Temperature data analysis for 22 patients with advanced cervical carcinoma treated in Rotterdam using radiotherapy, hyperthermia and chemotherapy: A reference point is needed

Figures & data

Figure 1. Vagina all lumen T₂₀ and T₉₀ vs. vagina all lumen T₅₀.

Table I.  Average temperature (°C) in bladder, vagina and rectum obtained during deep hyperthermia treatment in 22 patients with locally advanced cervical carcinoma. Numbers in parentheses show 1 SD.

	Bladder		Vagina		Rectum
Index	Tumour indicative	All lumen	Tumour contact	All lumen	Tumour indicative	All lumen
Tmean	40.8 (0.7)	40.6 (0.7)	39.8 (0.8)	40.0 (0.7)	40.5 (0.6)	40.5 (0.6)
Tmax	41.6 (0.8)	41.8 (0.7)	40.7 (1.0)	41.3 (0.8)	41.7 (0.8)	41.9 (0.7)
T20	41.2 (0.7)	41.1 (0.7)	40.2 (0.8)	40.6 (0.7)	40.9 (0.7)	40.9 (0.6)
T50	40.8 (0.7)	40.6 (0.7)	39.7 (0.8)	40.0 (0.8)	40.5 (0.7)	40.5 (0.6)
T90	40.2 (0.8)	39.8 (0.8)	39.2 (0.7)	39.2 (0.8)	39.9 (0.7)	39.7 (0.7)

T_mean, T₂₀, T₅₀ and T₉₀ are calculated between 30 min after treatment start time and end of the treatment. T_max is calculated between start of treatment and end of the treatment.

Table II.  Average T₂₀, T₅₀ and T₉₀ in different location of temperature measurements during deep hyperthermia treatment of patients with locally advanced cervical carcinoma treated with radiotherapy, hyperthermia and chemotherapy. Numbers in parentheses show 1 SD.

Lumen	Thermometry method	Location of the temperature measurement	T20 (°C)	T50 (°C)	T90 (°C)
Vagina	Intra-vaginal	The deepest 5 cm of vaginal lumen	40.1 (0.9)	39.8 (0.9)	39.2 (0.8)
Vagina	Intra-vaginal	All vagina lumen	40.6 (0.7)	40.0 (0.8)	39.2 (0.8)
Bladder, vagina, and rectum	Intra-luminal	Bladder, vagina, and rectum lumens	40.9 (0.7)	40.4 (0.6)	39.6 (0.8)

Figure 2. A typical temperature profile along the thermal mapping catheter inserted in the vagina. Position 0 cm represents the deepest point in tissue whereas the transition between inside and outside the lumen is at 11–12 cm.

Figure 3. Vagina all lumen T₅₀ in the first and last treatment plus range of maximum and minimum vagina T₅₀ (grey area) during all of the treatments.