Advanced search
Publication Cover
The Journal of Maternal-Fetal & Neonatal Medicine Volume 35, 2022 - Issue 25
Submit an article Journal homepage
118
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Second-trimester abdominal circumference discordance and adverse perinatal outcomes in monochorionic twins

A. Zhanga Qingdao Women and Children’s Hospital, Qingdao University School of Medicine, Qingdao, PR China
,
T. T. Stolkb Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands
,
E. Lopriorec Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
,
L. Sund Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, PR China
,
T. Duand Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, PR China
&
D. Oepkesb Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden, The NetherlandsCorrespondence[email protected]
Pages 7316-7321 | Received 13 Jan 2021, Accepted 21 Jun 2021, Published online: 05 Jul 2021
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Objective

The perinatal outcomes in second-trimester abdominal circumference (AC) discordant twins are yet to be established. The aim of this study was to ascertain perinatal risks associated with second-trimester AC discordance in monochorionic (MC) twins.

Method

We conducted a retrospective study of all MC twin pregnancies over a 7-year period. Intertwin AC discordance at 14–26 gestational weeks was analyzed in relation to Doppler abnormalities, obstetric complications, and perinatal adverse outcomes.

Results

A total of 246 MC twin pregnancies were included in the analysis. The smaller twins of second-trimester AC discordant pairs were at increased prevalence of abnormal umbilical artery flow (50% versus 24%, p < .001) and low positive A wave of ductus venous flow (24% versus 9%, p = .002). The second-trimester AC discordant twins were at increased risk of oligohydramnios in smaller twin (OR = 2.44, 95% CI = 1.37–4.32, p < .01), cardiomegaly in larger twin (OR = 2.95, 95% CI = 1.01–8.60, p < .05), birth weight of either twin below the 10th percentile for gestational age (OR = 5.56, 95% CI = 2.67–11.59, p < .001), birth weight discordance > 25% (OR = 9.41, 95% CI = 4.46–19.87, p < .001), IUFD (OR = 3.26, 95% CI = 1.76–6.05, p < .001), and severe neonatal morbidity (OR = 1.83, 95% CI = 1.03–3.26, p < .05). The intact survival rate in discordant and concordant twin pairs was 70% and 89%, respectively (p < .001).

Conclusions

Early and increase fetal surveillance of the second-trimester AC discordant twins should be utilized to establish perinatal risks, thus allowing prenatal care to improve.

Disclosure statement

The authors report that there are no conflicts of interest.

This work was supported by Qingdao Social Science Planning Project (QDSKL2001378) and Qingdao Postdoctoral Project (201922).

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later
PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.