Staphylococcus aureus meningitis complicated with intracranial hemorrhage and cerebral infarction: a case report

Abstract

Purpose

The case with staphylococcus aureus meningitis accompanied by intracranial hemorrhage and cerebral infarction is very rare and cerebrovascular complications are often associated with poor outcome.

Materials and methods

We describe the clinical characteristics and laboratory data of a patient with meningitis accompanied by cerebrovascular complications.

Results

The patient, a young male, was admitted to hospital with 3 weeks of fever, 10 days of slow reaction and 2 days of left limb strength decline. Neurological examination showed cognitive dysfunction, left central hemiplegia and meningeal irritation sign. Brain Imaging examination revealed intracranial hemorrhage and multiple cerebral infarction. The elevated leucocyte and protein, as well as low glucose of cerebrospinal fluid was observed. Cerebrospinal fluid and foot blister culture both suggested staphylococcus aureus infection. With the treatment of meropenem and glucocorticoid, the condition of our patient was improved.

Conclusions

Detection of pathogenic bacteria is the gold standard of diagnosis, and timely diagnosis and treatment for pathogens are the keys to a good prognosis for patients.

Keywords:

• Staphylococcus aureus
• meningitis
• secondary vasculitis
• intracranial hemorrhage
• cerebral infarction

Author contributions

Y. Jia and W. Wang were the major contributors in writing the manuscript. X. Wang and Y. Wang contributed to the diagnosis and treatment of the patient. L. Jiao contributed to the analysis of genetic examination. Y. Wang and L. Jiao contributed to checking the manuscript. All authors read and approved the final manuscript.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Ethics statement

All procedures were approved by the ethics committee of Xuanwu Hospital. Written informed consent was obtained from the patient for publication of this Case report and any accompanying images.

Data availability statement

The data that support the findings of this study are available from the corresponding author, LD Jiao, upon reasonable request.

Additional information

Funding

This work was supported by National Natural Science Foundation of China Grant [No. 81801283], National Natural Science Foundation of China Grant [No. 81771398], Beijing Key Clinical Speciality Excellence Project and National Support Provincial Major Disease Medical Services and Social Capability Enhancement Project.