Oxime ligands: Organometallic synthesis and catalysis

Abstract

Ligands are at the heart of coordination chemistry. They conjure the magic of transition metals expressed in organometallic catalysis. Phosphine or P-ligands have found vast utility in transition metal chemistry, though demanding tedious synthesis. Several N, S-based ligands also find application in organometallic chemistry. Oximes are easily derived from aldehydes and ketones by simple reactions with hydroxylamine. Thus, an extensive library of oximes is available with different structural and electronic variations essential for coordination chemistry and catalysis. Several compounds with complex structural features, unavailable for phosphorous ligands, can be readily converted into active oxime ligands in a single derivatization step. Oxime ligands and metal complexes are applied in synthesizing diverse organic molecules and thus versatile ligands in organotransition metal chemistry.

Graphical Abstract

Keywords:

• cobaloxime
• cross-coupling
• oximes
• oxime palladacycles
• radical cyclization

Acknowledgements

The author is thankful to OCD, NCL, CSIR for providing research facilities

Conflicts of interest

The author declares no conflicts of interest.