Acknowledgements
Trial registration: clinicaltrials.gov identifier NCT02232386.
Author contributions
NP, RF, and AG designed the research study; MSDP, SI, and MLM carried out the lab work; MSDP, FRM, AC, GMR, and IDG analyzed the data; NP, RF, and AG wrote the paper.
Disclosure statement
No potential conflict of interest was reported by the author(s).