Investigation of the effectiveness of aerobic exercise training in individuals with ankylosing spondylitis: Randomized controlled study

Abstract

Objective

To investigate the effect of the addition of aerobic training to spinal mobility exercises on disease-specific outcomes and functional exercise capacity, aerobic capacity and respiratory muscle strength of ankylosing spondylitis (AS) patients.

Methods

The study included 31 volunteers (mean age: 44.90 ± 11.52 years) diagnosed with AS. The demographic characteristics and disease-related data of all subjects were recorded, then, the Bath AS Disease Activity Index (BASDAI), Bath AS Metrology Index (BASMI) and Bath AS Disease Function Index (BASFI), the 6-minute walk test, the Bruce Treadmill Test and spirometry were used, respectively. The intervention group attended a 12-week program of aerobic exercise sessions, plus supervised spinal mobility exercises, 3 days a week. The control group performed the supervised spinal mobility exercises only, 3 times a week, for 12 weeks.

Results

There was a significant improvement in BASDAI (p = .002), BASMI (p = .021), 6 DYT (p = .036), VO₂ max (p = .000), MIP (p = .005) and MEP (p = .022) results in the intervention group after 12 weeks of training. In the comparisons of the pre-treatment and post-treatment differences, BASDAI (p = .032) decreased and VO₂ (p = .001) max increased, showing significant improvements in the intervention group and these values were maintained.

Conclusion

It is striking that improvements in all parameters except BASFI were achieved in the aerobic training group. These results demonstrate that an aerobic exercise program should be included in an individual exercise prescription for the management of AS.

Keywords:

• Aerobic exercise
• ankylosing spondilitis
• functional exercise capacity
• respiratory muscle strength
• spinal mobility exercise

Acknowledgments

Approval for the study was granted by the Non-Interventional Clinical Research Ethics Committee of Pamukkale University (decision no:: 60116787-020/49880 dated 01.08.2017). Informed consent was obtained from all the study participants. Also, we conducted our studies in compliance with recognized the principles of the Declaration of Helsinki.

Conflict of interest

None.

Additional information

Funding

Project 2019KKP038 (2019KRM004) was supported by Pamukkale University for the presentation of the poster paper at the European Congress of Rheumatology 2019.