Effects of probiotic bacteria of Lactobacillus acidophilus and Lactobacillus casei on aflatoxin B₁ detoxification within a simulated gastrointestinal tract model

Abstract

The present study was objected to assess the ability of lactic acid bacteria in the reduction of aflatoxin B₁ (AFB₁) in a simulated human gastrointestinal tract. In this work, eight treatments were prepared to compare the ability of noted probiotic bacteria in AFB₁ reduction in different simulated gastrointestinal conditions. The results of the present study revealed a significant reduction in AFB₁ in all of the treatments in which the highest reduction rate was observed by L. acidophilus in the absence of sterilized milk. Moreover, the findings showed that bacteria, gastric juice, and small intestine may contribute to the reduction of AFB₁.

Keywords:

• Probiotic bacteria
• aflatoxin B1
• toxin binding
• digestive system
• detoxification

Acknowledgments

This study was a Ph.D. thesis project which was supported by the Faculty of Veterinary Medicine of Urmia University.

Disclosure statement

No potential conflict of interest was reported by the author(s).