Toward an improved assessment of quality of life in endometriosis: evaluation of the Spanish version of the Endometriosis Health Profile 30

Abstract

Purpose

Our main objective is to evaluate the psychometric properties of the Spanish version of the EHP-30 questionnaire. The secondary aim is to evaluate the differences in the scores of the core EHP-30 scales between patients with either surgical treatment or conservative management of endometriosis.

Methods

Cross-sectional study conducted into a tertiary hospital endometriosis reference unit. All patients (n = 223) pre-surgically completed the core EHP-30 questionnaire, the EQ-5D questionnaire (n = 184) and a visual analogue scale (n = 210) for endometriosis-related pain. Demographical and clinical data were recorded.

Results

Psychometric characteristics of the Spanish core EHP-30 questionnaire were investigated. Statistical analyses confirmed the five-structure factor, a high degree of internal consistency and of item-total correlation for all the assessed items. Convergent validity between EQ-5D and EHP-30 items and between VAS and EHP-30 subscale pain was observed. Additionally, patients with surgical management rendered significantly higher scores in the core EHP-30 subscales “pain” and “control and powerlessness”.

Conclusions

We present the reliability, validity and acceptability of the Spanish core EHP-30 questionnaire, providing clinicians and researchers with an improved tool to assess the endometriosis-related quality of life. Additionally, we show that patients subsidiaries of surgical treatment for endometriosis present with higher pain and powerlessness than those with conservative management.

Keywords:

• Endometriosis Health Profile-30
• quality of life assessment
• visual analogue scale
• EQ-5D
• endometriosis

Acknowledgements

The authors thank all the women who accepted to participate in this study.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The work was supported by grants from the Spanish Ministry of Health (Instituto de Salud Carlos III, ISCIII) together with fundings from the European Union (Fondos Europeos para el Desarrollo Regional, FEDER), reference PI14/01309 and PI17/01945. Additionally, the work was supported by an intramural grant from our Institution (Fundación para la Investigación del Hospital General Universitario de Valencia), reference FIHGUV-2019. Josep Marí Alexandre (J.M.-A.) is supported by a post-doctoral grant from the regional government (Generalitat Valenciana), reference APOST/2019/087.