Intraperitoneal perfusion chemotherapy and whole abdominal hyperthermia using external radiofrequency following radical D2 resection for treatment of advanced gastric cancer

Figures & data

Figure 1. Schematic diagram of intraperitoneal perfusion chemotherapy and whole abdominal hyperthermia.

Figure 2. The scheme of this study.

Table 1. Patient characteristics.

Items	N = 22
Age (years), median	51 (38–69)
Gender
Male	14
Female	8
Pathological type
Adenocarcinoma	14
Signet ring cell carcinoma	6
Mucinous adenocarcinoma	2
Stage
II	4
III A	9
III B	6
III C	3
Surgery mode
Subtotal gastrectomy	13
Total gastrectomy	9
Number of completed cycles of intraperitoneal perfusion chemotherapy with whole abdominal hyperthermia
3	3
4	4
5	4
6	11

Table 2. Toxicities related to treatment.

Adverse reactions	N = 22
	All grade	Grade 3/4
Leukocytopenia	15	4
Anemia	18	4
Thrombocytopenia	15	7
Trichomadesis	14	2
Liver dysfunction	12	2
Renal dysfunction	8	1
Cardiac dysfunction	4	0
Nausea/vomiting	18	3
Neurotoxicity	9	0
Chemical peritonitis	0	0

Table 3. Recurrence or metastases after treatment.

Recurrence or metastasis	N = 22
Total	14
Remnant gastric	5
Retroperitoneal lymph node metastasis	6
Hepatic metastasis	3
Peritoneal metastasis	1
Seroperitoneum	1