Orbital Sarcoidosis in a High TB Endemic Country – A Case Series from South India

ABSTRACT

Aim: We report a series of orbital sarcoid in a south Indian patient population and their outcome.

Materials & Methods: Retrospective interventional case series.

Results: Eleven out of 144cases of biopsy-proven sarcoidosis had orbital involvement. The mean age was 50.64 ± 9.52years and was more commonly seen in women (90.91%). Unilateral presentation with right orbit involvement was more common. Bilateral lacrimal gland enlargement (4cases), inferior orbital mass presenting as proptosis (4cases), preseptal mass above upper eyelid (2cases) and orbital mass encasing the globe (1case) were the different types of orbital presentation. All cases had a dry eye and a negative mantoux test. CT thorax was abnormal in 7cases (63.61%). Biopsy in all cases showed noncaseating granulomatous inflammation. Oral steroids were the standard mode of treatment and none of the cases had recurrences.

Conclusions: Orbital sarcoidosis is seen in a high TB endemic country like India and is definitely underreported.

KEYWORDS:

• Sarcoid
• orbital
• uveitis
• steroids
• proptosis
• Dacryoadenitis

Declaration of Interest Statement

The authors have no financial interest in the study