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Acknowledgments
The authors thank Noemi Castelletti, Cristoforo Simonetto and Markus Eidemüller for fruitful discussions. Noemi has also contributed .
Disclosure statement
No potential conflict of interest was reported by the author(s).
Notes
1 In radiation research they are often termed Biologically Based Dose Response (BBDR) models (Preston Citation2015, Citation2017). Since not only radiation-induced but in principle all carcinogenic processes are addressed by this model type the abbreviation BBCR is suggested.
Additional information
Notes on contributors
Jan Christian Kaiser
Dr. Jan Christian Kaiser leads the working group ‘Integrative Modeling’ in the Institute of Radiation Medicine at the Helmholtz Zentrum München, German Research Center for Environmental Health, in Munich, Germany. He holds a doctoral and masters’ degree in statistical physics. His research involves integration of molecular biology and radiation epidemiology in biologically based risk models.
Maria Blettner
Prof. Dr. Maria Blettner is the former Director of the Institute of Medical Biometry, Epidemiology and Informatics at the University Medical Center in Mainz, Germany. The focus of her research is in radiation- and cancer epidemiology and methods for clinical and epidemiological studies. She is a member of the MELODI advisory board.
Georgios T. Stathopoulos
Dr. Georgios T. Stathopoulos leads the working group ‘Lung Carcinogenesis’ in the Comprehensive Pneumology Center at the Helmholtz Zentrum München, German Research Center for Environmental Health, in Munich, Germany. He holds basic and lung specialist medical degrees, as well as a doctoral degree in cancer biology. His research is focused on the biology of chest tumors.