Authorship contributions
CKC and LJN: Designed the study.
CKC, PJ and MN: Collected and assembled the data.
CKC, YQ and LF: Analyzed and interpreted the data.
CKC, MR, FS, NF, YQ, LF, JW, SSN, FBH, CF, LJN: Wrote the manuscript.
All authors gave final approval for the manuscript.
MR, FS, NF, LF, JW, SSN, FBH, CF, LJN: Provided study materials and patients.
Disclosure statement
CKC, MR, YQ, LF, FS, PJ, MN, LF, FBH: No conflicts of interest.
NF: received research support from Celgene, Roche, Janssen, TG Therapeutics and AbbVie; served as consultant and advisory board member for Celgene, Roche, Janssen, TG therapeutics and AbbVie.
JW: has received research support from Novartis, Celgene, Janssen, Kite/Gilead, Unum, Genentech, Curis and 47 Inc; served as consultant and advisory board member for Novartis, Celgene, Juno, Janssen, Kite/Gilead, MorphoSys, Genentech and Curis.
SSN: has received research support from Kite/Gilead, Cellectis, Poseida, Merck, Acerta, Karus, BMS, Unum Therapeutics, Allogene, and Precision Biosciences; served as consultant and advisory board member for Kite/Gilead, Celgene, Novartis, Unum Therapeutics, Pfizer, Merck, Precision Biosciences, Cell Medica, Incyte, Allogene, Calibr, and Legend Biotech; has patents related to cell therapy.
CF: has received research support from AbbVie, Acerta Pharma, Celgene, Gilead Sciences, Infinity Pharmaceuticals, Janssen Pharmaceuticals, Millenium/Takeda, National Institutes of Health, Onyx Pharmaceuticals, Pharmacyclics and Spectrum Pharmaceuticals; served as consultant and advisory board member for Spectrum Pharmaceuticals, Celgene, Optum Rx, Seattle Genetics, Kite/Gilead and Bayer.
LN: has received research support from TG Therapeutics, Janssen, Genentech and Celgene; has served as consultant and advisory board member for TG Therapeutics, Novartis, Janssen, Spectrum Pharmaceuticals, Kite/Gilead, Genentech, Bayer and Celgene.