Abdominal subcutaneous fat thickness combined with a 50-g glucose challenge test at 24-28 weeks of pregnancy in predicting gestational diabetes mellitus

Figures & data

Figure 1. Flowchart of the study.

Table 1. Characteristics of pregnant woman with and without gestational diabetes in the gestational diabetes screening program between 24 and 28 weeks of gestation.

	Gestational diabetes group (n = 58)		Pregnant woman without gestational diabetes (n = 670)
	Mean ± std	Median (Q1-Q3)	Mean ± std	Median (Q1-Q3)	p-value
Maternal age, years	29.4 ± 5.6	32 (26-39)	25.9 ± 4.8	29 (22-36)	<0.001
Gravidity, n	4.7 ± 1.6	4 (2-6)	2.5 ± 1.4	3 (1-5)	<0.001
Parity, n	3.4 ± 1.8	3 (1-5)	2.2 ± 1.3	2 (0-4)	<0.001
History of abortion, n (%)	4 (6.9%)		37 (5.5%)		0.293
Previous caesarean section, n (%)	13 (22.4)		162 (24.1)		0.571
Gestational week at screening	26.1 ± 1.8	26 (24-28)	26.3 ± 1.4	26 (24-28)	0.197
Gestational weight gain, kg	6.2 ± 3.7	6 (5-10)	5.9 ± 2.8	5 (4-10)	0.086
Body mass index, kg/m^2	27.7 ± 4.9	28.2 (26.6-31.3)	25.2 ± 3.1	25.4 (24.1-30.3)	<0.001
Abdominal subcutaneous fat tissue thickness, mm	20.1 ± 1.6	20.9 (16.8-25.9)	16.8 ± 1.1	16.6 (15.2-21.1)	<0.001

Bold values denote statistical significance at the p-value < 0.05 level.

Table 2. Prediction of gestational diabetes mellitus cases wit a positive 50-g glucose challenge test in combination with abdominal subcutaneous fat thickness value >18.1 mm.

	Sensitivity	Specificity	Positive predictive value	Negative Predictive value
Positive 50-g GCT and/or ASFT >18.1 mm	87.9%	88.7%	36.0%	99.7%

GCT: glucose challenge test; ASFT: abdominal subcutaneous fat thickness.

Data availability statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.