Advanced search
Publication Cover
Leukemia & Lymphoma Volume 61, 2020 - Issue 4
Submit an article Journal homepage
165
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Prognostic value of interim 18F-FDG PET/CT in T-cell lymphomas

Long QianDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China;
,
Miaoming YanDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China;
,
Wei ZhangDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-0063-6490
ORCID Icon,
Daobin ZhouDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China;
,
Yan ZhangDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China; ORCID Iconhttp://orcid.org/0000-0003-0244-218X
ORCID Icon,
Li HuoDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China
,
Yaping LuoDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China
,
Yingqiang ZhangDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China
&
Shaoxuan HuDepartment of Hematology, Peking Union Medical College Hospital, Beijing, China;
show all
Pages 927-933 | Received 16 Oct 2019, Accepted 16 Nov 2019, Published online: 04 Dec 2019
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

18F-FDG PET/CT is recommended for staging and response assessment in FDG-avid lymphomas, such as HL and DLBCL. But evidence of PET/CT regarding T-cell lymphomas (TCLs) was limited. In this retrospective study, we conducted survival analysis using interim PET/CT in 51 TCLs patients. PET/CT were reported using the Deauville 5-point score (DS) and the ΔSUVmax. In univariate analysis, I-PET/CT had a significant prognostic value of survival outcomes based on DS (p < .001 for progression-free survival (PFS), p = .010 for overall survival (OS)) and ΔSUVmax (p < .001 for PFS, p = .023 for OS). In multivariate analysis, DS remained a statistically independent predictor of PFS (p < .001) and OS (p = .017). ΔSUVmax remained a statistically independent predictor of PFS (p = .008), but not of OS (p = 0.311). Therefore, DS on I-PET/CT had a remarkable value of predicting survival outcomes in TCLs.

Disclosure statement

No potential conflict of interest was reported by the authors.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,065.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.