Evaluating the impact of the COVID-19 pandemic on tertiary gynaecological cancer care delivery: a population based study

Abstract

During the COVID-19 pandemic, reports of delays and alterations in cancer treatment pathways have emerged. We aim to evaluate the proportional impact of the pandemic over time on standard care delivery in a large tertiary gynaecological cancer centre. Consecutive patient records from weekly multidisciplinary team meetings were collected prospectively between 6 March 2020 and 26 March 2021. In total, 1943 patient discussions were held in our multidisciplinary team meetings during the study period, with 2.1% standard management decisions being altered due to the pandemic, the majority of which occurred during the first wave. Amongst alterations, 87.5% were deferral of surgery, and, in 62.5% of cases, were due to reduced critical care capacity. The majority of patients were offered alternative treatment, and surgery once resources permitted. During subsequent waves of COVID-19, with similar reductions in critical care capacity, we demonstrate avoidance of a second major increase in standard care pathway alterations.

IMPACT STATEMENT

• What is already known about the subject? Recent evidence has demonstrated significant delays to cancer surgery during the COVID-19 pandemic. However, few studies have objectively evaluated the quantity and nature of deviations from both surgical and non-surgical standard gynaecological cancer care pathways.

• What the results of this study add? We examined in detail the effects of the pandemic on tertiary gynaecological cancer service delivery in our centre. The main impact was in the ability to perform major surgery due to reduced critical care capacity. However, with the majority of standard care alterations clustered during the first wave of the pandemic, we demonstrate how the implementation of a COVID-19 mitigation plan minimised service disruption during subsequent waves.

• What the implications are of these findings for clinical practice and/or further research? This study reinforces the importance of protecting gynaecological cancer services during situations where resources are limited. Having identified several key factors affected by the pandemic, we hope that our results will support others in coordinating responses to similar scenarios in future. Having not examined the effects of the pandemic on primary and secondary level cancer services, further research will be needed to evaluate the overall impact on long term patient outcomes.

Keywords:

• COVID-19
• pandemic
• gynecological cancer
• cancer surgery

Acknowledgements

We thank the Pan-Birmingham Gynaecological Cancer Centre, and Sandwell and West Birmingham Hospitals NHS Trust, for provision of the data.

Ethics approval

Ethics approval was not required as this is an anonymised study. Approval was gained from Sandwell and West Birmingham Hospitals NHS Trust governance department to collect anonymous patient data and undertake the study.

Author contributions

JL-Z and JY conceived the idea for the study, and, along with RP, participated in its design and coordination, and provided final approval of the version to be published. JL-Z, MW, EG and HB performed data collection. JL-Z and RP performed data analysis. JL-Z wrote the manuscript with revisions and corrections provided by JY. All authors read and approved the final manuscript.

Disclosure statement

No potential conflict of interest was reported by the author(s).