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Visual Function and Imaging

Usefulness of Polarization-sensitive Optical Coherence Tomography-derived Attenuation-coefficient Images to Visualize the Internal Structure of the Filtering Bleb

, , MD, PhD, , MD, PhD, , PhD &
Pages 606-609 | Received 16 May 2020, Accepted 06 Sep 2020, Published online: 04 Oct 2020
 

ABSTRACT

Purpose/Aim of the study

Polarization-sensitive anterior-segmental optical coherence tomography (PS-OCT) is useful to evaluate the filtering blebs after trabeculectomy. However, the attenuation phenomenon of OCT signal disturbs the visibility of intra-bleb’s structure and distribution of birefringence; a specific parameter of PS-OCT. This study aimed to evaluate the effectiveness of the attenuation-coefficient image of the filtering blebs.

Materials and methods

This study included 25 eyes 6 months after TLE. The attenuation-coefficient image of blebs was calculated from OCT intensity signal information. The contrast level of the image (reflectivity of bleb’s surface wall/reflectivity of scleral flap) in both attenuation-coefficient image and intensity image and the height of the bleb’s wall were calculated. The improvement extent of contrast was defined as the ratio of contrast (attenuation-coefficient image’s contrast/intensity image’s contrast). We compared the contrast of attenuation-coefficient image and intensity image and investigated the relationship between improvement extent of contrast and height of bleb’s wall.

Results

The contrast of the attenuation-coefficient image (317.7 ± 255.4%) was significantly higher than that of the intensity image (39.1 ± 24.5%) (P < .01) and the improvement extent of contrast was 9.5 ± 4.6 times. Furthermore, there was a positive correlation between the improvement extent of contrast and the height of the bleb’s wall (r = 0.44, P = .03).

Conclusions

The contrast of the image at depth of filtering blebs was improved by attenuation-coefficient image. It is suggested that the attenuation-coefficient image may improve the visibility of the structure and distribution of birefringence in the blebs compared to the intensity image.

Additional information

Funding

This work was supported by the Japan Society for the Promotion of Science (JSPS) [KAKENHI Grant-in-Aid for Scientific Research (B)]; Research grant Alcon Japan Ltd.

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