandon Lucke-Wold. (2023) An introductory review of post-resection chemotherapeutics for primary brain tumors. Exploration of Targeted Anti-tumor Therapy, pages 537-544.
Crossref
Yuhang Zhang, Zhihe Liu, Chengwen Gao, Haiyan Bian, Yushuo Ma, Fanjing Jing & Xia Zhao. (2023) Role of Rituximab in Treatment of Patients With Primary Central Nervous System Lymphoma (PCNSL): A Systematic Review and Meta-Analysis. Clinical Lymphoma Myeloma and Leukemia.
Crossref
Karrie Mei-Yee Kiang, Wanjun Tang, Qingchun Song, Jiaxin Liu, Ning Li, Tsz-Lung Lam, Ho Cheung Shum, Zhiyuan Zhu & Gilberto Ka-Kit Leung. (2023) Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma. British Journal of Cancer 128:10, pages 1955-1963.
Crossref
Hossam Nada, Aneesh Sivaraman, Qili Lu, Kyoungho Min, Sungdo Kim, Ja-Il Goo, Yongseok Choi & Kyeong Lee. (2023) Perspective for Discovery of Small Molecule IL-6 Inhibitors through Study of Structure–Activity Relationships and Molecular Docking. Journal of Medicinal Chemistry.
Crossref
Stefaan W. Van Gool, Jennifer Makalowski, Peter Van de Vliet, Stefanie Van Gool, Tobias Sprenger, Volker Schirrmacher & Wilfried Stuecker. (2023) Individualized Multimodal Immunotherapy for Adults with IDH1 Wild-Type GBM: A Single Institute Experience. Cancers 15:4, pages 1194.
Crossref
Mireille Elodie Tsitokana, Pierre-André Lafon, Laurent Prézeau, Jean-Philippe Pin & Philippe Rondard. (2023) Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?. International Journal of Molecular Sciences 24:3, pages 2632.
Crossref
Ilaria Callegari, Mika Schneider, Vera Aebischer, Margarete M. Voortman, Undine Proschmann, Tjalf Ziemssen, Raija Lindberg, Bettina Fischer-Barnicol, Michael Khalil, Ludwig Kappos, Jens Kuhle, Nicholas S.R. Sanderson & Tobias Derfuss. (2023) Natalizumab in cerebrospinal fluid and breastmilk of patients with multiple sclerosis. Therapeutic Advances in Neurological Disorders 16, pages 175628642211500.
Crossref
Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Nan Qin, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Allison Cole, Joselyn Cruz-Cruz, Claus M Graef, Matthias Wölfl, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Stephen T Keir, Darell D Bigner, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Arndt Borkhardt, Thomas Kurz, Marc Remke & Siddhartha Mitra. (2023) Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation. Journal for ImmunoTherapy of Cancer 11:1, pages e005871.
Crossref
Colin P Sperring, Michael G Argenziano, William M Savage, Damian E Teasley, Pavan S Upadhyayula, Nathan J Winans, Peter Canoll & Jeffrey N Bruce. (2023) Convection-enhanced delivery of immunomodulatory therapy for high-grade glioma. Neuro-Oncology Advances 5:1.
Crossref
James W. Beattie, Alena Istrate, Annabelle Lu, Cameron Marshall, Ruth C. Rowland-Jones, Monika Farys, Sergei G. Kazarian & Bernadette Byrne. (2022) Causes of Industrial Protein A Column Degradation, Explored Using Raman Spectroscopy. Analytical Chemistry 94:45, pages 15703-15710.
Crossref
Iris Tung, Cristina Moldovan, Vanessa Wong, Richard De Boer, Belinda Yeo, Laeeq Malik, Sally Greenberg, Angelyn Anton, Louise Nott, Frances Barnett, Ian M Collins, Janine Lombard, Michelle Nottage, Arvind Sahu, Javier Torres, Peter Gibbs & Sheau Wen Lok. (2022) Real-World Outcomes in Patients With Brain Metastases Secondary to HER2-Positive Breast Cancer: An Australian Multi-centre Registry-based Study. Clinical Breast Cancer 22:7, pages e764-e772.
Crossref
Ksenia Mitusova, Oleksii O. Peltek, Timofey E. Karpov, Albert R. Muslimov, Mikhail V. Zyuzin & Alexander S. Timin. (2022) Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches. Journal of Nanobiotechnology 20:1.
Crossref
Elshad Hasanov, Debra Nana Yeboa, Mathew D. Tucker, Todd A. Swanson, Thomas Hendrix Beckham, Brian Rini, Chibawanye I. Ene, Merve Hasanov, Sophie Derks, Marion Smits, Shaan Dudani, Daniel Y. C. Heng, Priscilla K. Brastianos, Axel Bex, Sahin Hanalioglu, Jeffrey S. Weinberg, Laure Hirsch, Maria I. Carlo, Ayal Aizer, Paul David Brown, Mehmet Asim Bilen, Eric Lin Chang, Jerry Jaboin, James Brugarolas, Toni K. Choueiri, Michael B. Atkins, Bradley A. McGregor, Lia M. Halasz, Toral R. Patel, Scott G. Soltys, David F. McDermott, James Bradley Elder, Mustafa K. Baskaya, James B. Yu, Robert Timmerman, Michelle Miran Kim, Melike Mut, James Markert, Kathryn Beal, Nizar M. Tannir, George Samandouras, Frederick F. Lang, Rachel Giles & Eric Jonasch. (2022) An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma. CA: A Cancer Journal for Clinicians 72:5, pages 454-489.
Crossref
Raphaël Le Biannic, Romain Magnez, Frédérique Klupsch, Natascha Leleu-Chavain, Bryan Thiroux, Morgane Tardy, Hassiba El Bouazzati, Xavier Dezitter, Nicolas Renault, Gérard Vergoten, Christian Bailly, Bruno Quesnel, Xavier Thuru & Régis Millet. (2022) Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction. European Journal of Medicinal Chemistry 236, pages 114343.
Crossref
Michael Boettcher, Alexander Joechner, Ziduo Li, Sile Fiona Yang & Patrick Schlegel. (2022) Development of CAR T Cell Therapy in Children—A Comprehensive Overview. Journal of Clinical Medicine 11:8, pages 2158.
Crossref
Haneen Shalabi, Anandani Nellan, Nirali N. Shah & Juliane Gust. (2022) Immunotherapy Associated Neurotoxicity in Pediatric Oncology. Frontiers in Oncology 12.
Crossref
Malcolm Lim, Tam H. Nguyen, Colleen Niland, Lynne E. Reid, Parmjit S. Jat, Jodi M. Saunus & Sunil R. Lakhani. (2022) Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases. Cancers 14:3, pages 533.
Crossref
Lauren D. Scherer & Eric S. Schafer. 2022. Clinical Management of Acute Lymphoblastic Leukemia. Clinical Management of Acute Lymphoblastic Leukemia 235 265 .
Jorge Correale, Mario Javier Halfon, Dominic Jack, Adrián Rubstein & Andrés Villa. (2021) Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis. Multiple Sclerosis and Related Disorders 56, pages 103264.
Crossref
Jessica Kalra, Jennifer Baker, Justin Song, Alastair Kyle, Andrew Minchinton & Marcel Bally. (2021) Inter-Metastatic Heterogeneity of Tumor Marker Expression and Microenvironment Architecture in a Preclinical Cancer Model. International Journal of Molecular Sciences 22:12, pages 6336.
Crossref
Alejandro Garcia-Alvarez, Andri Papakonstantinou & Mafalda Oliveira. (2021) Brain Metastases in HER2-Positive Breast Cancer: Current and Novel Treatment Strategies. Cancers 13:12, pages 2927.
Crossref
Panagiotis Gklinos, Miranta Papadopoulou, Vid Stanulovic, Dimos D. Mitsikostas & Dimitrios Papadopoulos. (2021) Monoclonal Antibodies as Neurological Therapeutics. Pharmaceuticals 14:2, pages 92.
Crossref
Yue Ren, Shan-Bing Wang, Lin Zhou, Si-Qiao Liu, Lei-Ya Du, Ting Li, Mao-Qiong Jiang, Kai-Jian Lei, Bang-Xian Tan & Yu-Ming Jia. (2021) Continuous Low-Dose Apatinib Combined With WBRT Significantly Reduces Peritumoral Edema and Enhances the Efficacy of Symptomatic Multiple Brain Metastases in NSCLC. Technology in Cancer Research & Treatment 20, pages 153303382110119.
Crossref
Joe A. Fralick & Jason Clark. 2021. Bacteriophages. Bacteriophages 1031 1067 .
Nazanin K. Majd, Pushan R. Dasgupta & John F. de Groot. 2021. Immunotherapy. Immunotherapy 233 258 .
Long Wang, Gengyuan Zhang, Long Qin, Huili Ye, Yan Wang, Bo Long & Zuoyi Jiao. (2020) Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours. Recent Patents on Anti-Cancer Drug Discovery 15:3, pages 200-211.
Crossref
Takayuki Tanaka, Kengo Kanetaka, Takahiro Ikeda, Shun Yamaguchi, Syunsuke Kawakami, Tomoo Kitajima, Toru Iwata & Susumu Eguchi. (2020) A rare case of meningeal carcinomatosis and internal auditory canal metastasis presenting with the deafness for gastric cancer. Surgical Case Reports 6:1.
Crossref
Hua Yang, Yang Xun, Anping Yang, Fang Liu & Hua You. (2020) Advances and challenges in the treatment of primary central nervous system lymphoma. Journal of Cellular Physiology 235:12, pages 9143-9165.
Crossref
Tiara S. Napier, Neha Udayakumar, Aditi H. Jani, Yolanda E. Hartman, Hailey A. Houson, Lindsay Moore, Hope M. Amm, Nynke S. van den Berg, Anna G. Sorace & Jason M. Warram. (2020) Comparison of Panitumumab-IRDye800CW and 5-Aminolevulinic Acid to Provide Optical Contrast in a Model of Glioblastoma Multiforme. Molecular Cancer Therapeutics 19:9, pages 1922-1929.
Crossref
Nerea Lopetegui‐Lia, Lukas Delasos, Syed Daniyal Asad, Manish Kumar & Jonathan S. Harrison. (2020) Primary central nervous system marginal zone B‐cell lymphoma arising from the dural meninges: A case report and review of literature. Clinical Case Reports 8:3, pages 491-497.
Crossref
Ilanah J. Pruis, Guus A. M. S. van Dongen & Sophie E. M. Veldhuijzen van Zanten. (2020) The Added Value of Diagnostic and Theranostic PET Imaging for the Treatment of CNS Tumors. International Journal of Molecular Sciences 21:3, pages 1029.
Crossref
Joe A. Fralick & Jason Clark. 2020. Bacteriophages. Bacteriophages 1 38 .
Nazanin Majd, Pushan Dasgupta & John de Groot. 2020. Immunotherapy. Immunotherapy 183 203 .
Mustafa S. Ascha, Jacqueline Fang Wang, Priya Kumthekar, Andrew E. Sloan, Carol Kruchko & Jill S. Barnholtz-Sloan. (2019) Bevacizumab for the treatment of non-small cell lung cancer patients with synchronous brain metastases. Scientific Reports 9:1.
Crossref
Kota Takemoto, Nobuyuki Miyahara, Nobuyuki Chikuie, Takao Hamamoto, Takashi Ishino, Tsutomu Ueda & Sachio Takeno. (2019) Efficacy of anti-PD-1 therapy in a patient with brain metastasis of parotid carcinoma: A case report. Auris Nasus Larynx 46:5, pages 813-817.
Crossref
Timour Al-Khindi, Colette J. Shen, Luke Peng, Kristin J. Redmond, Michael Lim, Lawrence R. Kleinberg & Chetan Bettegowda. (2019) Assessing the Effectiveness of Systemic Therapy after Stereotactic Radiosurgery on Cancer Recurrence and All-Cause Mortality. World Neurosurgery 129, pages e572-e581.
Crossref
Pia MontanucciLuigi CariGiuseppe BastaTeresa PescaraCarlo RiccardiGiuseppe NocentiniRiccardo Calafiore. (2019) Engineered Alginate Microcapsules for Molecular Therapy Through Biologic Secreting Cells. Tissue Engineering Part C: Methods 25:5, pages 296-304.
Crossref
Lei Han, Chaoyong Liu, Hongzhao Qi, Junhu Zhou, Jing Wen, Di Wu, Duo Xu, Meng Qin, Jie Ren, Qixue Wang, Lixia Long, Yang Liu, Irvin Chen, Xubo Yuan, Yunfeng Lu & Chunsheng Kang. (2019) Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy. Advanced Materials 31:19, pages 1805697.
Crossref
Nicolas Collongues, Estelle Ayme-Dietrich, Laurent Monassier & Jérôme de Seze. (2019) Pharmacotherapy for Neuromyelitis Optica Spectrum Disorders: Current Management and Future Options. Drugs 79:2, pages 125-142.
Crossref
Vijith Shetty & Suresh Babu. (2019) Management of CNS metastases in patients with EGFR mutation-positive NSCLC. Indian Journal of Cancer 56:5, pages 31.
Crossref
James D’Rozario & Samuel K. Bennett. (2019) Update on the role of venetoclax and rituximab in the treatment of relapsed or refractory CLL. Therapeutic Advances in Hematology 10, pages 204062071984469.
Crossref
Suneel D. Kamath & Priya U. Kumthekar. (2018) Immune Checkpoint Inhibitors for the Treatment of Central Nervous System (CNS) Metastatic Disease. Frontiers in Oncology 8.
Crossref
Xuyao Zhang, Wei Chen, Jiajun Fan, Shaofei Wang, Zongshu Xian, Jingyun Luan, Yubin Li, Yichen Wang, Yanyang Nan, Man Luo, Song Li, Wenzhi Tian & Dianwen Ju. (2018) Disrupting CD47-SIRPα axis alone or combined with autophagy depletion for the therapy of glioblastoma. Carcinogenesis 39:5, pages 689-699.
Crossref
Lois A. Lampson. (2018) Editorial: Immunotherapy for Tumor in the Brain: Insights From—and For—Other Tumor Sites. Frontiers in Oncology 8.
Crossref
Melanie-Jane Hannocks, Michelle E Pizzo, Jula Huppert, Tushar Deshpande, N Joan Abbott, Robert G Thorne & Lydia Sorokin. (2017) Molecular characterization of perivascular drainage pathways in the murine brain. Journal of Cerebral Blood Flow & Metabolism 38:4, pages 669-686.
Crossref
Adel Samson, Karen J. ScottDavid Taggart, Emma J. WestErica Wilson, Gerard J. Nuovo, Simon Thomson, Robert CornsRyan K. Mathew, Martin J. FullerTimothy J. KottkeJill M. ThompsonElizabeth J. Ilett, Julia V. Cockle, Philip van HilleGnanamurthy SivakumarEuan S. PolsonSamantha J. Turnbull, Elizabeth S. AppletonGemma MignecoAilsa S. Rose, Matthew C. CoffeyDeborah A. Beirne, Fiona J. CollinsonChristy Ralph, D. Alan Anthoney, Christopher J. TwelvesAndrew J. FurnessSergio A. Quezada, Heiko Wurdak, Fiona Errington-Mais, Hardev PandhaKevin J. HarringtonPeter J. Selby, Richard G. VileStephen D. Griffin, Lucy F. Stead, Susan C. Short & Alan A. Melcher. (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine 10:422.
Crossref
Flávia Sousa, Rui P. Moura, Elias Moreira, Cláudia Martins & Bruno Sarmento. 2018. Therapeutic Proteins and Peptides. Therapeutic Proteins and Peptides 61 80 .
Mohammad Ali Sahraian, Abdorreza Naser Moghadasi, Amir Reza Azimi, Nasrin Asgari, Fahimeh H. Akhoundi, Roya Abolfazli, Shekoofeh Alaie, Fereshteh Ashtari, Hormoz Ayromlou, Seyed Mohammad Baghbanian, Nahid Beladi Moghadam, Farzad Fatehi, Mohsen Foroughipour, Hamidreza Ghalyanchi Langroodi, Nastaran Majdinasab, Alireza Nickseresht, Abbas Nourian, Vahid Shaygannejad & Hamid Reza Torabi. (2017) Diagnosis and management of Neuromyelitis Optica Spectrum Disorder (NMOSD) in Iran: A consensus guideline and recommendations. Multiple Sclerosis and Related Disorders 18, pages 144-151.
Crossref
Tori B. Terrell-Hall, Mohamed Ismail Nounou, Fatema El-Amrawy, Jessica I.G. Griffith & Paul R. Lockman. (2017) Trastuzumab distribution in an in-vivo and in-vitro model of brain metastases of breast cancer . Oncotarget 8:48, pages 83734-83744.
Crossref
Manfred Westphal, Cecile L. Maire & Katrin Lamszus. (2017) EGFR as a Target for Glioblastoma Treatment: An Unfulfilled Promise. CNS Drugs 31:9, pages 723-735.
Crossref
Chen Fu, Dan S. Gombos, Jared Lee, Goldy C. George, Kenneth Hess, Andrew Whyte & David S. Hong. (2017) Ocular toxicities associated with targeted anticancer agents: an analysis of clinical data with management suggestions. Oncotarget 8:35, pages 58709-58727.
Crossref
Paul F. Rühle, Nicole Goerig, Roland Wunderlich, Rainer Fietkau, Udo S. Gaipl, Annedore Strnad & Benjamin Frey. (2017) Modulations in the Peripheral Immune System of Glioblastoma Patient Is Connected to Therapy and Tumor Progression—A Case Report from the IMMO-GLIO-01 Trial. Frontiers in Neurology 8.
Crossref
Nicolas Collongues, Laure Michel & J?r?me de Seze. (2017) Biotherapy in Inflammatory Diseases of the CNS: Current Knowledge and Applications. Current Treatment Options in Neurology 19:5.
Crossref
Sharareh Gholamin, Siddhartha S. Mitra, Abdullah H. Feroze, Jie LiuSuzana A. Kahn, Michael Zhang, Rogelio Esparza, Chase RichardVijay RamaswamyMarc RemkeAnne K. Volkmer, Stephen WillinghamAnitha Ponnuswami, Aaron McCartyPatricia LovelaceTheresa A. Storm, Simone SchubertGregor Hutter, Cyndhavi Narayanan, Pauline ChuEric H. Raabe, Griffith HarshIVIVMichael D. TaylorMichelle MonjeYoon-Jae ChoRavi MajetiJens P. VolkmerPaul G. Fisher, Gerald Grant, Gary K. SteinbergHannes VogelMichael EdwardsIrving L. WeissmanSamuel H. Cheshier. (2017) Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors. Science Translational Medicine 9:381.
Crossref
Surasak Phuphanich, Jeffrey Raizer, Marc Chamberlain, Paola Canelos, Rajesh Narwal, Shengyan Hong, Robert Miday, Minal Nade & Kevin Laubscher. (2016) Phase II study of MEDI-575, an anti-platelet-derived growth factor-α antibody, in patients with recurrent glioblastoma. Journal of Neuro-Oncology 131:1, pages 185-191.
Crossref
Jason Miska, Aida Rashidi, Alan L. Chang, Megan E. Muroski, Yu Han, Lingjiao Zhang & Maciej S. Lesniak. (2016) Anti-GITR therapy promotes immunity against malignant glioma in a murine model. Cancer Immunology, Immunotherapy 65:12, pages 1555-1567.
Crossref
Peter Ballard, James W.T. Yates, Zhenfan Yang, Dong-Wan Kim, James Chih-Hsin Yang, Mireille Cantarini, Kathryn Pickup, Angela Jordan, Mike Hickey, Matthew Grist, Matthew Box, Peter Johnström, Katarina Varnäs, Jonas Malmquist, Kenneth S. Thress, Pasi A. Jänne & Darren Cross. (2016) Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity. Clinical Cancer Research 22:20, pages 5130-5140.
Crossref
Jonathan Khalifa, Arya Amini, Sanjay Popat, Laurie E. Gaspar & Corinne Faivre-Finn. (2016) Brain Metastases from NSCLC: Radiation Therapy in the Era of Targeted Therapies. Journal of Thoracic Oncology 11:10, pages 1627-1643.
Crossref
A. G. de Lucas, A. J. Schuhmacher, M. Oteo, E. Romero, J. A. Cámara, A. de Martino, A. G. Arroyo, M. Á. Morcillo, M. Squatrito, J. L. Martinez-Torrecuadrada & F. Mulero. (2016) Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas. PLOS ONE 11:7, pages e0158634.
Crossref
Nicolas Collongues & Jérôme de Seze. (2016) An update on the evidence for the efficacy and safety of rituximab in the management of neuromyelitis optica. Therapeutic Advances in Neurological Disorders 9:3, pages 180-188.
Crossref
Henry J.M. Ferguson, Joseph W. Wragg, Stephen Ward, Victoria L. Heath, Tariq Ismail & Roy Bicknell. (2016) Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer. Oncotarget 7:15, pages 20440-20454.
Crossref
Nadia Pasinetti, Luigi Pirtoli, Michela Buglione, Luca Triggiani, Paolo Borghetti, Paolo Tini & Stefano Maria Magrini. 2016. Radiobiology of Glioblastoma. Radiobiology of Glioblastoma 275 292 .
Hiroaki Kurihara, Akinobu Hamada, Masayuki Yoshida, Schuichi Shimma, Jun Hashimoto, Kan Yonemori, Hitomi Tani, Yasuji Miyakita, Yousuke Kanayama, Yasuhiro Wada, Makoto Kodaira, Mayu Yunokawa, Harukaze Yamamoto, Chikako Shimizu, Kazuhiro Takahashi, Yasuyoshi Watanabe, Yasuhiro Fujiwara & Kenji Tamura. (2015) 64Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients. EJNMMI Research 5:1.
Crossref
Martha W. den Hollander, Frederike Bensch, Andor W.J.M. Glaudemans, Thijs H. Oude Munnink, Roelien H. Enting, Wilfred F.A. den Dunnen, Mart A.A.M. Heesters, Frank A.E. Kruyt, Marjolijn N. Lub-de Hooge, Jan Cees de Groot, Joseph Pearlberg, Jourik A. Gietema, Elisabeth G.E. de Vries & Annemiek M.E. Walenkamp. (2015) TGF-β Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89 Zr-Fresolimumab PET . Journal of Nuclear Medicine 56:9, pages 1310-1314.
Crossref
Manfred Westphal, Oliver Heese, Joachim P. Steinbach, Oliver Schnell, Gabriele Schackert, Maximilian Mehdorn, Dirk Schulz, Matthias Simon, Uwe Schlegel, Christian Senft, Karsten Geletneky, Christian Braun, Joachim G. Hartung, Dirk Reuter, Monika Warmuth Metz, Ferdinand Bach & Torsten Pietsch. (2015) A randomised, open label phase III trial with nimotuzumab, an anti-epidermal growth factor receptor monoclonal antibody in the treatment of newly diagnosed adult glioblastoma. European Journal of Cancer 51:4, pages 522-532.
Crossref
Rong Wang, Wenli Chen, Qiang Zhang, Yong Liu, Xiaoyun Qiao, Kui Meng & Ying Mao. (2014) Phosphodiesterase type 5 inhibitor Tadalafil increases Rituximab treatment efficacy in a mouse brain lymphoma model. Journal of Neuro-Oncology 122:1, pages 35-42.
Crossref
David P. Kodack, Vasileios Askoxylakis, Gino B. Ferraro, Dai Fukumura & Rakesh K. Jain. (2015) Emerging Strategies for Treating Brain Metastases from Breast Cancer. Cancer Cell 27:2, pages 163-175.
Crossref
Daniel J. Wolak, Michelle E. Pizzo & Robert G. Thorne. (2015) Probing the extracellular diffusion of antibodies in brain using in vivo integrative optical imaging and ex vivo fluorescence imaging. Journal of Controlled Release 197, pages 78-86.
Crossref
Andrew D. Norden, David Schiff, Manmeet S. Ahluwalia, Glenn J. Lesser, Lakshmi Nayak, Eudocia Q. Lee, Mikael L. Rinne, Alona Muzikansky, Jorg Dietrich, Benjamin Purow, Lisa M. Doherty, Debra C. LaFrankie, Julee R. Pulverenti, Jennifer A. Rifenburg, Sandra F. Ruland, Katrina H. Smith, Sarah C. Gaffey, Christine McCluskey, Keith L. Ligon, David A. Reardon & Patrick Y. Wen. (2014) Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas. Journal of Neuro-Oncology 121:2, pages 297-302.
Crossref
CHANG-HEE KIM, JUNG EUN SHIN, HONG GEE ROH, JONG SIK LEE & SO YOUNG YOON. (2014) Sudden hearing loss due to internal auditory canal metastasis of Her2-positive gastric cancer: A case report. Oncology Letters 8:1, pages 394-396.
Crossref
Rafal M. Kaminski, Michael A. Rogawski & Henrik Klitgaard. (2014) The Potential of Antiseizure Drugs and Agents that Act on Novel Molecular Targets as Antiepileptogenic Treatments. Neurotherapeutics 11:2, pages 385-400.
Crossref
Simone GaedickeFriederike BraunShruthi PrasadMarcia MacheinElke FiratMichael HettichRavindra GudihalXuekai ZhuKerstin KlingnerJulia SchülerChristel C. Herold-MendeAnca-Ligia GrosuMartin Behe, Wolfgang Weber, Helmut MäckeGabriele Niedermann. (2014) Noninvasive positron emission tomography and fluorescence imaging of CD133 + tumor stem cells . Proceedings of the National Academy of Sciences 111:6.
Crossref
Liangbiao George Hu & David W. Clarke. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 26 .
John J. Connell, Grégoire Chatain, Bart Cornelissen, Katherine A. Vallis, Alastair Hamilton, Len Seymour, Daniel C. Anthony & Nicola R. Sibson. (2013) Selective Permeabilization of the Blood–Brain Barrier at Sites of Metastasis. JNCI: Journal of the National Cancer Institute 105:21, pages 1634-1643.
Crossref
Aurélien Marabelle, Holbrook Kohrt, Idit Sagiv-Barfi, Bahareh Ajami, Robert C. Axtell, Gang Zhou, Ranjani Rajapaksa, Michael R. Green, James Torchia, Joshua Brody, Richard Luong, Michael D. Rosenblum, Lawrence Steinman, Hyam I. Levitsky, Victor Tse & Ronald Levy. (2013) Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. Journal of Clinical Investigation 123:6, pages 2447-2463.
Crossref
Ankit I. Mehta, Adam M. Brufsky & John H. Sampson. (2013) Therapeutic approaches for HER2-positive brain metastases: Circumventing the blood–brain barrier. Cancer Treatment Reviews 39:3, pages 261-269.
Crossref
Kristian Sexton, Kenneth Tichauer, Kimberley S. Samkoe, Jason Gunn, P. Jack Hoopes & Brian W. Pogue. (2013) Fluorescent Affibody Peptide Penetration in Glioma Margin Is Superior to Full Antibody. PLoS ONE 8:4, pages e60390.
Crossref
Lois A. Lampson. (2013) Brain tumor immunotherapy: seeing the brain in the body. Drug Discovery Today 18:7-8, pages 399-406.
Crossref
Said Younis, Itzhak Rosner, Doron Rimar, Nina Boulman, Michael Rozenbaum, Majed Odeh & Gleb Slobodin. (2013) Interleukin 6 Blockade–Associated Weight Gain With Abdominal Enlargement in a Patient With Rheumatoid Arthritis. JCR: Journal of Clinical Rheumatology 19:1, pages 48-49.
Crossref
Matthew E. Hardee, Ariel E. Marciscano, Christina M. Medina-Ramirez, David Zagzag, Ashwatha Narayana, Scott M. Lonning & Mary Helen Barcellos-Hoff. (2012) Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β. Cancer Research 72:16, pages 4119-4129.
Crossref
Gavin P. Dunn, Peter E. Fecci & William T. Curry. (2012) Cancer Immunoediting in Malignant Glioma. Neurosurgery 71:2, pages 201-223.
Crossref
Kunal S. Taskar, Vinay Rudraraju, Rajendar K. Mittapalli, Ramakrishna Samala, Helen R. Thorsheim, Julie Lockman, Brunilde Gril, Emily Hua, Diane Palmieri, Joseph W. Polli, Stephen Castellino, Stephen D. Rubin, Paul R. Lockman, Patricia S. Steeg & Quentin R. Smith. (2011) Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer. Pharmaceutical Research 29:3, pages 770-781.
Crossref
Hamdy A Azim & Hatem A Azim Jr. (2012) Systemic treatment of brain metastases in HER2-positive breast cancer: current status and future directions. Future Oncology 8:2, pages 135-144.
Crossref
Lois A. Lampson. 2013. Animal Models of Brain Tumors. Animal Models of Brain Tumors 3 20 .
Paul J. Carter. (2011) Introduction to current and future protein therapeutics: A protein engineering perspective. Experimental Cell Research 317:9, pages 1261-1269.
Crossref