Recalling the severity of nausea and vomiting of pregnancy – a study using Pregnancy-Unique Quantification of Emesis Questionnaire

Figures & data

Table 1. Basic characteristics of the women according to different gestational weeks.

	≤20 gwks (n = 1209)	>20 gwks (n = 1134)		≤20 gwks (n = 1209)	≥24 gwks (n = 495)		≤16 gwks (n = 554)	≥ 24 gwks (n = 495)
	Mean (SD, range)/median [IQR]	Mean (SD, range)/median [IQR]	p Value	Mean (SD, range)/median [IQR]	Mean (SD, range)/median [IQR]	p Value	Mean (SD, range)/median [IQR]	Mean (SD, range)/Median [IQR]	p Value
Gwk	17 [15, 18]	23 [22, 25]		17 [15, 18]	26 [25, 28]		15 [14, 16]	26 [25, 28]
Age (years)	30.0 (4.7, 18–44)	30.6 (4.7, 15–46)	.002	30.0 (4.7, 18–44)	30.8 (4.7, 15–44)	.0008	29.5 (4.7, 18–44)	30.8 (4.7, 15–44)	<.0001
Pre-pregnancy BMI (kg/m^2)	23.3 [21.2, 26.4]	23.7 [21.5, 26.5]	.074	23.3 [21.2, 26.4]	23.7 [21.7, 26.4]	.036	23.2 [20.9, 26.4]	23.7 [21.7, 26.4]	.020
Previous pregnancies	1 [0, 2]	1 [0, 2]	.901	1 [0, 2]	1 [0, 2]	.982	1 [0, 2]	1 [0, 2]	.180
Previous deliveries	1 [0, 1]	1 [0, 1]	.603	1 [0, 1]	1 [0, 1]	.617	0 [0, 1]	1 [0, 1]	.041
	n (%)	n (%)		n (%)	n (%)		n (%)	n (%)
Smoking			.859			.104			.068
No	1019 (94.4)	972 (94.3)		1019 (94.4)	432 (96.4)		457 (93.8)	432 (96.4)
Yes	60 (5.6)	59 (5.7)		60 (5.6)	16 (3.6)		30 (6.2)	16 (3.6)
Marital status			.647			.753
Cohabited	1121 (96.4)	1062 (96.0)		1121 (96.4)	464 (96.1)		514 (96.6)	464 (96.1)	.640
Single	42 (3.6)	44 (4.0)		42 (3.6)	19 (3.9)		18 (3.4)	19 (3.9)
Employment			.297			.628
Working	852 (82.4)	822 (84.1)		852 (82.4)	358 (83.5)		371 (79.8)	358 (83.5)	.158
Not working	182 (17.6)	155 (15.9)		182 (17.6)	71 (16.5)		94 (20.2)	71 (16.5)

Notes: Total n = 2343. BMI: body mass index; IQR: interquartile range; gwks: gestational weeks; SD: standard deviation.

Figure 1. PUQE score categories according to the gestational week at reply. Gwks: gestational weeks; NVP: nausea and vomiting of pregnancy; PUQE: Pregnancy-Unique Quantification of Emesis questionnaire.

Table 2. Comparisons of PUQE scores and PUQE questions according to different gestational weeks.

	≤20 gwks (n = 1209)	>20 gwks (n = 1134)		≤20 gwks (n = 1209)	≥24 gwks (n = 495)		≤16 gwks (n = 554)	≥ 24 gwks (n = 495)
	Mean (SD) Median [IQR]	Mean (SD) Median [IQR]	p Value	Mean (SD) Median [IQR]	Mean (SD) Median [IQR]	p Value	Mean (SD) Median [IQR]	Mean (SD) Median [IQR]	p Value
PUQE total score	7.4 (3.1) 7 [5, 10]	7.4 (3.1) 7 [5, 10]	.683	7.4 (3.1) 7 [5, 10]	7.3 (3.1) 7 [5, 10]	.386	7.6 (3.0) 7 [5, 10]	7.3 (3.1) 7 [5, 10]	.109
PUQE Question 1	3.3 (1.4) 3 [2, 5]	3.2 (1.4) 3 [2, 5]	.081	3.3 (1.4) 3 [2, 5]	3.1 (1.4) 3 [2, 5]	.014	3.4 (1.4) 3 [2, 5]	3.1 (1.4) 3 [2, 5]	.005
PUQE Question 2	1.7 (1.1) 1 [1, 2]	1.8 (1.1) 1 [1, 2]	.084	1.7 (1.1) 1 [1, 2]	1.8 (1.1) 1 [1, 2]	.138	1.8 (1.0) 1 [1, 2]	1.8 (1.1) 1 [1, 2]	.484
PUQE Question 3	2.4 (1.4) 2 [1, 3]	2.4 (1.4) 2 [1, 3]	.682	2.4 (1.4) 2 [1, 3]	2.3 (1.4) 2 [1, 3]	.576	2.4 (1.4) 2 [1, 3]	2.3 (1.4) 2 [1, 3]	.253

Notes: Total n = 2343. PUQE total score (range 3–15) is the sum of the points of the three PUQE questions (range 1–5 points per question).

Gwks: gestational week; IQR: interquartile range; PUQE: Pregnancy-Unique Quantification of Emesis Questionnaire.

Data availability statement

The dataset of this study is available from the corresponding author upon reasonable request.