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Ocular Immunology and Inflammation Volume 31, 2023 - Issue 6: COVID-19 and the Eye
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Letters to the Editor

Neuropathic Corneal Pain as Debilitating Manifestation of LONG-COVID

Johannes Nikolaus Woltschea Department of Ophthalmology, Medical University of Graz, Graz, AustriaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2240-6736View further author information
, Med. StudentORCID Icon,
Jutta Horwath-Wintera Department of Ophthalmology, Medical University of Graz, Graz, AustriaView further author information
, Priv.-Doz. Dr.med.univ.,
Christian Dornb Department of Anaesthesiology and Intensive Care, Medical University of Graz, Graz, AustriaView further author information
, Ass.-Doz. Dr.med.univ.,
Ingrid Boldina Department of Ophthalmology, Medical University of Graz, Graz, AustriaView further author information
, Priv.-Doz. Dr.med.univ.,
Gernot Steinwendera Department of Ophthalmology, Medical University of Graz, Graz, AustriaView further author information
, Priv.-Doz. Dr.med.univ. Dr.scient.med.,
Astrid Heidingera Department of Ophthalmology, Medical University of Graz, Graz, AustriaView further author information
, Dr.med.univ. &
Nora Woltschea Department of Ophthalmology, Medical University of Graz, Graz, AustriaORCID Iconhttps://orcid.org/0000-0001-6856-4046View further author information
, Dr.med.univ.ORCID Icon show all
Pages 1216-1218 | Received 10 Mar 2022, Accepted 13 Jun 2022, Published online: 07 Jul 2022
 
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ABSTRACT

This report illustrates the case of a female patient suffering from severe ocular discomfort, tinnitus and ageusia, 7 months after a SARS-CoV-2 infection. The medical history implicated a diagnosis of LONG-COVID with ocular pain as the most debilitating symptom. In-vivo confocal microscopy revealed corneal microneuromas with hyperreflectivity and irregular enlargement of nerve endings in both eyes, which led to the diagnosis of neuropathic corneal pain. The aim of this report is to increase awareness that COVID-19 induced neuropathic pain can also occur in the cornea representing the human body’s most richly innervated tissue.

Disclosure statement

We know of no conflicts of interest associated with this publication, and there has been no financial support for this work that could have influenced its outcome.

Additional information

Funding

The authors received no direct funding for this research.

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