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Original

Heat reactions in multiple sclerosis: An overlooked paradigm in the study of comparative fatigue

Pages 34-40 | Received 30 Apr 2008, Accepted 22 Jun 2008, Published online: 09 Jul 2009

Figures & data

Figure 1. Rectal temperature data redrawn from White et al. (2000) in MS patients either precooled (MS C) or not precooled (MS NC) vs. well trained subjects (Con) from the study of Easton et al. (2007) exercising at ∼60% maximum oxygen uptake. Panel A is the absolute change in rectal temperature from start to end of exercise. Panel B is the rate of increase in rectal temperature.

Figure 1. Rectal temperature data redrawn from White et al. (2000) in MS patients either precooled (MS C) or not precooled (MS NC) vs. well trained subjects (Con) from the study of Easton et al. (2007) exercising at ∼60% maximum oxygen uptake. Panel A is the absolute change in rectal temperature from start to end of exercise. Panel B is the rate of increase in rectal temperature.

Figure 2. The neuromuscular pathway leading to muscular contraction from the central nervous system (CNS). Neuromuscular fatigue can occur at any point along this pathway and be manifest as a reduction in force output. Note the structures and sites normally thought to be involved in central versus peripheral fatigue as indicated on the left of the figure.

Figure 2. The neuromuscular pathway leading to muscular contraction from the central nervous system (CNS). Neuromuscular fatigue can occur at any point along this pathway and be manifest as a reduction in force output. Note the structures and sites normally thought to be involved in central versus peripheral fatigue as indicated on the left of the figure.

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