Effect of laparoscopic surgery for colorectal cancer with N. O. S. E. on recovery and prognosis of patients

Abstract

Objective

To investigate the effect of laparoscopic surgery in colorectal cancer (CRC) patients with natural orifice specimen extraction (NOSE) on the recovery and quality of life (QOL) of patients.

Material and methods

Ninety-two eligible patients were randomly assigned into two groups: the traditional laparoscopy group (L group, n = 46) and the laparoscopic transanal specimen extraction group (NL group, n = 46). General data, surgery-related indicators, postoperative recovery, and prognosis were compared and analyzed between the two groups.

Results

A total of 46 patients in each group were enrolled in this study. The general data and surgery-related indicators were comparable between the two groups (all p > .05). There were no significant differences in the time of first flatus, bleeding, obstruction, constipation, and infectious complications between the two groups (all p > .05). The differences in the incidence of postoperative diarrhea, pain degree, and satisfaction on the aesthetics of the abdominal wall showed significant differences (χ² = 6.133, p = .013; χ² = 12.116, p = .017; χ² = 13.463, p = .004). The postoperative follow-up time was 3–53 months. There were no significant differences in the postoperative hospital stay, medical costs, hospital readmission rate, incidence of incisional hernia, overall survival, disease-free survival, and QOL between the two groups (all p > .05). Conclusion: Laparoscopic surgery with NOSE for eligible patients with CRC was a feasible choice.

Keywords:

• Laparoscopic surgery
• colorectal cancer
• natural orifice specimen extraction

Declaration of interest

No potential conflict of interest was reported by the author(s).

Data availability statement

Some or all data, models, or code generated or used during the study are available from the corresponding author by request.

Additional information

Funding

This study was funded by project of Sichuan health and Family Planning Commission, No. 150010, China.